Electron in action

por Kinney, Steven
Publicado 2019

Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461

por Masud, Tehmina, Soong, Charles, Xu, Hong, Biele, Justina, Bjornson, Saelin, McKinney, Steven, Aparicio, Samuel
Publicado 2021

Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models

por Funnell, Tyler, Zhang, Allen W., Grewal, Diljot, McKinney, Steven, Bashashati, Ali, Wang, Yi Kan, Shah, Sohrab P.
Publicado 2019

Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development

por Oloumi, Arusha, Maidan, Mykola, Lock, Frances E, Tearle, Howard, McKinney, Steven, Muller, William J, Aparicio, Samuel AJR, Dedhar, Shoukat
Publicado 2010

A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation

por Burleigh, Angela, McKinney, Steven, Brimhall, Jazmine, Yap, Damian, Eirew, Peter, Poon, Steven, Ng, Viola, Wan, Adrian, Prentice, Leah, Annab, Lois, Barrett, J Carl, Caldas, Carlos, Eaves, Connie, Aparicio, Samuel
Publicado 2015

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

por Prentice, Leah M, Klausen, Christian, Kalloger, Steve, Köbel, Martin, McKinney, Steven, Santos, Jennifer L, Kenney, Challayne, Mehl, Erika, Gilks, C Blake, Leung, Peter, Swenerton, Ken, Huntsman, David G, Aparicio, Samuel AJ
Publicado 2007

Mll5 Is Required for Normal Spermatogenesis

por Yap, Damian B., Walker, David C., Prentice, Leah M., McKinney, Steven, Turashvili, Gulisa, Mooslehner-Allen, Katrin, de Algara, Teresa Ruiz, Fee, John, de Tassigny, Xavier d'Anglemont, Colledge, William H., Aparicio, Samuel
Publicado 2011

Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell...

por Leung, Ada W. Y., Hung, Stacy S., Backstrom, Ian, Ricaurte, Daniel, Kwok, Brian, Poon, Steven, McKinney, Steven, Segovia, Romulo, Rawji, Jenna, Qadir, Mohammed A., Aparicio, Samuel, Stirling, Peter C., Steidl, Christian, Bally, Marcel B.
Publicado 2016

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

por Köbel, Martin, Kalloger, Steve E, Boyd, Niki, McKinney, Steven, Mehl, Erika, Palmer, Chana, Leung, Samuel, Bowen, Nathan J, Ionescu, Diana N, Rajput, Ashish, Prentice, Leah M, Miller, Dianne, Santos, Jennifer, Swenerton, Kenneth, Gilks, C. Blake, Huntsman, David
Publicado 2008

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

por Prentice, Leah M, d'Anglemont de Tassigny, Xavier, McKinney, Steven, Ruiz de Algara, Teresa, Yap, Damian, Turashvili, Gulisa, Poon, Steven, Sutcliffe, Margaret, Allard, Pat, Burleigh, Angela, Fee, John, Huntsman, David G, Colledge, William H, Aparicio, Samuel AJ
Publicado 2011

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

por Holland, Daniel G, Burleigh, Angela, Git, Anna, Goldgraben, Mae A, Perez-Mancera, Pedro A, Chin, Suet-Feung, Hurtado, Antonio, Bruna, Alejandra, Ali, H Raza, Greenwood, Wendy, Dunning, Mark J, Samarajiwa, Shamith, Menon, Suraj, Rueda, Oscar M, Lynch, Andy G, McKinney, Steven, Ellis, Ian O, Eaves, Connie J, Carroll, Jason S, Curtis, Christina, Aparicio, Samuel, Caldas, Carlos
Publicado 2011

Accurate determination of CRISPR-mediated gene fitness in transplantable tumours

por Eirew, Peter, O’Flanagan, Ciara, Ting, Jerome, Salehi, Sohrab, Brimhall, Jazmine, Wang, Beixi, Biele, Justina, Algara, Teresa, Lee, So Ra, Hoang, Corey, Yap, Damian, McKinney, Steven, Bates, Cherie, Kong, Esther, Lai, Daniel, Beatty, Sean, Andronescu, Mirela, Zaikova, Elena, Funnell, Tyler, Ceglia, Nicholas, Chia, Stephen, Gelmon, Karen, Mar, Colin, Shah, Sohrab, Roth, Andrew, Bouchard-Côté, Alexandre, Aparicio, Samuel
Publicado 2022

Dynamics of breast cancer relapse reveal late recurring ER-positive genomic subgroups

por Rueda, Oscar M., Sammut, Stephen-John, Seoane, Jose A, Chin, Suet-Feung, Caswell-Jin, Jennifer L, Callari, Maurizio, Batra, Rajbir, Pereira, Bernard, Bruna, Alejandra, Ali, H Raza, Provenzano, Elena, Liu, Bin, Parisien, Michelle, Gillett, Cheryl, McKinney, Steven, Green, Andrew R., Murphy, Leigh, Purushotham, Arnie, Ellis, Ian O., Pharoah, Paul D., Rueda, Cristina, Aparicio, Samuel AJR, Caldas, Carlos, Curtis, Christina
Publicado 2019

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

por Vollan, Hans Kristian Moen, Rueda, Oscar M., Chin, Suet-Feung, Curtis, Christina, Turashvili, Gulisa, Shah, Sohrab, Lingjærde, Ole Christian, Yuan, Yinyin, Ng, Charlotte K., Dunning, Mark J., Dicks, Ed, Provenzano, Elena, Sammut, Stephen, McKinney, Steven, Ellis, Ian O., Pinder, Sarah, Purushotham, Arnie, Murphy, Leigh C., Kristensen, Vessela N., Brenton, James D., Pharoah, Paul D.P., Børresen-Dale, Anne-Lise, Aparicio, Samuel, Caldas, Carlos
Publicado 2014

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

por Curtis, Christina, Shah, Sohrab P., Chin, Suet-Feung, Turashvili, Gulisa, Rueda, Oscar M., Dunning, Mark J., Speed, Doug, Lynch, Andy G., Samarajiwa, Shamith, Yuan, Yinyin, Gräf, Stefan, Ha, Gavin, Haffari, Gholamreza, Bashashati, Ali, Russell, Roslin, McKinney, Steven, Langerød, Anita, Green, Andrew, Provenzano, Elena, Wishart, Gordon, Pinder, Sarah, Watson, Peter, Markowetz, Florian, Murphy, Leigh, Ellis, Ian, Purushotham, Arnie, Børresen-Dale, Anne-Lise, Brenton, James D., Tavaré, Simon, Caldas, Carlos, Aparicio, Samuel
Publicado 2012

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

por Funnell, Tyler, Tasaki, Shinya, Oloumi, Arusha, Araki, Shinsuke, Kong, Esther, Yap, Damian, Nakayama, Yusuke, Hughes, Christopher S., Cheng, S.-W. Grace, Tozaki, Hirokazu, Iwatani, Misa, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Morishita, Nao, Morishita, Daisuke, Ogasawara-Shimizu, Mari, Ohori, Momoko, Nakao, Shoichi, Karashima, Masatoshi, Sano, Masaya, Murai, Aiko, Nomura, Toshiyuki, Uchiyama, Noriko, Kawamoto, Tomohiro, Hara, Ryujiro, Nakanishi, Osamu, Shumansky, Karey, Rosner, Jamie, Wan, Adrian, McKinney, Steven, Morin, Gregg B., Nakanishi, Atsushi, Shah, Sohrab, Toyoshiba, Hiroyoshi, Aparicio, Samuel
Publicado 2017

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

por Xu, Hong, Di Antonio, Marco, McKinney, Steven, Mathew, Veena, Ho, Brandon, O'Neil, Nigel J., Santos, Nancy Dos, Silvester, Jennifer, Wei, Vivien, Garcia, Jessica, Kabeer, Farhia, Lai, Daniel, Soriano, Priscilla, Banáth, Judit, Chiu, Derek S., Yap, Damian, Le, Daniel D., Ye, Frank B., Zhang, Anni, Thu, Kelsie, Soong, John, Lin, Shu-chuan, Tsai, Angela Hsin Chin, Osako, Tomo, Algara, Teresa, Saunders, Darren N., Wong, Jason, Xian, Jian, Bally, Marcel B., Brenton, James D., Brown, Grant W., Shah, Sohrab P., Cescon, David, Mak, Tak W., Caldas, Carlos, Stirling, Peter C., Hieter, Phil, Balasubramanian, Shankar, Aparicio, Samuel
Publicado 2017

Single-cell genomic variation induced by mutational processes in cancer

por Funnell, Tyler, O’Flanagan, Ciara H., Williams, Marc J., McPherson, Andrew, McKinney, Steven, Kabeer, Farhia, Lee, Hakwoo, Salehi, Sohrab, Vázquez-García, Ignacio, Shi, Hongyu, Leventhal, Emily, Masud, Tehmina, Eirew, Peter, Yap, Damian, Zhang, Allen W., Lim, Jamie L. P., Wang, Beixi, Brimhall, Jazmine, Biele, Justina, Ting, Jerome, Au, Vinci, Van Vliet, Michael, Liu, Yi Fei, Beatty, Sean, Lai, Daniel, Pham, Jenifer, Grewal, Diljot, Abrams, Douglas, Havasov, Eliyahu, Leung, Samantha, Bojilova, Viktoria, Moore, Richard A., Rusk, Nicole, Uhlitz, Florian, Ceglia, Nicholas, Weiner, Adam C., Zaikova, Elena, Douglas, J. Maxwell, Zamarin, Dmitriy, Weigelt, Britta, Kim, Sarah H., Da Cruz Paula, Arnaud, Reis-Filho, Jorge S., Martin, Spencer D., Li, Yangguang, Xu, Hong, de Algara, Teresa Ruiz, Lee, So Ra, Llanos, Viviana Cerda, Huntsman, David G., McAlpine, Jessica N., Shah, Sohrab P., Aparicio, Samuel
Publicado 2022