New Vaccine Design and Delivery Technologies

por Kanekiyo, Masaru, Ellis, Daniel, King, Neil P
Publicado 2019

Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery

por Olshefsky, Audrey, Richardson, Christian, Pun, Suzie H., King, Neil P.
Publicado 2022

Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials

por Wargacki, Adam J., Wörner, Tobias P., van de Waterbeemd, Michiel, Ellis, Daniel, Heck, Albert J. R., King, Neil P.
Publicado 2021

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

por Read, Benjamin J., Won, Lori, Kraft, John C., Sappington, Isaac, Aung, Aereas, Wu, Shengwei, Bals, Julia, Chen, Chengbo, Lee, Kelly K., Lingwood, Daniel, King, Neil P., Irvine, Darrell J.
Publicado 2022

Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus

por Lee, Jimin, Zepeda, Samantha K., Park, Young-Jun, Taylor, Ashley L., Quispe, Joel, Stewart, Cameron, Leaf, Elizabeth M., Treichel, Catherine, Corti, Davide, King, Neil P., Starr, Tyler N., Veesler, David
Publicado 2023

Hierarchical design of pseudosymmetric protein nanoparticles

por Dowling, Quinton M., Park, Young-Jun, Gerstenmaier, Neil, Yang, Erin C., Wargacki, Adam, Hsia, Yang, Fries, Chelsea N., Ravichandran, Rashmi, Walkey, Carl, Burrell, Anika, Veesler, David, Baker, David, King, Neil P.
Publicado 2023

Hierarchical design of pseudosymmetric protein nanoparticles

por Dowling, Quinton M., Park, Young-Jun, Gerstenmaier, Neil, Yang, Erin C., Wargacki, Adam, Hsia, Yang, Fries, Chelsea N., Ravichandran, Rashmi, Walkey, Carl, Burrell, Anika, Veesler, David, Baker, David, King, Neil P.
Publicado 2023

Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock

por Sheffler, William, Yang, Erin C., Dowling, Quinton, Hsia, Yang, Fries, Chelsea N., Stanislaw, Jenna, Langowski, Mark D., Brandys, Marisa, Li, Zhe, Skotheim, Rebecca, Borst, Andrew J., Khmelinskaia, Alena, King, Neil P., Baker, David
Publicado 2023

Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever

por Lacasta, Anna, Kim, Hyung Chan, Kepl, Elizabeth, Gachogo, Rachael, Chege, Naomi, Ojuok, Rose, Muriuki, Charity, Mwalimu, Stephen, Touboul, Gilad, Stiber, Ariel, Poole, Elizabeth Jane, Ndiwa, Nicholas, Fiala, Brooke, King, Neil P., Nene, Vishvanath
Publicado 2023

Design of a hyperstable 60-subunit protein icosahedron

por Hsia, Yang, Bale, Jacob B., Gonen, Shane, Shi, Dan, Sheffler, William, Fong, Kimberly K., Nattermann, Una, Xu, Chunfu, Huang, Po-Ssu, Ravichandran, Rashmi, Yi, Sue, Davis, Trisha N., Gonen, Tamir, King, Neil P., Baker, David
Publicado 2016

Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samples

por Larsen, Sasha E., Berube, Bryan J., Pecor, Tiffany, Cross, Evan, Brown, Bryan P., Williams, Brittany, Johnson, Emma, Qu, Pingping, Carter, Lauren, Wrenn, Samuel, Kepl, Elizabeth, Sydeman, Claire, King, Neil P., Baldwin, Susan L., Coler, Rhea N.
Publicado 2021

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

por Starr, Tyler N., Greaney, Allison J., Hilton, Sarah K., Ellis, Daniel, Crawford, Katharine H.D., Dingens, Adam S., Navarro, Mary Jane, Bowen, John E., Tortorici, M. Alejandra, Walls, Alexandra C., King, Neil P., Veesler, David, Bloom, Jesse D.
Publicado 2020

Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samples

por Larsen, Sasha E., Berube, Bryan J., Pecor, Tiffany, Cross, Evan, Brown, Bryan P., Williams, Brittany D., Johnson, Emma, Qu, Pingping, Carter, Lauren, Wrenn, Samuel, Kepl, Elizabeth, Sydeman, Claire, King, Neil P., Baldwin, Susan L., Coler, Rhea N.
Publicado 2021

Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays

por Crawford, Katharine H. D., Eguia, Rachel, Dingens, Adam S., Loes, Andrea N., Malone, Keara D., Wolf, Caitlin R., Chu, Helen Y., Tortorici, M. Alejandra, Veesler, David, Murphy, Michael, Pettie, Deleah, King, Neil P., Balazs, Alejandro B., Bloom, Jesse D.
Publicado 2020

Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection

por Crawford, Katharine H D, Dingens, Adam S, Eguia, Rachel, Wolf, Caitlin R, Wilcox, Naomi, Logue, Jennifer K, Shuey, Kiel, Casto, Amanda M, Fiala, Brooke, Wrenn, Samuel, Pettie, Deleah, King, Neil P, Greninger, Alexander L, Chu, Helen Y, Bloom, Jesse D
Publicado 2020

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

por Glaros, Vassilis, Rauschmeier, René, Artemov, Artem V., Reinhardt, Annika, Ols, Sebastian, Emmanouilidi, Aikaterini, Gustafsson, Charlotte, You, Yuanyuan, Mirabello, Claudio, Björklund, Åsa K., Perez, Laurent, King, Neil P., Månsson, Robert, Angeletti, Davide, Loré, Karin, Adameyko, Igor, Busslinger, Meinrad, Kreslavsky, Taras
Publicado 2021

Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein

por Tortorici, M. Alejandra, Walls, Alexandra C., Joshi, Anshu, Park, Young-Jun, Eguia, Rachel T., Miranda, Marcos C., Kepl, Elizabeth, Dosey, Annie, Stevens-Ayers, Terry, Boeckh, Michael J., Telenti, Amalio, Lanzavecchia, Antonio, King, Neil P., Corti, Davide, Bloom, Jesse D., Veesler, David
Publicado 2022

Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region

por Schoeder, Clara T., Gilchuk, Pavlo, Sangha, Amandeep K., Ledwitch, Kaitlyn V., Malherbe, Delphine C., Zhang, Xuan, Binshtein, Elad, Williamson, Lauren E., Martina, Cristina E., Dong, Jinhui, Armstrong, Erica, Sutton, Rachel, Nargi, Rachel, Rodriguez, Jessica, Kuzmina, Natalia, Fiala, Brooke, King, Neil P., Bukreyev, Alexander, Crowe, James E., Meiler, Jens
Publicado 2022

Multimeric antibodies from antigen-specific human IgM(+) memory B cells restrict Plasmodium parasites

por Thouvenel, Christopher D., Fontana, Mary F., Netland, Jason, Krishnamurty, Akshay T., Takehara, Kennidy K., Chen, Yu, Singh, Suruchi, Miura, Kazutoyo, Keitany, Gladys J., Lynch, Eric M., Portugal, Silvia, Miranda, Marcos C., King, Neil P., Kollman, Justin M., Crompton, Peter D., Long, Carole A., Pancera, Marie, Rawlings, David J., Pepper, Marion
Publicado 2021

Process development of a SARS-CoV-2 nanoparticle vaccine

por Martinez-Cano, Diandra, Ravichandran, Rashmi, Le, Huong, Wong, H. Edward, Jagannathan, Bharat, Liu, Erik J., Bailey, William, Yang, Jane, Matthies, Kelli, Barkhordarian, Hedieh, Shah, Bhavana, Srinivasan, Nithya, Zhang, Jun, Hsu, Angel, Wypych, Jette, Stevens, Jennitte, Piedmonte, Deirdre Murphy, Miranda, Les P., Carter, Lauren, Murphy, Michael, King, Neil P., Soice, Neil
Publicado 2023