Coexistence of open-angle glaucoma and sarcoidosis-associated optic neuropathy

por Jung, Eun Hye, Kim, Woonghee, Yoon, Ra Gyoung, Kim, Ko Eun
Publicado 2023

Drug repositioning targeting glutaminase reveals drug candidates for the treatment of Alzheimer’s disease patients

por Bayraktar, Abdulahad, Li, Xiangyu, Kim, Woonghee, Zhang, Cheng, Turkez, Hasan, Shoaie, Saeed, Mardinoglu, Adil
Publicado 2023

Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning

por Turanli, Beste, Zhang, Cheng, Kim, Woonghee, Benfeitas, Rui, Uhlen, Mathias, Arga, Kazim Yalcin, Mardinoglu, Adil
Publicado 2019

Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients

por Kim, Woonghee, Li, Mengzhen, Jin, Han, Yang, Hong, Türkez, Hasan, Uhlén, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2023

Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy

por Liao, Xinmeng, Ozcan, Mehmet, Shi, Mengnan, Kim, Woonghee, Jin, Han, Li, Xiangyu, Turkez, Hasan, Achour, Adnane, Uhlén, Mathias, Mardinoglu, Adil, Zhang, Cheng
Publicado 2023

A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma

por Yuan, Meng, Shong, Koeun, Li, Xiangyu, Ashraf, Sajda, Shi, Mengnan, Kim, Woonghee, Nielsen, Jens, Turkez, Hasan, Shoaie, Saeed, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2022

Classification of clear cell renal cell carcinoma based on PKM alternative splicing

por Li, Xiangyu, Turanli, Beste, Juszczak, Kajetan, Kim, Woonghee, Arif, Muhammad, Sato, Yusuke, Ogawa, Seishi, Turkez, Hasan, Nielsen, Jens, Boren, Jan, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2020

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning

por Li, Xiangyu, Kim, Woonghee, Juszczak, Kajetan, Arif, Muhammad, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Turkez, Hasan, Boren, Jan, Nielsen, Jens, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2021

Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase

por Battisti, Umberto Maria, Monjas, Leticia, Akladios, Fady, Matic, Josipa, Andresen, Eric, Nagel, Carolin H., Hagkvist, Malin, Håversen, Liliana, Kim, Woonghee, Uhlen, Mathias, Borén, Jan, Mardinoğlu, Adil, Grøtli, Morten
Publicado 2023

Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

por Battisti, Umberto Maria, Gao, Chunxia, Nilsson, Oscar, Akladios, Fady, Lulla, Aleksei, Bogucka, Agnieszka, Nain‐Perez, Amalyn, Håversen, Liliana, Kim, Woonghee, Boren, Jan, Hyvönen, Marko, Uhlen, Mathias, Mardinoglu, Adil, Grøtli, Morten
Publicado 2022

Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach

por Li, Xiangyu, Shong, Koeun, Kim, Woonghee, Yuan, Meng, Yang, Hong, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Turkez, Hasan, Shoaie, Saeed, Boren, Jan, Nielsen, Jens, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2022

Combined Metabolic Activators Accelerates Recovery in Mild‐to‐Moderate COVID‐19

por Altay, Ozlem, Arif, Muhammad, Li, Xiangyu, Yang, Hong, Aydın, Mehtap, Alkurt, Gizem, Kim, Woonghee, Akyol, Dogukan, Zhang, Cheng, Dinler‐Doganay, Gizem, Turkez, Hasan, Shoaie, Saeed, Nielsen, Jens, Borén, Jan, Olmuscelik, Oktay, Doganay, Levent, Uhlén, Mathias, Mardinoglu, Adil
Publicado 2021

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients

por Zeybel, Mujdat, Altay, Ozlem, Arif, Muhammad, Li, Xiangyu, Yang, Hong, Fredolini, Claudia, Akyildiz, Murat, Saglam, Burcin, Gonenli, Mehmet Gokhan, Ural, Dilek, Kim, Woonghee, Schwenk, Jochen M, Zhang, Cheng, Shoaie, Saeed, Nielsen, Jens, Uhlén, Mathias, Borén, Jan, Mardinoglu, Adil
Publicado 2021

Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers

por Li, Xiangyu, Kim, Woonghee, Arif, Muhammad, Gao, Chunxia, Hober, Andreas, Kotol, David, Strandberg, Linnéa, Forsström, Björn, Sivertsson, Åsa, Oksvold, Per, Turkez, Hasan, Grøtli, Morten, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Boren, Jan, Nielsen, Jens, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Publicado 2021

Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

por Zhang, Cheng, Shi, Mengnan, Kim, Woonghee, Arif, Muhammad, Klevstig, Martina, Li, Xiangyu, Yang, Hong, Bayram, Cemil, Bolat, Ismail, Tozlu, Özlem Özdemir, Hacımuftuoglu, Ahmet, Yıldırım, Serkan, Sebhaoui, Jihad, Iqbal, Shazia, Wei, Yongjun, Shi, Xiaojing, Nielsen, Jens, Turkez, Hasan, Uhlen, Mathias, Boren, Jan, Mardinoglu, Adil
Publicado 2022

Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

por Battisti, Umberto Maria, Gao, Chunixa, Akladios, Fady, Kim, Woonghee, Yang, Hong, Bayram, Cemil, Bolat, Ismail, Kiliclioglu, Metin, Yuksel, Nursena, Tozlu, Ozlem Ozdemir, Zhang, Cheng, Sebhaoui, Jihad, Iqbal, Shazia, Shoaie, Saeed, Hacimuftuoglu, Ahmet, Yildirim, Serkan, Turkez, Hasan, Uhlen, Mathias, Boren, Jan, Mardinoglu, Adil, Grøtli, Morten
Publicado 2023

The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non‐alcoholic fatty liver disease

por Zhang, Cheng, Bjornson, Elias, Arif, Muhammad, Tebani, Abdellah, Lovric, Alen, Benfeitas, Rui, Ozcan, Mehmet, Juszczak, Kajetan, Kim, Woonghee, Kim, Jung Tae, Bidkhori, Gholamreza, Ståhlman, Marcus, Bergh, Per‐Olof, Adiels, Martin, Turkez, Hasan, Taskinen, Marja‐Riitta, Bosley, Jim, Marschall, Hanns‐Ulrich, Nielsen, Jens, Uhlén, Mathias, Borén, Jan, Mardinoglu, Adil
Publicado 2020