The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma

por Kinahan, Cristina, Mangone, Michael A., Scotto, Luigi, Visentin, Michele, Marchi, Enrica, Cho, Hearn Jay, O’Connor, Owen A.
Publicado 2020

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest

por Scotto, Luigi, Serrano, Xavier J., Zullo, Kelly, Kinahan, Cristina, Deng, Changchun, Sawas, Ahmed, Bates, Susan, O’Connor, Owen A.
Publicado 2020

Generation of pralatrexate resistant T‐cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers

por Scotto, Luigi, Kinahan, Cristina, Casadei, Beatrice, Mangone, Michael, Douglass, Eugene, Murty, Vundavalli V., Marchi, Enrica, Ma, Helen, George, Changchun, Montanari, Francesca, Califano, Andrea, O'Connor, Owen A.
Publicado 2020

Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways

por Scotto, Luigi, Kinahan, Cristina, Douglass, Eugene, Deng, Changchun, Safari, Maryam, Casadei, Beatrice, Marchi, Enrica, Lue, Jennifer K., Montanari, Francesca, Falchi, Lorenzo, Qiao, Changhong, Renu, Nandakumar, Bates, Susan E., Califano, Andrea, O'Connor, Owen A.
Publicado 2021