IL-7 signaling must be intermittent, not continuous, during CD8 T cell homeostasis to promote cell survival instead of cell death

por Kimura, Motoko Y., Pobezinsky, Leonid A., Guinter, Terry, Thomas, Julien, Adams, Anthony, Park, Jung-Hyun, Tai, Xuguang, Singer, Alfred
Publicado 2012

Regulation of T helper type 2 cell differentiation by murine Schnurri-2

por Kimura, Motoko Y., Hosokawa, Hiroyuki, Yamashita, Masakatsu, Hasegawa, Akihiro, Iwamura, Chiaki, Watarai, Hiroshi, Taniguchi, Masaru, Takagi, Tsuyoshi, Ishii, Shunsuke, Nakayama, Toshinori
Publicado 2005

Survival of Naïve T Cells Requires the Expression of Let-7 miRNAs

por Pobezinskaya, Elena L., Wells, Alexandria C., Angelou, Constance C., Fagerberg, Eric, Aral, Esengul, Iverson, Elizabeth, Kimura, Motoko Y., Pobezinsky, Leonid A.
Publicado 2019

Clinical and Histological Effects of Partial Blood Flow Impairment in Vascularized Lymph Node Transfer

por Akita, Shinsuke, Ikehara, Yuzuru, Arai, Minami, Tokumoto, Hideki, Yamaji, Yoshihisa, Azuma, Kazuhiko, Kubota, Yoshitaka, Haneishi, Hideaki, Kimura, Motoko Y., Mitsukawa, Nobuyuki
Publicado 2022

Myosin Light Chain 9/12 Regulates the Pathogenesis of Inflammatory Bowel Disease

por Yokoyama, Masaya, Kimura, Motoko Y., Ito, Toshihiro, Hayashizaki, Koji, Endo, Yukihiro, Wang, Yangsong, Yagi, Ryoji, Nakagawa, Tomoo, Kato, Naoya, Matsubara, Hisahiro, Nakayama, Toshinori
Publicado 2021

CD69 prevents PLZF(hi) innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation

por Kimura, Motoko Y., Igi, Akemi, Hayashizaki, Koji, Mita, Yukiyoshi, Shinzawa, Miho, Kadakia, Tejas, Endo, Yukihiro, Ogawa, Satomi, Yagi, Ryoji, Motohashi, Shinichiro, Singer, Alfred, Nakayama, Toshinori
Publicado 2018

IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation

por Sarkar, Murshed H., Yagi, Ryoji, Endo, Yukihiro, Koyama-Nasu, Ryo, Wang, Yangsong, Hasegawa, Ichita, Ito, Toshihiro, Junttila, Ilkka S., Zhu, Jinfang, Kimura, Motoko Y., Nakayama, Toshinori
Publicado 2021

Let-7 miRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function

por Pobezinsky, Leonid A., Etzensperger, Ruth, Jeurling, Susanna, Alag, Amala, Kadakia, Tejas, McCaughtry, Tom M., Kimura, Motoko Y., Sharrow, Susan O., Guinter, Terry I., Feigenbaum, Lionel, Singer, Alfred
Publicado 2015

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation

por Suzuki, Akane S., Yagi, Ryoji, Kimura, Motoko Y., Iwamura, Chiaki, Shinoda, Kenta, Onodera, Atsushi, Hirahara, Kiyoshi, Tumes, Damon J., Koyama-Nasu, Ryo, Iismaa, Siiri E., Graham, Robert M., Motohashi, Shinichiro, Nakayama, Toshinori
Publicado 2020

Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d‐independent manner

por Aoki, Takahiro, Takami, Mariko, Takatani, Tomozumi, Motoyoshi, Kiwamu, Ishii, Ayana, Hara, Ayaka, Toyoda, Takahide, Okada, Reona, Hino, Moeko, Koyama‐Nasu, Ryo, Kiuchi, Masahiro, Hirahara, Kiyoshi, Kimura, Motoko Y., Nakayama, Toshinori, Shimojo, Naoki, Motohashi, Shinichiro
Publicado 2020

Differentiation of Pathogenic Th17 Cells Is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis

por Angelou, Constance C., Wells, Alexandria C., Vijayaraghavan, Jyothi, Dougan, Carey E., Lawlor, Rebecca, Iverson, Elizabeth, Lazarevic, Vanja, Kimura, Motoko Y., Peyton, Shelly R., Minter, Lisa M., Osborne, Barbara A., Pobezinskaya, Elena L., Pobezinsky, Leonid A.
Publicado 2020

Increased Myosin light chain 9 expression during Kawasaki disease vasculitis

por Kobayashi, Hironobu, Kimura, Motoko Y., Hasegawa, Ichita, Suganuma, Eisuke, Ikehara, Yuzuru, Azuma, Kazuhiko, Ito, Toshihiro, Ebata, Ryota, Kurashima, Yosuke, Kawasaki, Yohei, Shiko, Yuki, Saito, Naoki, Iwase, Hirotaro, Lee, Youngho, Noval Rivas, Magali, Arditi, Moshe, Zuka, Masahiko, Hamada, Hiromichi, Nakayama, Toshinori
Publicado 2023

Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity

por Iwamura, Chiaki, Hirahara, Kiyoshi, Kiuchi, Masahiro, Ikehara, Sanae, Azuma, Kazuhiko, Shimada, Tadanaga, Kuriyama, Sachiko, Ohki, Syota, Yamamoto, Emiri, Inaba, Yosuke, Shiko, Yuki, Aoki, Ami, Kokubo, Kota, Hirasawa, Rui, Hishiya, Takahisa, Tsuji, Kaori, Nagaoka, Tetsutaro, Ishikawa, Satoru, Kojima, Akira, Mito, Haruki, Hase, Ryota, Kasahara, Yasunori, Kuriyama, Naohide, Tsukamoto, Tetsuya, Nakamura, Sukeyuki, Urushibara, Takashi, Kaneda, Satoru, Sakao, Seiichiro, Tobiume, Minoru, Suzuki, Yoshio, Tsujiwaki, Mitsuhiro, Kubo, Terufumi, Hasegawa, Tadashi, Nakase, Hiroshi, Nishida, Osamu, Takahashi, Kazuhisa, Baba, Komei, Iizumi, Yoko, Okazaki, Toshiya, Kimura, Motoko Y., Yoshino, Ichiro, Igari, Hidetoshi, Nakajima, Hiroshi, Suzuki, Takuji, Hanaoka, Hideki, Nakada, Taka-aki, Ikehara, Yuzuru, Yokote, Koutaro, Nakayama, Toshinori
Publicado 2022