Quadruple and Truncated MEK3 Mutants Identified from Acute Lymphoblastic Leukemia Promote Degradation and Enhance Proliferation

por Ayala-Marin, Yoshira M., Grant, Alice H., Rodriguez, Georgialina, Kirken, Robert A.
Publicado 2021

The SARS‐CoV‐2 origin dilemma: Zoonotic transfer or laboratory leak?

por Ruiz‐Medina, Blanca E., Varela‐Ramirez, Armando, Kirken, Robert A., Robles‐Escajeda, Elisa
Publicado 2021

Inhibition of JAK3 with a novel, selective, and orally active small molecule induces therapeutic response in T-cell malignancies

por Ross, Jeremy A., Spadaro, Michela, Rosado, Damaris C., Cavallo, Federica, Kirken, Robert A., Pericle, Federica
Publicado 2013

The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignancies

por Ross, Jeremy A., Robles-Escajeda, Elisa, Oaxaca, Derrick M., Padilla, Diana L., Kirken, Robert A.
Publicado 2017

STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells

por Nagy, Zsuzsanna S, LeBaron, Matthew J, Ross, Jeremy A, Mitra, Abhisek, Rui, Hallgeir, Kirken, Robert A
Publicado 2009

Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells

por Nagy, Zsuzsanna S., Ross, Jeremy A., Rodriguez, Georgialina, Balint, Balint L., Szeles, Lajos, Nagy, Laszlo, Kirken, Robert A.
Publicado 2013

Correction: Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells

por Nagy, Zsuzsanna S., Ross, Jeremy A., Rodriguez, Georgialina, Balint, Balint L., Szeles, Lajos, Nagy, Laszlo, Kirken, Robert A.
Publicado 2013

Sensitivity of imatinib-resistant T315I BCR-ABL CML to a synergistic combination of ponatinib and forskolin treatment

por Oaxaca, Derrick M., Yang-Reid, Sun Ah, Ross, Jeremy A., Rodriguez, Georgialina, Staniswalis, Joan G., Kirken, Robert A.
Publicado 2016

Optimization of biomarkers-based classification scores as progression-free survival predictors: an intuitive graphical representation

por Manciu, Marian, Hosseini, Sorour, Di Desidero, Teresa, Allegrini, Giacomo, Falcone, Alfredo, Bocci, Guido, Kirken, Robert A, Francia, Giulio
Publicado 2018

Rapid Shift from SARS-CoV-2 Delta to Omicron Sub-Variants within a Dynamic Southern U.S. Borderplex

por Robles-Escajeda, Elisa, Mohl, Jonathon E., Contreras, Lisett, Betancourt, Ana P., Mancera, Bibiana M., Kirken, Robert A., Rodriguez, Georgialina
Publicado 2023

Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies

por Rodriguez Moncivais, Omar J., Chavez, Stephanie A., Estrada Jimenez, Victor H., Sun, Shengjie, Li, Lin, Kirken, Robert A., Rodriguez, Georgialina
Publicado 2023

Searching in Mother Nature for Anti-Cancer Activity: Anti-Proliferative and Pro-Apoptotic Effect Elicited by Green Barley on Leukemia/Lymphoma Cells

por Robles-Escajeda, Elisa, Lerma, Dennise, Nyakeriga, Alice M., Ross, Jeremy A., Kirken, Robert A., Aguilera, Renato J., Varela-Ramirez, Armando
Publicado 2013

Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction

por Estrada, Armando, Rodriguez, Alejandro C., Rodriguez, Georgialina, Grant, Alice H., Ayala-Marin, Yoshira M., Arrieta, Amy J., Kirken, Robert A.
Publicado 2021

Integration of a Personalized Molecular Targeted Therapy into the Multimodal Treatment of Refractory Childhood Embryonal Tumor with Multilayered Rosettes (ETMR)

por Hartman, Lisa L.R., Oaxaca, Derrick M., Carcamo, Benjamin, Wilson, Harry L., Ross, Jeremy A., Robles-Escajeda, Elisa, Kirken, Robert A.
Publicado 2019

JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling

por Grant, Alice H., Rodriguez, Alejandro C., Rodriguez Moncivais, Omar J., Sun, Shengjie, Li, Lin, Mohl, Jonathon E., Leung, Ming-Ying, Kirken, Robert A., Rodriguez, Georgialina
Publicado 2023

Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways

por Ruiz-Medina, Blanca E., Lerma, Dennise, Hwang, Michael, Ross, Jeremy A., Skouta, Rachid, Aguilera, Renato J., Kirken, Robert A., Varela-Ramirez, Armando, Robles-Escajeda, Elisa
Publicado 2019

The Many Faces of JAKs and STATs Within the COVID-19 Storm

por Grant, Alice H., Estrada, Armando, Ayala-Marin, Yoshira M., Alvidrez-Camacho, America Y., Rodriguez, Georgialina, Robles-Escajeda, Elisa, Cadena-Medina, Denisse A., Rodriguez, Alejandro C., Kirken, Robert A.
Publicado 2021

Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth

por Parra, Karla, Valenzuela, Paloma, Lerma, Natzidielly, Gallegos, Alejandra, Reza, Luis C, Rodriguez, Georgialina, Emmenegger, Urban, Di Desidero, Teresa, Bocci, Guido, Felder, Mitchell S, Manciu, Marian, Kirken, Robert A, Francia, Giulio
Publicado 2017

Identification of a Unique Cytotoxic Thieno[2,3-c]Pyrazole Derivative with Potent and Selective Anticancer Effects In Vitro

por Hess, Jessica D., Macias, Luca H., Gutierrez, Denisse A., Moran-Santibanez, Karla, Contreras, Lisett, Medina, Stephanie, Villanueva, Paulina J., Kirken, Robert A., Varela-Ramirez, Armando, Penichet, Manuel L., Aguilera, Renato J.
Publicado 2022

Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways

por Gutierrez, Denisse A., Contreras, Lisett, Villanueva, Paulina J., Borrego, Edgar A., Morán-Santibañez, Karla, Hess, Jessica D., DeJesus, Rebecca, Larragoity, Manuel, Betancourt, Ana P., Mohl, Jonathon E., Robles-Escajeda, Elisa, Begum, Khodeza, Roy, Sourav, Kirken, Robert A., Varela-Ramirez, Armando, Aguilera, Renato J.
Publicado 2022