Technologies for Direct Detection of Covalent Protein–Drug Adducts

por Mons, Elma, Kim, Robbert Q., Mulder, Monique P. C.
Publicado 2023

Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput

por Jia, Yuqing, Kim, Robbert Q., Kooij, Raymond, Ovaa, Huib, Sapmaz, Aysegul, Geurink, Paul P.
Publicado 2022

Exploring the Versatility of the Covalent Thiol–Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease

por Mons, Elma, Kim, Robbert Q., van Doodewaerd, Bjorn R., van Veelen, Peter A., Mulder, Monique P. C., Ovaa, Huib
Publicado 2021

The Copper Active Site of CBM33 Polysaccharide Oxygenases

por Hemsworth, Glyn R., Taylor, Edward J., Kim, Robbert Q., Gregory, Rebecca C., Lewis, Sally J., Turkenburg, Johan P., Parkin, Alison, Davies, Gideon J., Walton, Paul H.
Publicado 2013

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection

por Kim, Robbert Q., Misra, Mohit, Gonzalez, Alexis, Tomašković, Ines, Shin, Donghyuk, Schindelin, Hermann, Filippov, Dmitri V., Ovaa, Huib, Đikić, Ivan, van der Heden van Noort, Gerbrand J.
Publicado 2020

Synthesis of Stable NAD(+) Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC

por Madern, Jerre M., Kim, Robbert Q., Misra, Mohit, Dikic, Ivan, Zhang, Yong, Ovaa, Huib, Codée, Jeroen D. C., Filippov, Dmitri V., van der Heden van Noort, Gerbrand J.
Publicado 2020

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity

por Kim, Robbert Q., Geurink, Paul P., Mulder, Monique P. C., Fish, Alexander, Ekkebus, Reggy, El Oualid, Farid, van Dijk, Willem J., van Dalen, Duco, Ovaa, Huib, van Ingen, Hugo, Sixma, Titia K.
Publicado 2019

Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins

por Voorneveld, Jim, Kloet, Max S., Wijngaarden, Sven, Kim, Robbert Q., Moutsiopoulou, Angeliki, Verdegaal, Marnix, Misra, Mohit, Đikić, Ivan, van der Marel, Gijsbert A., Overkleeft, Herman S., Filippov, Dmitri V., van der Heden van Noort, Gerbrand J.
Publicado 2022

Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells

por van der Wulp, Willemijn, Gram, Anna M., Bleijlevens, Boris, Hagedoorn, Renate S., Araman, Can, Kim, Robbert Q., Drijfhout, Jan Wouter, Parren, Paul W. H. I., Hibbert, Richard G., Hoeben, Rob C., van Kasteren, Sander I., Schuurman, Janine, Ressing, Maaike E., Heemskerk, Mirjam H. M.
Publicado 2023

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining

por Singh, Jenny Kaur, Smith, Rebecca, Rother, Magdalena B., de Groot, Anton J. L., Wiegant, Wouter W., Vreeken, Kees, D’Augustin, Ostiane, Kim, Robbert Q., Qian, Haibin, Krawczyk, Przemek M., González-Prieto, Román, Vertegaal, Alfred C. O., Lamers, Meindert, Huet, Sébastien, van Attikum, Haico
Publicado 2021

RNF26 binds perinuclear vimentin filaments to integrate ER and endolysosomal responses to proteotoxic stress

por Cremer, Tom, Voortman, Lenard M, Bos, Erik, Jongsma, Marlieke LM, ter Haar, Laurens R, Akkermans, Jimmy JLL, Talavera Ormeño, Cami MP, Wijdeven, Ruud HM, de Vries, Jelle, Kim, Robbert Q, Janssen, George MC, van Veelen, Peter A, Koning, Roman I, Neefjes, Jacques, Berlin, Ilana
Publicado 2023

Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2

por Gan, Jin, de Vries, Jelle, Akkermans, Jimmy J. L. L., Mohammed, Yassene, Tjokrodirijo, Rayman T. N., de Ru, Arnoud H., Kim, Robbert Q., Vargas, David A., Pol, Vito, Fasan, Rudi, van Veelen, Peter A., Neefjes, Jacques, van Dam, Hans, Ovaa, Huib, Sapmaz, Aysegul, Geurink, Paul P.
Publicado 2023

Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes

por van Tol, Bianca D. M., van Doodewaerd, Bjorn R., Lageveen-Kammeijer, Guinevere S. M., Jansen, Bas C., Talavera Ormeño, Cami M. P., Hekking, Paul J. M., Sapmaz, Aysegul, Kim, Robbert Q., Moutsiopoulou, Angeliki, Komander, David, Wuhrer, Manfred, van der Heden van Noort, Gerbrand J., Ovaa, Huib, Geurink, Paul P.
Publicado 2023

Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification

por Kolli, Surendra Kumar, Molina-Cruz, Alvaro, Araki, Tamasa, Geurten, Fiona J. A., Ramesar, Jai, Chevalley-Maurel, Severine, Kroeze, Hans J., Bezemer, Sascha, de Korne, Clarize, Withers, Roxanne, Raytselis, Nadia, El Hebieshy, Angela F., Kim, Robbert Q., Child, Matthew A., Kakuta, Soichiro, Hisaeda, Hajime, Kobayashi, Hirotaka, Annoura, Takeshi, Hensbergen, Paul J., Franke-Fayard, Blandine M., Barillas-Mury, Carolina, Scheeren, Ferenc A., Janse, Chris J.
Publicado 2022