Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction

por Pellegrini, Hannah, Sharpe, Elizabeth H., Liu, Guangyi, Nishiuchi, Eiko, Doerr, Nicholas, Kipp, Kevin R., Chin, Tiffany, Schimmel, Margaret F., Weimbs, Thomas
Publicado 2023

Synthetic lethality of cyclin-dependent kinase inhibitor Dinaciclib with VHL-deficiency allows for selective targeting of clear cell renal cell carcinoma

por Nelson, Luke J, Castro, Kyleen E, Xu, Binzhi, Li, Junyi, Dinh, Nguyen B, Thompson, Jordan M, Woytash, Jordan, Kipp, Kevin R, Razorenova, Olga V
Publicado 2022

Restoration of atypical protein kinase C ζ function in autosomal dominant polycystic kidney disease ameliorates disease progression

por Akbari, Masaw, West, Jonathan D., Doerr, Nicholas, Kipp, Kevin R., Marhamati, Neda, Vuong, Sabrina, Wang, Yidi, Rinschen, Markus M., Talbot, Jeffrey J., Wessely, Oliver, Weimbs, Thomas
Publicado 2022

Regulation of Polycystin-1 Function by Calmodulin Binding

por Doerr, Nicholas, Wang, Yidi, Kipp, Kevin R., Liu, Guangyi, Benza, Jesse J., Pletnev, Vladimir, Pavlov, Tengis S., Staruschenko, Alexander, Mohieldin, Ashraf M., Takahashi, Maki, Nauli, Surya M., Weimbs, Thomas
Publicado 2016