A Statistical Interaction between Circumsporozoite Protein-Specific T Cell and Antibody Responses and Risk of Clinical Malaria Episodes following Vaccination with RTS,S/AS01E

por Ndungu, Francis M., Mwacharo, Jedidah, Kimani, Domtila, Kai, Oscar, Moris, Philippe, Jongert, Erik, Vekemans, Johan, Olotu, Ally, Bejon, Philip
Publicado 2012

Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response

por Kapulu, Melissa C., Kimani, Domtila, Njuguna, Patricia, Hamaluba, Mainga, Otieno, Edward, Kimathi, Rinter, Tuju, James, Sim, B. Kim Lee
Publicado 2022

Lack of Avidity Maturation of Merozoite Antigen-Specific Antibodies with Increasing Exposure to Plasmodium falciparum amongst Children and Adults Exposed to Endemic Malaria in Keny...

por Ibison, Frances, Olotu, Ally, Muema, Daniel M., Mwacharo, Jedida, Ohuma, Eric, Kimani, Domtila, Marsh, Kevin, Bejon, Philip, Ndungu, Francis M.
Publicado 2012

Safety and PCR monitoring in 161 semi-immune Kenyan adults following controlled human malaria infection

por Kapulu, Melissa C., Njuguna, Patricia, Hamaluba, Mainga, Kimani, Domtila, Ngoi, Joyce M., Musembi, Janet, Ngoto, Omar, Otieno, Edward, Billingsley, Peter F.
Publicado 2021

CD4(+) T Cell Responses to the Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Mild Malaria

por Gitau, Evelyn N., Tuju, James, Karanja, Henry, Stevenson, Liz, Requena, Pilar, Kimani, Eva, Olotu, Ally, Kimani, Domtila, Marsh, Kevin, Bull, Peter, Urban, Britta C.
Publicado 2014

Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction

por Mogeni, Polycarp, Williams, Thomas N, Omedo, Irene, Kimani, Domtila, Ngoi, Joyce M, Mwacharo, Jedida, Morter, Richard, Nyundo, Christopher, Wambua, Juliana, Nyangweso, George, Kapulu, Melissa, Fegan, Gregory, Bejon, Philip
Publicado 2017

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01(E) and Protection against P falciparum Clinical Malaria

por Olotu, Ally, Moris, Philippe, Mwacharo, Jedidah, Vekemans, Johan, Kimani, Domtila, Janssens, Michel, Kai, Oscar, Jongert, Erik, Lievens, Marc, Leach, Amanda, Villafana, Tonya, Savarese, Barbara, Marsh, Kevin, Cohen, Joe, Bejon, Philip
Publicado 2011

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural ex...

por Abdi, Abdirahman I., Hodgson, Susanne H., Muthui, Michelle K., Kivisi, Cheryl A., Kamuyu, Gathoni, Kimani, Domtila, Hoffman, Stephen L., Juma, Elizabeth, Ogutu, Bernhards, Draper, Simon J., Osier, Faith, Bejon, Philip, Marsh, Kevin, Bull, Peter C.
Publicado 2017

Controlled human malaria infection in Kenyan adults: A safe model that could accelerate assessment of novel drugs and vaccines in malaria endemic populations

por Hodgson, Susanne, Juma, Elizabeth, Salim, Amina, Magiri, Charles, Kimani, Domtila, Njenga, Daniel, Muia, Alfred, Cole, Andrew, Ogwang, Caroline, Billingsley, Peter, James, Eric, Sim, Kim Lee, Rampling, Thomas, Hill, Adrian, Osier, Faith, Draper, Simon, Bejon, Philip, Hoffman, Stephen, Ogutu, Bernhards, Marsh, Kevin
Publicado 2014

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

por Sheehy, Susanne H., Spencer, Alexandra J., Douglas, Alexander D., Sim, B. Kim Lee, Longley, Rhea J., Edwards, Nick J., Poulton, Ian D., Kimani, Domtila, Williams, Andrew R., Anagnostou, Nicholas A., Roberts, Rachel, Kerridge, Simon, Voysey, Merryn, James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Lawrie, Alison M., Hoffman, Stephen L., Hill, Adrian V. S.
Publicado 2013

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

por Hodgson, Susanne H, Douglas, Alexander D, Edwards, Nick J, Kimani, Domtila, Elias, Sean C, Chang, Ming, Daza, Glenda, Seilie, Annette M, Magiri, Charles, Muia, Alfred, Juma, Elizabeth A, Cole, Andrew O, Rampling, Thomas W, Anagnostou, Nicholas A, Gilbert, Sarah C, Hoffman, Stephen L, Draper, Simon J, Bejon, Philip, Ogutu, Bernhards, Marsh, Kevin, Hill, Adrian VS, Murphy, Sean C
Publicado 2015

Repeated clinical malaria episodes are associated with modification of the immune system in children

por Bediako, Yaw, Adams, Rhys, Reid, Adam J., Valletta, John Joseph, Ndungu, Francis M., Sodenkamp, Jan, Mwacharo, Jedidah, Ngoi, Joyce Mwongeli, Kimani, Domtila, Kai, Oscar, Wambua, Juliana, Nyangweso, George, de Villiers, Etienne P., Sanders, Mandy, Lotkowska, Magda Ewa, Lin, Jing-Wen, Manni, Sarah, Addy, John W. G., Recker, Mario, Newbold, Chris, Berriman, Matthew, Bejon, Philip, Marsh, Kevin, Langhorne, Jean
Publicado 2019

Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Ken...

por Ogwang, Caroline, Afolabi, Muhammed, Kimani, Domtila, Jagne, Ya Jankey, Sheehy, Susanne H., Bliss, Carly M., Duncan, Christopher J. A., Collins, Katharine A., Garcia Knight, Miguel A., Kimani, Eva, Anagnostou, Nicholas A., Berrie, Eleanor, Moyle, Sarah, Gilbert, Sarah C., Spencer, Alexandra J., Soipei, Peninah, Mueller, Jenny, Okebe, Joseph, Colloca, Stefano, Cortese, Riccardo, Viebig, Nicola K., Roberts, Rachel, Gantlett, Katherine, Lawrie, Alison M., Nicosia, Alfredo, Imoukhuede, Egeruan B., Bejon, Philip, Urban, Britta C., Flanagan, Katie L., Ewer, Katie J., Chilengi, Roma, Hill, Adrian V. S., Bojang, Kalifa
Publicado 2013

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injec...

por Hodgson, Susanne H., Juma, Elizabeth, Salim, Amina, Magiri, Charles, Kimani, Domtila, Njenga, Daniel, Muia, Alfred, Cole, Andrew O., Ogwang, Caroline, Awuondo, Ken, Lowe, Brett, Munene, Marianne, Billingsley, Peter F., James, Eric R., Gunasekera, Anusha, Sim, B. Kim L., Njuguna, Patricia, Rampling, Thomas W., Richman, Adam, Abebe, Yonas, Kamuyu, Gathoni, Muthui, Michelle, Elias, Sean C., Molyneux, Sassy, Gerry, Stephen, Macharia, Alex, Williams, Thomas N., Bull, Peter C., Hill, Adrian V. S., Osier, Faith H., Draper, Simon J., Bejon, Philip, Hoffman, Stephen L., Ogutu, Bernhards, Marsh, Kevin
Publicado 2014

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast

por Agoti, Charles N., Mutunga, Martin, Lambisia, Arnold W., Kimani, Domtila, Cheruiyot, Robinson, Kiyuka, Patience, Lewa, Clement, Gicheru, Elijah, Tendwa, Metrine, Said Mohammed, Khadija, Osoti, Victor, Makale, Johnstone, Tawa, Brian, Odundo, Calleb, Cheruiyot, Wesley, Nyamu, Wilfred, Gumbi, Wilson, Mwacharo, Jedidah, Nyamako, Lydia, Otieno, Edward, Amadi, David, Thoya, Janet, Karani, Angela, Mugo, Daisy, Musyoki, Jennifer, Gumba, Horace, Mwarumba, Salim, M. Gichuki, Bonface, Njuguna, Susan, Riako, Debra, Mutua, Shadrack, Gitonga, John N., Sein, Yiakon, Bartilol, Brian, Mwangi, Shaban J., O. Omuoyo, Donwilliams, M. Morobe, John, de Laurent, Zaydah R., Bejon, Philip, Ochola-Oyier, Lynette Isabella, Tsofa, Benjamin
Publicado 2021

An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams

por Mohammed, Khadija Said, de Laurent, Zaydah R., Omuoyo, Donwilliams O., Lewa, Clement, Gicheru, Elijah, Cheruiyot, Robinson, Bartilol, Brian, Mutua, Shadrack, Musyoki, Jennifer, Gumba, Horace, Mwacharo, Jedidah, Riako, Debra, Mwangi, Shaban J., Gichuki, Bonface M., Nyamako, Lydia, Karani, Angela, Karanja, Henry, Mugo, Daisy, Gitonga, John N., Njuguna, Susan, Gumbi, Wilson, Tawa, Brian, Tendwa, Metrine, Cheruiyot, Wesley, Sein, Yiakon, Nyambu, John K., Patta, Shem O., Thani, Thani Suleiman, Maitha, Eric K., Kitole, Benson, Mwakinangu, Mohamed S., Muslih, Barke S., Otieno, John Ochieng, Nyiro, Joyce U., Kiyuka, Patience, Ndwiga, Leonard, Wamae, Kevin, Kimani, Domtila, Makale, Johnstone, Morobe, John Mwita, Osoti, Victor, Lambisia, Arnold W., Odundo, Calleb, Mwarumba, Salim, Mutunga, Martin, Bejon, Philip, Tsofa, Benjamin, Agoti, Charles N., Ochola-Oyier, Lynette Isabella
Publicado 2022