Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

por De Bastiani, Marco Antônio, Klamt, Fábio
Publicado 2019

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

por De Bastiani, Marco A., Pfaffenseller, Bianca, Klamt, Fabio
Publicado 2018

EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

por Pfaffenseller, Bianca, Kapczinski, Flavio, Gallitano, Amelia L., Klamt, Fábio
Publicado 2018

Taurine chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats submitted to sepsis

por Dall'Igna, Dhébora Mozena, da Luz, Jaqueline Maffezzolli, Vuolo, Francieli, Klamt, Fábio, Pizzol, Felipe Dal
Publicado 2013

Antioxidant defense capacity of ovarian tissue after vitrification in a metal closed system

por Massignam, Eloísa T., Ferreira, Maitê, Sanguinet, Eduardo, Dupont, Ágata, Klamt, Fábio, Frantz, Nilo, Bos-Mikich, Adriana
Publicado 2018

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

por Pereira, Mery Stefani Leivas, Klamt, Fábio, Thomé, Chairini Cássia, Worm, Paulo Valdeci, de Oliveira, Diogo Losch
Publicado 2017

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignan...

por Bracalente, Candelaria, Ibañez, Irene L., Berenstein, Ariel, Notcovich, Cintia, Cerda, María B., Klamt, Fabio, Chernomoretz, Ariel, Durán, Hebe
Publicado 2016

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

por Bracalente, Candelaria, Salguero, Noelia, Notcovich, Cintia, Müller, Carolina B., da Motta, Leonardo L., Klamt, Fabio, Ibañez, Irene L., Durán, Hebe
Publicado 2016

Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients

por Bracalente, Candelaria, Rinflerch, Adriana R., Ibañez, Irene L., García, Francisco M., Volonteri, Victoria, Galimberti, Gastón N., Klamt, Fabio, Durán, Hebe
Publicado 2018

Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancer

por Müller, Carolina Beatriz, De Bastiani, Marco Antônio, Becker, Matheus, França, Fernanda Stapenhorst, Branco, Mariane Araujo, Castro, Mauro Antônio Alves, Klamt, Fábio
Publicado 2015

High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer’s Disease

por Kocinaj, Altin, Chaudhury, Tabassum, Uddin, Mohammed S., Junaid, Rashad R., Ramsden, David B., Hondhamuni, Geshanthi, Klamt, Fábio, Parsons, Linda, Parsons, Richard B.
Publicado 2021

A comparative study of COVID-19 transcriptional signatures between clinical samples and preclinical cell models in the search for disease master regulators and drug repositioning c...

por Chapola, Henrique, de Bastiani, Marco Antônio, Duarte, Marcelo Mendes, Freitas, Matheus Becker, Schuster, Jussara Severo, de Vargas, Daiani Machado, Klamt, Fábio
Publicado 2023

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

por Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Figueiró, Fabrício, Andrade, Cristiano Feijó, Klamt, Fábio
Publicado 2020

Reduced Neurite Density in Neuronal Cell Cultures Exposed to Serum of Patients with Bipolar Disorder

por Wollenhaupt-Aguiar, Bianca, Pfaffenseller, Bianca, Chagas, Vinicius de Saraiva, Castro, Mauro A A, Passos, Ives Cavalcante, Kauer-Sant’Anna, Márcia, Kapczinski, Flavio, Klamt, Fábio
Publicado 2016

Increased Oxidative Damage in Carriers of the Germline TP53 p.R337H Mutation

por Macedo, Gabriel S., Lisbôa da Motta, Leonardo, Giacomazzi, Juliana, Netto, Cristina B. O., Manfredini, Vanusa, S.Vanzin, Camila, Vargas, Carmen Regla, Hainaut, Pierre, Klamt, Fábio, Ashton-Prolla, Patricia
Publicado 2012

Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease

por Becker, Matheus, De Bastiani, Marco A., Parisi, Mariana M., Guma, Fátima T. C. R., Markoski, Melissa M., Castro, Mauro A. A., Kaplan, Mark H., Barbé-Tuana, Florencia M., Klamt, Fábio
Publicado 2015

Caveolin‐1 influences mitochondrial plasticity and function in hepatic stellate cell activation

por Ilha, Mariana, Meira Martins, Leo A., da Silveira Moraes, Ketlen, Dias, Camila K., Thomé, Marcos P., Petry, Fernanda, Rohden, Francieli, Borojevic, Radovan, Trindade, Vera M. T., Klamt, Fábio, Barbé‐Tuana, Florência, Lenz, Guido, Guma, Fátima C. R.
Publicado 2022

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

por Ferrari, Pamela, Parisi, Mariana Migliorini, Colombo, Rafael, Becker, Matheus, Fries, Gabriel, Ascoli, Bruna Maria, Géa, Luiza Paul, Kauer-Sant’anna, Márcia, Kapczinski, Flávio, Klamt, Fábio, Guma, Fátima T.C.R., Rosa, Adriane Ribeiro, Barbé-Tuana, Florencia M.
Publicado 2018

Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineage

por da Silva, Mariana Soares, Gularte, Juliana Schons, Filippi, Micheli, Demoliner, Meriane, Girardi, Viviane, Mosena, Ana Cristina Sbaraini, Pereira, Vyctoria Malayhka de Abreu Góes, Hansen, Alana Witt, Weber, Matheus Nunes, de Almeida, Paula Rodrigues, Fleck, Juliane Deise, Bó, Andrea Gurgel Batista Leite Dal, Jones, Marcus Herbert, Friedrich, Frederico, Filho, Luiz Amorim, Klamt, Fábio, Spilki, Fernando Rosado
Publicado 2022