Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism

por Harwood, Seandean Lykke, Lyngsø, Jeppe, Zarantonello, Alessandra, Kjøge, Katarzyna, Nielsen, Peter Kresten, Andersen, Gregers Rom, Pedersen, Jan Skov, Enghild, Jan J.
Publicado 2021

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family

por Nielsen, Nadia Sukusu, Zarantonello, Alessandra, Harwood, Seandean Lykke, Jensen, Kathrine Tejlgård, Kjøge, Katarzyna, Thøgersen, Ida B., Schauser, Leif, Karlsen, Jesper Lykkegaard, Andersen, Gregers R., Enghild, Jan J.
Publicado 2022