Inhibitory Effect of Zinc on Colorectal Cancer by Granzyme B Transcriptional Regulation in Cytotoxic T Cells

por Nakagawa, Naoya, Fujisawa, Yutaka, Xiang, Huihui, Kitamura, Hidemitsu, Nishida, Keigo
Publicado 2023

IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway

por Sumida, Kentaro, Ohno, Yosuke, Ohtake, Junya, Kaneumi, Shun, Kishikawa, Takuto, Takahashi, Norihiko, Taketomi, Akinobu, Kitamura, Hidemitsu
Publicado 2015

Interleukin‐6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapy

por Kitamura, Hidemitsu, Ohno, Yosuke, Toyoshima, Yujiro, Ohtake, Junya, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu
Publicado 2017

IFN‐γ–STAT1‐mediated NK2R expression is involved in the induction of antitumor effector CD8 (+) T cells in vivo

por Shen, Weidong, Wang, Xiangdong, Xiang, Huihui, Shichi, Shunsuke, Nakamoto, Hiroki, Kimura, Saori, Sugiyama, Ko, Taketomi, Akinobu, Kitamura, Hidemitsu
Publicado 2023

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8(+) T cells

por Tajima, Masaki, Wakita, Daiko, Noguchi, Daisuke, Chamoto, Kenji, Yue, Zhang, Fugo, Kazunori, Ishigame, Harumichi, Iwakura, Yoichiro, Kitamura, Hidemitsu, Nishimura, Takashi
Publicado 2008

Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells

por Wang, Xiangdong, Xiang, Huihui, Toyoshima, Yujiro, Shen, Weidong, Shichi, Shunsuke, Nakamoto, Hiroki, Kimura, Saori, Sugiyama, Ko, Homma, Shigenori, Miyagi, Yohei, Taketomi, Akinobu, Kitamura, Hidemitsu
Publicado 2023

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Recep...

por Kitamura, Hidemitsu, Iwakabe, Kenji, Yahata, Takashi, Nishimura, Shin-ichiro, Ohta, Akio, Ohmi, Yasushi, Sato, Marimo, Takeda, Kazuyoshi, Okumura, Ko, Van Kaer, Luc, Kawano, Tetsu, Taniguchi, Masaru, Nishimura, Takashi
Publicado 1999

IFN‐α/β‐mediated NK2R expression is related to the malignancy of colon cancer cells

por Xiang, Huihui, Toyoshima, Yujiro, Shen, Weidong, Wang, Xiangdong, Okada, Naoki, Kii, Shuhei, Sugiyama, Ko, Nagato, Toshihiro, Kobayashi, Hiroya, Ikeo, Kazuho, Hashimoto, Shinichi, Tanino, Mishie, Taketomi, Akinobu, Kitamura, Hidemitsu
Publicado 2022

Lack of interleukin‐6 in the tumor microenvironment augments type‐1 immunity and increases the efficacy of cancer immunotherapy

por Ohno, Yosuke, Toyoshima, Yujiro, Yurino, Hideaki, Monma, Norikazu, Xiang, Huihui, Sumida, Kentaro, Kaneumi, Shun, Terada, Satoshi, Hashimoto, Shinichi, Ikeo, Kazuho, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu, Kitamura, Hidemitsu
Publicado 2017

CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes

por Kosaka, Akemi, Ishibashi, Kei, Nagato, Toshihiro, Kitamura, Hidemitsu, Fujiwara, Yukio, Yasuda, Syunsuke, Nagata, Marino, Harabuchi, Shohei, Hayashi, Ryusuke, Yajima, Yuki, Ohara, Kenzo, Kumai, Takumi, Aoki, Naoko, Komohara, Yoshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Kitada, Masahiro, Kobayashi, Hiroya, Ohkuri, Takayuki
Publicado 2021

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR

por Kamimura, Daisuke, Katsunuma, Kokichi, Arima, Yasunobu, Atsumi, Toru, Jiang, Jing-jing, Bando, Hidenori, Meng, Jie, Sabharwal, Lavannya, Stofkova, Andrea, Nishikawa, Naoki, Suzuki, Hironao, Ogura, Hideki, Ueda, Naoko, Tsuruoka, Mineko, Harada, Masaya, Kobayashi, Junya, Hasegawa, Takanori, Yoshida, Hisahiro, Koseki, Haruhiko, Miura, Ikuo, Wakana, Shigeharu, Nishida, Keigo, Kitamura, Hidemitsu, Fukada, Toshiyuki, Hirano, Toshio, Murakami, Masaaki
Publicado 2015