Pathways and disease-causing alterations in visual chromophore production for vertebrate vision

por Kiser, Philip D., Palczewski, Krzysztof
Publicado 2020

Chemistry of the Retinoid (Visual) Cycle

por Kiser, Philip D., Golczak, Marcin, Palczewski, Krzysztof
Publicado 2013

LRAT-specific domain facilitates Vitamin A metabolism by domain swapping in HRASLS

por Golczak, Marcin, Sears, Avery E., Kiser, Philip D., Palczewski, Krzysztof
Publicado 2014

Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration

por Lobo, Glenn P., Au, Adrian, Kiser, Philip D., Hagstrom, Stephanie A.
Publicado 2016

Function of mammalian M-cones depends on the level of CRALBP in Müller cells

por Kolesnikov, Alexander V., Kiser, Philip D., Palczewski, Krzysztof, Kefalov, Vladimir J.
Publicado 2020

Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes

por Hong, John D., Salom, David, Kochman, Michał Andrzej, Kubas, Adam, Kiser, Philip D., Palczewski, Krzysztof
Publicado 2022

Preparation and characterization of metal-substituted carotenoid cleavage oxygenases

por Sui, Xuewu, Farquhar, Erik R., Hill, Hannah E., von Lintig, Johannes, Shi, Wuxian, Kiser, Philip D.
Publicado 2018

Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody

por Sears, Avery E., Albiez, Stefan, Gulati, Sahil, Wang, Benlian, Kiser, Philip, Kovacik, Lubomir, Engel, Andreas, Stahlberg, Henning, Palczewski, Krzysztof
Publicado 2020

Catalytic mechanism of a retinoid isomerase essential for vertebrate vision

por Kiser, Philip D., Zhang, Jianye, Badiee, Mohsen, Li, Qingjiang, Shi, Wuxian, Sui, Xuewu, Golczak, Marcin, Tochtrop, Gregory P., Palczewski, Krzysztof
Publicado 2015

Structure of 3-mercaptopropionic acid dioxygenase with a substrate analog reveals bidentate substrate binding at the iron center

por York, Nicholas J., Lockart, Molly M., Sardar, Sinjinee, Khadka, Nimesh, Shi, Wuxian, Stenkamp, Ronald E., Zhang, Jianye, Kiser, Philip D., Pierce, Brad S.
Publicado 2021

Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain

por Wu, Arum, Salom, David, Hong, John D., Tworak, Aleksander, Watanabe, Kohei, Pardon, Els, Steyaert, Jan, Kandori, Hideki, Katayama, Kota, Kiser, Philip D., Palczewski, Krzysztof
Publicado 2023

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

por Gulati, Sahil, Jin, Hui, Masuho, Ikuo, Orban, Tivadar, Cai, Yuan, Pardon, Els, Martemyanov, Kirill A., Kiser, Philip D., Stewart, Phoebe L., Ford, Christopher P., Steyaert, Jan, Palczewski, Krzysztof
Publicado 2018

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function

por Kiser, Philip D., Zhang, Jianye, Sharma, Aditya, Angueyra, Juan M., Kolesnikov, Alexander V., Badiee, Mohsen, Tochtrop, Gregory P., Kinoshita, Junzo, Peachey, Neal S., Li, Wei, Kefalov, Vladimir J., Palczewski, Krzysztof
Publicado 2018

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

por Kiser, Philip D., Kolesnikov, Alexander V., Kiser, Jianying Z., Dong, Zhiqian, Chaurasia, Bhagirath, Wang, Liping, Summers, Scott A., Hoang, Thanh, Blackshaw, Seth, Peachey, Neal S., Kefalov, Vladimir J., Palczewski, Krzysztof
Publicado 2019

An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

por Choi, Elliot H., Suh, Susie, Einstein, David E., Leinonen, Henri, Dong, Zhiqian, Rao, Sriganesh Ramachandra, Fliesler, Steven J., Blackshaw, Seth, Yu, Minzhong, Peachey, Neal S., Palczewski, Krzysztof, Kiser, Philip D.
Publicado 2021

Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells

por Montano, Monica M., Yeh, I-Ju, Chen, Yinghua, Hernandez, Chris, Kiselar, Janna G., de la Fuente, Maria, Lawes, Adriane M., Nieman, Marvin T., Kiser, Philip D., Jacobberger, James, Exner, Agata A., Lawes, Matthew C.
Publicado 2019

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

por Tworak, Aleksander, Kolesnikov, Alexander V., Hong, John D., Choi, Elliot H., Luu, Jennings C., Palczewska, Grazyna, Dong, Zhiqian, Lewandowski, Dominik, Brooks, Matthew J., Campello, Laura, Swaroop, Anand, Kiser, Philip D., Kefalov, Vladimir J., Palczewski, Krzysztof
Publicado 2023

Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition

por Sander, Christopher L., Sears, Avery E., Pinto, Antonio F.M., Choi, Elliot H., Kahremany, Shirin, Gao, Fangyuan, Salom, David, Jin, Hui, Pardon, Els, Suh, Susie, Dong, Zhiqian, Steyaert, Jan, Saghatelian, Alan, Skowronska-Krawczyk, Dorota, Kiser, Philip D., Palczewski, Krzysztof
Publicado 2021

Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

por C. Luu, Jennings, Saadane, Aicha, Leinonen, Henri, H. Choi, Elliot, Gao, Fangyuan, Lewandowski, Dominik, Halabi, Maximilian, L. Sander, Christopher, Wu, Arum, Wang, Jacob M., Singh, Rupesh, Gao, Songqi, Lessieur, Emma M., Dong, Zhiqian, Palczewska, Grazyna, Mullins, Robert F., Peachey, Neal S., Kiser, Philip D., Tabaka, Marcin, Kern, Timothy S., Palczewski, Krzysztof
Publicado 2023