Basic Principles and Clinical Applications of CRISPR-Based Genome Editing

por Lim, Jung Min, Kim, Hyongbum Henry
Publicado 2022

Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption

por Gopalappa, Ramu, Suresh, Bharathi, Ramakrishna, Suresh, Kim, Hyongbum (Henry)
Publicado 2018

Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

por Cho, Sung-Rae, Suh, Hwal, Yu, Ji Hea, Kim, Hyongbum (Henry), Seo, Jung Hwa, Seo, Cheong Hoon
Publicado 2016

In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia

por Seo, Jung Hwa, Lee, Min-Young, Yu, Ji Hea, Kim, Myung-Sun, Song, Myungjae, Seo, Cheong Hoon, Kim, Hyongbum (Henry), Cho, Sung-Rae
Publicado 2016

DNA double-strand break-free CRISPR interference delays Huntington’s disease progression in mice

por Seo, Jung Hwa, Shin, Jeong Hong, Lee, Junwon, Kim, Daesik, Hwang, Hye-Yeon, Nam, Bae-Geun, Lee, Jinu, Kim, Hyongbum Henry, Cho, Sung-Rae
Publicado 2023

SpCas9 activity prediction by DeepSpCas9, a deep learning–based model with high generalization performance

por Kim, Hui Kwon, Kim, Younggwang, Lee, Sungtae, Min, Seonwoo, Bae, Jung Yoon, Choi, Jae Woo, Park, Jinman, Jung, Dongmin, Yoon, Sungroh, Kim, Hyongbum Henry
Publicado 2019

Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

por Song, Myungjae, Lim, Jung Min, Min, Seonwoo, Oh, Jeong-Seok, Kim, Dong Young, Woo, Jae-Sung, Nishimasu, Hiroshi, Cho, Sung-Rae, Yoon, Sungroh, Kim, Hyongbum Henry
Publicado 2021

In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model

por Noh, Byunghwa, Rim, John Hoon, Gopalappa, Ramu, Lin, Haiyue, Kim, Kyu Min, Kang, Min Jin, Gee, Heon Yung, Choi, Jae Young, Kim, Hyongbum Henry, Jung, Jinsei
Publicado 2022

Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

por Lee, Eun-Seo, Moon, Sanghoon, Abu-Bonsrah, Kwaku Dad, Kim, Yun Kyoung, Hwang, Mi Yeong, Kim, Young Jin, Kim, Seokjoong, Hwang, Nathaniel S., Kim, Hyongbum Henry, Kim, Bong-Jo
Publicado 2019

Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarcti...

por Cho, Hyun‐Min, Kim, Pyung‐Hwan, Chang, Hyun‐Kyung, Shen, Yi‐ming, Bonsra, Kwaku, Kang, Byung‐Jae, Yum, Soo‐Young, Kim, Joo‐Hyun, Lee, So‐Yeong, Choi, Min‐cheol, Kim, Hyongbum (Henry), Jang, Goo, Cho, Je‐Yoel
Publicado 2017

Sniper2L is a high-fidelity Cas9 variant with high activity

por Kim, Young-hoon, Kim, Nahye, Okafor, Ikenna, Choi, Sungchul, Min, Seonwoo, Lee, Joonsun, Bae, Seung-Min, Choi, Keunwoo, Choi, Janice, Harihar, Vinayak, Kim, Youngho, Kim, Jin-Soo, Kleinstiver, Benjamin P., Lee, Jungjoon K., Ha, Taekjip, Kim, Hyongbum Henry
Publicado 2023

An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

por Kim, Jinyoung, Park, Kihyoun, Kim, Min Jung, Lim, Hyejin, Kim, Kook Hwan, Kim, Sun-Woo, Lee, Eun-Seo, Kim, Hyongbum (Henry), Kim, Sung Joo, Hur, Kyu Yeon, Kim, Jae Hyeon, Ahn, Jin Hee, Yoon, Kun-Ho, Kim, Ji-Won, Lee, Myung-Shik
Publicado 2021

Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth

por Kim, Wonjoo, Lee, Sangeun, Kim, Han Sang, Song, Minjung, Cha, Yong Hoon, Kim, Young-Hoon, Shin, Jeonghong, Lee, Eun-Seo, Joo, Yeonsoo, Song, Jae J., Choi, Eun Ju, Choi, Jae W., Lee, Jinu, Kang, Moonkyung, Yook, Jong In, Lee, Min Goo, Kim, Yeon-Soo, Paik, Soonmyung, Kim, Hyongbum (Henry)
Publicado 2018