AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

por Kiyota, Tomomi, Ingraham, Kaitlin L., Swan, Russell J., Jacobsen, Michael T., Andrews, Scott J., Ikezu, Tsuneya
Publicado 2011

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

por Embury, Christine M, Dyavarshetty, Bhagyalaxmi, Lu, Yaman, Wiederin, Jayme L, Ciborowski, Pawel, Gendelman, Howard E, Kiyota, Tomomi
Publicado 2016

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

por Kiyota, Tomomi, Yamamoto, Masaru, Xiong, Huangui, Lambert, Mary P., Klein, William L., Gendelman, Howard E., Ransohoff, Richard M., Ikezu, Tsuneya
Publicado 2009

AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease

por Kiyota, Tomomi, Zhang, Gang, Morrison, Christine M, Bosch, Megan E, Weir, Robert A, Lu, Yaman, Dong, Weiguo, Gendelman, Howard E
Publicado 2015

The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation

por Dong, Weiguo, Embury, Christine M., Lu, Yaman, Whitmire, Sarah M., Dyavarshetty, Bhagyalaxmi, Gelbard, Harris A., Gendelman, Howard E., Kiyota, Tomomi
Publicado 2016

URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease

por Kiyota, Tomomi, Machhi, Jatin, Lu, Yaman, Dyavarshetty, Bhagyalaxmi, Nemati, Maryam, Zhang, Gang, Mosley, R. Lee, Gelbard, Harris A., Gendelman, Howard E.
Publicado 2018

CD4+ effector T cells accelerate Alzheimer’s disease in mice

por Machhi, Jatin, Yeapuri, Pravin, Lu, Yaman, Foster, Emma, Chikhale, Rupesh, Herskovitz, Jonathan, Namminga, Krista L., Olson, Katherine E., Abdelmoaty, Mai Mohamed, Gao, Ju, Quadros, Rolen M., Kiyota, Tomomi, Jingjing, Liang, Kevadiya, Bhavesh D., Wang, Xinglong, Liu, Yutong, Poluektova, Larisa Y., Gurumurthy, Channabasavaiah B., Mosley, R. Lee, Gendelman, Howard E.
Publicado 2021