Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

por Kistemaker, Loes E. M., Bos, I. Sophie T., Menzen, Mark H., Maarsingh, Harm, Meurs, Herman, Gosens, Reinoud
Publicado 2016

Function-specific IL-17A and dexamethasone interactions in primary human airway epithelial cells

por Rahmawati, Siti Farah, Vos, Rémon, Bos, I. Sophie T., Kerstjens, Huib A. M., Kistemaker, Loes E. M., Gosens, Reinoud
Publicado 2022

Cigarette smoke up‐regulates PDE3 and PDE4 to decrease cAMP in airway cells

por Zuo, Haoxiao, Han, Bing, Poppinga, Wilfred J, Ringnalda, Lennard, Kistemaker, Loes E M, Halayko, Andrew J, Gosens, Reinoud, Nikolaev, Viacheslav O, Schmidt, Martina
Publicado 2018

Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors

por Wu, Xinhui, van Dijk, Eline M., Ng-Blichfeldt, John-Poul, Bos, I. Sophie T., Ciminieri, Chiara, Königshoff, Melanie, Kistemaker, Loes E.M., Gosens, Reinoud
Publicado 2019

Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice

por Hiorns, Jonathan E., Bidan, Cécile M., Jensen, Oliver E., Gosens, Reinoud, Kistemaker, Loes E. M., Fredberg, Jeffrey J., Butler, Jim P., Krishnan, Ramaswamy, Brook, Bindi S.
Publicado 2016

Corrigendum: Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice

por Hiorns, Jonathan E., Bidan, Cécile M., Jensen, Oliver E., Gosens, Reinoud, Kistemaker, Loes E. M., Fredberg, Jeffrey J., Butler, Jim P., Krishnan, Ramaswamy, Brook, Bindi S.
Publicado 2017

Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

por Wu, Xinhui, Verschut, Vicky, Woest, Manon E., Ng-Blichfeldt, John-Poul, Matias, Ana, Villetti, Gino, Accetta, Alessandro, Facchinetti, Fabrizio, Gosens, Reinoud, Kistemaker, Loes E. M.
Publicado 2021

The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs

por van den Berg, Mariska P. M., Nijboer-Brinksma, Susan, Bos, I. Sophie T., van den Berge, Maarten, Lamb, David, van Faassen, Martijn, Kema, Ido P., Gosens, Reinoud, Kistemaker, Loes E. M.
Publicado 2021

HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional a...

por Leus, Niek G.J., van der Wouden, Petra E., van den Bosch, Thea, Hooghiemstra, Wouter T.R., Ourailidou, Maria E., Kistemaker, Loes E.M., Bischoff, Rainer, Gosens, Reinoud, Haisma, Hidde J., Dekker, Frank J.
Publicado 2016

A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration

por Wu, Xinhui, Bos, I. Sophie T., Conlon, Thomas M., Ansari, Meshal, Verschut, Vicky, van der Koog, Luke, Verkleij, Lars A., D’Ambrosi, Angela, Matveyenko, Aleksey, Schiller, Herbert B., Königshoff, Melanie, Schmidt, Martina, Kistemaker, Loes E. M., Yildirim, Ali Önder, Gosens, Reinoud
Publicado 2022

HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice

por Leus, Niek G. J., van den Bosch, Thea, van der Wouden, Petra E., Krist, Kim, Ourailidou, Maria E., Eleftheriadis, Nikolaos, Kistemaker, Loes E. M., Bos, Sophie, Gjaltema, Rutger A. F., Mekonnen, Solomon A., Bischoff, Rainer, Gosens, Reinoud, Haisma, Hidde J., Dekker, Frank J.
Publicado 2017

Cholinergic neuroplasticity in asthma driven by TrkB signaling

por Dragunas, Guilherme, Woest, Manon E., Nijboer, Susan, Bos, Sophie T., van Asselt, Janet, de Groot, Anne P., Vohlídalová, Eva, Vermeulen, Corneel J., Ditz, Benedikt, Vonk, Judith M., Koppelman, Gerard H., van den Berge, Maarten, ten Hacken, Nick H. T., Timens, Wim, Munhoz, Carolina D., Prakash, Y. S., Gosens, Reinoud, Kistemaker, Loes E. M.
Publicado 2020