Long-term administration of CU06-1004 ameliorates cerebrovascular aging and BBB injury in aging mouse model

por Kim, Hyejeong, Noh, Minyoung, Zhang, Haiying, Kim, Yeomyeong, Park, Songyi, Park, Jeongeun, Kwon, Young-Guen
Publicado 2023

CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation

por Kim, Yeomyeong, Lee, Sungwoon, Zhang, Haiying, Lee, Sunghye, Kim, Hyejeong, Kim, Yeaji, Won, Moo-Ho, Kim, Young-Myeong, Kwon, Young-Guen
Publicado 2020

MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells

por Kim, Hyejeong, Ko, Yeongrim, Park, Hyojin, Zhang, Haiying, Jeong, Yoonjeong, Kim, Yeomyeong, Noh, Minyoung, Park, Songyi, Kim, Young-Myeong, Kwon, Young-Guen
Publicado 2019

Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury

por Kim, Yeomyeong, Bae, Cho-Rong, Kim, Dongyeop, Kim, Hyejeong, Lee, Sunghye, Zhang, Haiying, Noh, Minyoung, Kim, Young-Myeong, Mochizuki, Naoki, Kwon, Young-Guen
Publicado 2023

A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway

por Park, Jeongeun, Zhang, Haiying, Kwak, Hyun Jung, Gadhe, Changdev Gorakshnath, Kim, Yeomyeong, Kim, Hyejeong, Noh, Minyoung, Shin, Dongyun, Ha, Sang-Jun, Kwon, Young-Guen
Publicado 2023

CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

por Zhang, Haiying, Kim, Hyeok, Park, Bong Woo, Noh, Minyoung, Kim, Yeomyeong, Park, Jeongeun, Park, Jae-Hyun, Kim, Jin-Ju, Sim, Woo-Sup, Ban, Kiwon, Park, Hun-Jun, Kwon, Young-Guen
Publicado 2022