Sensitive measurement of single-nucleotide polymorphism-induced changes of RNA conformation: application to disease studies

por Salari, Raheleh, Kimchi-Sarfaty, Chava, Gottesman, Michael M., Przytycka, Teresa M.
Publicado 2013

In silico methods for predicting functional synonymous variants

por Lin, Brian C., Katneni, Upendra, Jankowska, Katarzyna I., Meyer, Douglas, Kimchi-Sarfaty, Chava
Publicado 2023

In Silico Evaluation of Cyclophilin Inhibitors as Potential Treatment for SARS-CoV-2

por Laurie, Kyle, Holcomb, David, Kames, Jacob, Komar, Anton A, DiCuccio, Michael, Ibla, Juan C, Kimchi-Sarfaty, Chava
Publicado 2021

A new and updated resource for codon usage tables

por Athey, John, Alexaki, Aikaterini, Osipova, Ekaterina, Rostovtsev, Alexandre, Santana-Quintero, Luis V., Katneni, Upendra, Simonyan, Vahan, Kimchi-Sarfaty, Chava
Publicado 2017

Recent advances in (therapeutic protein) drug development

por Lagassé, H.A. Daniel, Alexaki, Aikaterini, Simhadri, Vijaya L., Katagiri, Nobuko H., Jankowski, Wojciech, Sauna, Zuben E., Kimchi-Sarfaty, Chava
Publicado 2017

Inhibition of Multidrug Resistance by SV40 Pseudovirion Delivery of an Antigene Peptide Nucleic Acid (PNA) in Cultured Cells

por Macadangdang, Benjamin, Zhang, Ning, Lund, Paul E., Marple, Andrew H., Okabe, Mitsunori, Gottesman, Michael M., Appella, Daniel H., Kimchi-Sarfaty, Chava
Publicado 2011

Analysis of 3.5 million SARS-CoV-2 sequences reveals unique mutational trends with consistent nucleotide and codon frequencies

por Fumagalli, Sarah E., Padhiar, Nigam H., Meyer, Douglas, Katneni, Upendra, Bar, Haim, DiCuccio, Michael, Komar, Anton A., Kimchi-Sarfaty, Chava
Publicado 2023

Splicing dysregulation contributes to the pathogenicity of several F9 exonic point variants

por Katneni, Upendra K., Liss, Aaron, Holcomb, David, Katagiri, Nobuko H., Hunt, Ryan, Bar, Haim, Ismail, Amra, Komar, Anton A., Kimchi‐Sarfaty, Chava
Publicado 2019

Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design

por Kames, Jacob, Holcomb, David D., Kimchi, Ofer, DiCuccio, Michael, Hamasaki-Katagiri, Nobuko, Wang, Tony, Komar, Anton A., Alexaki, Aikaterini, Kimchi-Sarfaty, Chava
Publicado 2020

Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design

por Kames, Jacob, Holcomb, David D., Kimchi, Ofer, DiCuccio, Michael, Hamasaki-Katagiri, Nobuko, Wang, Tony, Komar, Anton A., Alexaki, Aikaterini, Kimchi-Sarfaty, Chava
Publicado 2020

Gene variants of coagulation related proteins that interact with SARS-CoV-2

por Holcomb, David, Alexaki, Aikaterini, Hernandez, Nancy, Hunt, Ryan, Laurie, Kyle, Kames, Jacob, Hamasaki-Katagiri, Nobuko, Komar, Anton A., DiCuccio, Michael, Kimchi-Sarfaty, Chava
Publicado 2021

Protocol to identify host-viral protein interactions between coagulation-related proteins and their genetic variants with SARS-CoV-2 proteins

por Holcomb, David D., Jankowska, Katarzyna I., Hernandez, Nancy, Laurie, Kyle, Kames, Jacob, Hamasaki-Katagiri, Nobuko, Komar, Anton A., DiCuccio, Michael, Kimchi-Sarfaty, Chava
Publicado 2022

Synonymous ADAMTS13 variants impact molecular characteristics and contribute to variability in active protein abundance

por Jankowska, Katarzyna I., Meyer, Douglas, Holcomb, David D., Kames, Jacob, Hamasaki-Katagiri, Nobuko, Katneni, Upendra K., Hunt, Ryan C., Ibla, Juan C., Kimchi-Sarfaty, Chava
Publicado 2022

Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene

por Sarachana, Tewarit, Dahiya, Neetu, Simhadri, Vijaya L., Pandey, Gouri Shankar, Saini, Surbhi, Guelcher, Christine, Guerrera, Michael F., Kimchi-Sarfaty, Chava, Sauna, Zuben E., Atreya, Chintamani D.
Publicado 2015

Characterization of Conformation-Sensitive Antibodies to ADAMTS13, the von Willebrand Cleavage Protease

por Sauna, Zuben E., Okunji, Chinyere, Hunt, Ryan C., Gupta, Tanvi, Allen, Courtni E., Plum, Elizabeth, Blaisdell, Adam, Grigoryan, Vahan, S, Geetha, Fathke, Robert, Soejima, Kenji, Kimchi-Sarfaty, Chava
Publicado 2009

Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

por Meyer, Douglas, Kames, Jacob, Bar, Haim, Komar, Anton A., Alexaki, Aikaterini, Ibla, Juan, Hunt, Ryan C., Santana-Quintero, Luis V., Golikov, Anton, DiCuccio, Michael, Kimchi-Sarfaty, Chava
Publicado 2021

Ribosome profiling of HEK293T cells overexpressing codon optimized coagulation factor IX

por Alexaki, Aikaterini, Kames, Jacob, Hettiarachchi, Gaya K., Athey, John C., Katneni, Upendra K., Hunt, Ryan C., Hamasaki-Katagiri, Nobuko, Holcomb, David D., DiCuccio, Michael, Bar, Haim, Komar, Anton A., Kimchi-Sarfaty, Chava
Publicado 2020

Synthesis of FVIII in Hemophilia-A patients with the intron-22-inversion may modulate immunogenicity

por Pandey, Gouri Shankar, Yanover, Chen, Miller-Jenkins, Lisa M., Garfield, Susan, Cole, Shelley A., Curran, Joanne E., Moses, Eric K., Rydz, Natalia, Simhadri, Vijaya, Kimchi-Sarfaty, Chava, Lillicrap, David, Viel, Kevin, Przytycka, Teresa M., Pierce, Glenn F., Howard, Tom E., Sauna, Zuben E.
Publicado 2013

A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity

por Hunt, Ryan, Hettiarachchi, Gaya, Katneni, Upendra, Hernandez, Nancy, Holcomb, David, Kames, Jacob, Alnifaidy, Redab, Lin, Brian, Hamasaki-Katagiri, Nobuko, Wesley, Aaron, Kafri, Tal, Morris, Christina, Bouché, Laura, Panico, Maria, Schiller, Tal, Ibla, Juan, Bar, Haim, Ismail, Amra, Morris, Howard, Komar, Anton, Kimchi-Sarfaty, Chava
Publicado 2019

Characterization of Coding Synonymous and Non-Synonymous Variants in ADAMTS13 Using Ex Vivo and In Silico Approaches

por Edwards, Nathan C., Hing, Zachary A., Perry, Avital, Blaisdell, Adam, Kopelman, David B., Fathke, Robert, Plum, William, Newell, Jordan, Allen, Courtni E., S., Geetha, Shapiro, Aaron, Okunji, Chinyere, Kosti, Idit, Shomron, Noam, Grigoryan, Vahan, Przytycka, Teresa M., Sauna, Zuben E., Salari, Raheleh, Mandel-Gutfreund, Yael, Komar, Anton A., Kimchi-Sarfaty, Chava
Publicado 2012