Halting coronavirus polymerase

por Kirchdoerfer, Robert N.
Publicado 2020

Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

por Kirchdoerfer, Robert N., Ward, Andrew B.
Publicado 2019

Mass spectrometric based detection of protein nucleotidylation in the RNA polymerase of SARS-CoV-2

por Conti, Brian J., Leicht, Andrew S., Kirchdoerfer, Robert N., Sussman, Michael R.
Publicado 2021

The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis

por Kirchdoerfer, Robert N., Moyer, Crystal L., Abelson, Dafna M., Saphire, Erica Ollmann
Publicado 2016

An alphacoronavirus polymerase structure reveals conserved co-factor functions

por Anderson, Thomas K., Hoferle, Peter J., Lee, Kenneth W., Coon, Joshua J., Kirchdoerfer, Robert N.
Publicado 2023

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

por Kirchdoerfer, Robert N., Bhandari, Mahesh, Martini, Olnita, Sewall, Leigh M., Bangaru, Sandhya, Yoon, Kyoung-Jin, Ward, Andrew B.
Publicado 2021

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase

por Chien, Minchen, Anderson, Thomas K., Jockusch, Steffen, Tao, Chuanjuan, Kumar, Shiv, Li, Xiaoxu, Russo, James J., Kirchdoerfer, Robert N., Ju, Jingyue
Publicado 2020

A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19

por Jockusch, Steffen, Tao, Chuanjuan, Li, Xiaoxu, Anderson, Thomas K., Chien, Minchen, Kumar, Shiv, Russo, James J., Kirchdoerfer, Robert N., Ju, Jingyue
Publicado 2020

Nucleotide analogues as inhibitors of SARS‐CoV Polymerase

por Ju, Jingyue, Li, Xiaoxu, Kumar, Shiv, Jockusch, Steffen, Chien, Minchen, Tao, Chuanjuan, Morozova, Irina, Kalachikov, Sergey, Kirchdoerfer, Robert N., Russo, James J.
Publicado 2020

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

por Kirchdoerfer, Robert N., Wang, Nianshuang, Pallesen, Jesper, Wrapp, Daniel, Turner, Hannah L., Cottrell, Christopher A., Corbett, Kizzmekia S., Graham, Barney S., McLellan, Jason S., Ward, Andrew B.
Publicado 2018

Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

por Kirchdoerfer, Robert N., Wang, Nianshuang, Pallesen, Jesper, Wrapp, Daniel, Turner, Hannah L., Cottrell, Christopher A., Corbett, Kizzmekia S., Graham, Barney S., McLellan, Jason S., Ward, Andrew B.
Publicado 2018

Pre-fusion structure of a human coronavirus spike protein

por Kirchdoerfer, Robert N., Cottrell, Christopher A., Wang, Nianshuang, Pallesen, Jesper, Yassine, Hadi M., Turner, Hannah L., Corbett, Kizzmekia S., Graham, Barney S., McLellan, Jason S., Ward, Andrew B.
Publicado 2016

Mechanism of assembly of an elongation-competent SARS-CoV-2 replication transcription complex

por Klein, Misha, Bera, Subhas C., Anderson, Thomas K., Wang, Bing, Papini, Flavia S., Arnold, Jamie J., Cameron, Craig E., Depken, Martin, Kirchdoerfer, Robert N., Artsimovitch, Irina, Dulin, David
Publicado 2023

Structure of the Reston ebolavirus VP30 C-terminal domain

por Clifton, Matthew C., Kirchdoerfer, Robert N., Atkins, Kateri, Abendroth, Jan, Raymond, Amy, Grice, Rena, Barnes, Steve, Moen, Spencer, Lorimer, Don, Edwards, Thomas E., Myler, Peter J., Saphire, Erica Ollmann
Publicado 2014

The nucleotide addition cycle of the SARS-CoV-2 polymerase

por Bera, Subhas Chandra, Seifert, Mona, Kirchdoerfer, Robert N., van Nies, Pauline, Wubulikasimu, Yibulayin, Quack, Salina, Papini, Flávia S., Arnold, Jamie J., Canard, Bruno, Cameron, Craig E., Depken, Martin, Dulin, David
Publicado 2021

The nucleotide addition cycle of the SARS-CoV-2 polymerase

por Bera, Subhas Chandra, Seifert, Mona, Kirchdoerfer, Robert N., van Nies, Pauline, Wubulikasimu, Yibulayin, Quack, Salina, Papini, Flávia S., Arnold, Jamie J., Canard, Bruno, Cameron, Craig E., Depken, Martin, Dulin, David
Publicado 2021

Interfering with nucleotide excision by the coronavirus 3′-to-5′ exoribonuclease

por Chinthapatla, Rukesh, Sotoudegan, Mohamad, Srivastava, Pankaj, Anderson, Thomas K, Moustafa, Ibrahim M, Passow, Kellan T, Kennelly, Samantha A, Moorthy, Ramkumar, Dulin, David, Feng, Joy Y, Harki, Daniel A, Kirchdoerfer, Robert N, Cameron, Craig E, Arnold, Jamie J
Publicado 2022

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

por Lin, Aaron E., Diehl, William E., Cai, Yingyun, Finch, Courtney L., Akusobi, Chidiebere, Kirchdoerfer, Robert N., Bollinger, Laura, Schaffner, Stephen F., Brown, Elizabeth A., Saphire, Erica Ollmann, Andersen, Kristian G., Kuhn, Jens H., Luban, Jeremy, Sabeti, Pardis C.
Publicado 2020

Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

por Wang, Nianshuang, Rosen, Osnat, Wang, Lingshu, Turner, Hannah L., Stevens, Laura J., Corbett, Kizzmekia S., Bowman, Charles A., Pallesen, Jesper, Shi, Wei, Zhang, Yi, Leung, Kwanyee, Kirchdoerfer, Robert N., Becker, Michelle M., Denison, Mark R., Chappell, James D., Ward, Andrew B., Graham, Barney S., McLellan, Jason S.
Publicado 2019

From structure to sequence: Antibody discovery using cryoEM

por Antanasijevic, Aleksandar, Bowman, Charles A., Kirchdoerfer, Robert N., Cottrell, Christopher A., Ozorowski, Gabriel, Upadhyay, Amit A., Cirelli, Kimberly M., Carnathan, Diane G., Enemuo, Chiamaka A., Sewall, Leigh M., Nogal, Bartek, Zhao, Fangzhu, Groschel, Bettina, Schief, William R., Sok, Devin, Silvestri, Guido, Crotty, Shane, Bosinger, Steven E., Ward, Andrew B.
Publicado 2022