History of the Selective Autophagy Research: How Did It Begin and Where Does It Stand Today?

por Kirkin, Vladimir
Publicado 2020

Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond

por Wesch, Nicole, Kirkin, Vladimir, Rogov, Vladimir V.
Publicado 2020

Targeting autophagy in disease: established and new strategies

por Kocak, Muhammed, Ezazi Erdi, Saba, Jorba, Guillem, Maestro, Inés, Farrés, Judith, Kirkin, Vladimir, Martinez, Ana, Pless, Ole
Publicado 2021

Therapeutic Dose Response of Acoustic Cluster Therapy in Combination With Irinotecan for the Treatment of Human Colon Cancer in Mice

por Bush, Nigel, Healey, Andrew, Shah, Anant, Box, Gary, Kirkin, Vladimir, Kotopoulis, Spiros, Kvåle, Svein, Sontum, Per Christian, Bamber, Jeffrey
Publicado 2019

Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma

por Sriskandarajah, Priya, De Haven Brandon, Alexis, MacLeod, Kenneth, Carragher, Neil O., Kirkin, Vladimir, Kaiser, Martin, Whittaker, Steven R.
Publicado 2020

Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice

por De Haven Brandon, Alexis, Box, Gary, Hallsworth, Albert, Court, William, Matthews, Nicoll, Herodek, Balint, Arteagabeitia, Aitor Bermejo, Valenti, Melanie, Kirkin, Vladimir
Publicado 2020

Theranostic Attributes of Acoustic Cluster Therapy and Its Use for Enhancing the Effectiveness of Liposomal Doxorubicin Treatment of Human Triple Negative Breast Cancer in Mice

por Bush, Nigel, Healey, Andrew, Shah, Anant, Box, Gary, Kirkin, Vladimir, Eccles, Sue, Sontum, Per Christian, Kotopoulis, Spiros, Kvåle, Svein, van Wamel, Annemieke, Davies, Catharina de Lange, Bamber, Jeffrey
Publicado 2020

Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy

por Kraft, Claudine, Boya, Patricia, Codogno, Patrice, Elazar, Zvulun, Eskelinen, Eeva-Liisa, Farrés, Judith, Kirkin, Vladimir, Jungbluth, Heinz, Martinez, Ana, Pless, Ole, Primard, Charlotte, Proikas-Cezanne, Tassula, Simonsen, Anne, Reggiori, Fulvio
Publicado 2018

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

por Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Publicado 2019

Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer

por Wagner, Steve, Vlachogiannis, Georgios, De Haven Brandon, Alexis, Valenti, Melanie, Box, Gary, Jenkins, Liam, Mancusi, Caterina, Self, Annette, Manodoro, Floriana, Assiotis, Ioannis, Robinson, Penny, Chauhan, Ritika, Rust, Alistair G., Matthews, Nik, Eason, Kate, Khan, Khurum, Starling, Naureen, Cunningham, David, Sadanandam, Anguraj, Isacke, Clare M., Kirkin, Vladimir, Valeri, Nicola, Whittaker, Steven R.
Publicado 2018

Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer

por Wagner, Steve, Vlachogiannis, Georgios, De Haven Brandon, Alexis, Valenti, Melanie, Box, Gary, Jenkins, Liam, Mancusi, Caterina, Self, Annette, Manodoro, Floriana, Assiotis, Ioannis, Robinson, Penny, Chauhan, Ritika, Rust, Alistair G., Matthews, Nik, Eason, Kate, Khan, Khurum, Starling, Naureen, Cunningham, David, Sadanandam, Anguraj, Isacke, Clare M., Kirkin, Vladimir, Valeri, Nicola, Whittaker, Steven R.
Publicado 2019

FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas

por Milton, Christopher I., Selfe, Joanna, Aladowicz, Ewa, Man, Stella Y. K., Bernauer, Carolina, Missiaglia, Edoardo, Walters, Zoë S., Gatz, Susanne A., Kelsey, Anna, Generali, Melanie, Box, Gary, Valenti, Melanie, de Haven‐Brandon, Alexis, Galiwango, David, Hayes, Angela, Clarke, Matthew, Izquierdo, Elisa, Gonzalez De Castro, David, Raynaud, Florence I., Kirkin, Vladimir, Shipley, Janet M.
Publicado 2021

Modulation of Biliary Cancer Chemo‐Resistance Through MicroRNA‐Mediated Rewiring of the Expansion of CD133+ Cells

por Carotenuto, Pietro, Hedayat, Somaieh, Fassan, Matteo, Cardinale, Vincenzo, Lampis, Andrea, Guzzardo, Vincenza, Vicentini, Caterina, Scarpa, Aldo, Cascione, Luciano, Costantini, Daniele, Carpino, Guido, Alvaro, Domenico, Ghidini, Michele, Trevisani, Francesco, Te Poele, Robert, Salati, Massimiliano, Ventura, Sofia, Vlachogiannis, Georgios, Hahne, Jens C., Boulter, Luke, Forbes, Stuart J., Guest, Rachel V., Cillo, Umberto, Said‐Huntingford, Ian, Begum, Ruwaida, Smyth, Elizabeth, Michalarea, Vasiliki, Cunningham, David, Rimassa, Lorenza, Santoro, Armando, Roncalli, Massimo, Kirkin, Vladimir, Clarke, Paul, Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publicado 2020

Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones

por Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
Publicado 2023

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

por Bellenie, Benjamin R., Cheung, Kwai-Ming J., Varela, Ana, Pierrat, Olivier A., Collie, Gavin W., Box, Gary M., Bright, Michael D., Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J., Shetty, Kartika N., Carter, Michael, Davis, Owen A., Henley, Alan T., Innocenti, Paolo, Johnson, Louise D., Liu, Manjuan, de Klerk, Selby, Le Bihan, Yann-Vaï, Lloyd, Matthew G., McAndrew, P. Craig, Shehu, Erald, Talbot, Rachel, Woodward, Hannah L., Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Hoelder, Swen
Publicado 2020

Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage

por Carotenuto, Pietro, Amato, Francesco, Lampis, Andrea, Rae, Colin, Hedayat, Somaieh, Previdi, Maria C., Zito, Domenico, Raj, Maya, Guzzardo, Vincenza, Sclafani, Francesco, Lanese, Andrea, Parisi, Claudia, Vicentini, Caterina, Said-Huntingford, Ian, Hahne, Jens C., Hallsworth, Albert, Kirkin, Vladimir, Young, Kate, Begum, Ruwaida, Wotherspoon, Andrew, Kouvelakis, Kyriakos, Azevedo, Sergio Xavier, Michalarea, Vasiliki, Upstill-Goddard, Rosie, Rao, Sheela, Watkins, David, Starling, Naureen, Sadanandam, Anguraj, Chang, David K., Biankin, Andrew V., Jamieson, Nigel B., Scarpa, Aldo, Cunningham, David, Chau, Ian, Workman, Paul, Fassan, Matteo, Valeri, Nicola, Braconi, Chiara
Publicado 2021

Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo

por Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
Publicado 2022