Glycosylation Alterations in Multiple Sclerosis Show Increased Proinflammatory Potential

por Cvetko, Ana, Kifer, Domagoj, Gornik, Olga, Klarić, Lucija, Visser, Elizabeth, Lauc, Gordan, Wilson, James F., Štambuk, Tamara
Publicado 2020

Integrating omics datasets with the OmicsPLS package

por Bouhaddani, Said el, Uh, Hae-Won, Jongbloed, Geurt, Hayward, Caroline, Klarić, Lucija, Kiełbasa, Szymon M., Houwing-Duistermaat, Jeanine
Publicado 2018

Serum metabolomic profiles associated with subclinical and clinical cardiovascular phenotypes in people with type 2 diabetes

por Huang, Zhe, Klaric, Lucija, Krasauskaite, Justina, McLachlan, Stela, Strachan, Mark W. J., Wilson, James F., Price, Jackie F.
Publicado 2022

Biological age estimation using circulating blood biomarkers

por Bortz, Jordan, Guariglia, Andrea, Klaric, Lucija, Tang, David, Ward, Peter, Geer, Michael, Chadeau-Hyam, Marc, Vuckovic, Dragana, Joshi, Peter K.
Publicado 2023

Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 d...

por Rudman, Najda, Kaur, Simranjeet, Simunović, Vesna, Kifer, Domagoj, Šoić, Dinko, Keser, Toma, Štambuk, Tamara, Klarić, Lucija, Pociot, Flemming, Morahan, Grant, Gornik, Olga
Publicado 2023

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

por Macdonald-Dunlop, Erin, Taba, Nele, Klarić, Lucija, Frkatović, Azra, Walker, Rosie, Hayward, Caroline, Esko, Tõnu, Haley, Chris, Fischer, Krista, Wilson, James F., Joshi, Peter K.
Publicado 2022

Gene-based whole genome sequencing meta-analysis of 250 circulating proteins in three isolated European populations

por Gilly, Arthur, Klaric, Lucija, Park, Young-Chan, Png, Grace, Barysenka, Andrei, Marsh, Joseph A., Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Wilson, James F., Zeggini, Eleftheria
Publicado 2022

Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies

por Shadrina, Alexandra S., Shashkova, Tatiana I., Torgasheva, Anna A., Sharapov, Sodbo Z., Klarić, Lucija, Pakhomov, Eugene D., Alexeev, Dmitry G., Wilson, James F., Tsepilov, Yakov A., Joshi, Peter K., Aulchenko, Yurii S.
Publicado 2020

Clinical case study meets population cohort: identification of a BRCA1 pathogenic founder variant in Orcadians

por Kerr, Shona M., Cowan, Emma, Klaric, Lucija, Bell, Christine, O’Sullivan, Dawn, Buchanan, David, Grzymski, Joseph J., van Hout, Cristopher V., Tzoneva, Gannie, Shuldiner, Alan R., Wilson, James F., Miedzybrodzka, Zosia
Publicado 2023

Genetic regulation of post-translational modification of two distinct proteins

por Landini, Arianna, Trbojević-Akmačić, Irena, Navarro, Pau, Tsepilov, Yakov A., Sharapov, Sodbo Z., Vučković, Frano, Polašek, Ozren, Hayward, Caroline, Petrović, Tea, Vilaj, Marija, Aulchenko, Yurii S., Lauc, Gordan, Wilson, James F., Klarić, Lucija
Publicado 2022

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

por Shen, Xia, Klarić, Lucija, Sharapov, Sodbo, Mangino, Massimo, Ning, Zheng, Wu, Di, Trbojević-Akmačić, Irena, Pučić-Baković, Maja, Rudan, Igor, Polašek, Ozren, Hayward, Caroline, Spector, Timothy D., Wilson, James F., Lauc, Gordan, Aulchenko, Yurii S.
Publicado 2017

Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

por Kentistou, Katherine A., Luan, Jian’an, Wittemans, Laura B. L., Hambly, Catherine, Klaric, Lucija, Kutalik, Zoltán, Speakman, John R., Wareham, Nicholas J., Kendall, Timothy J., Langenberg, Claudia, Wilson, James F., Joshi, Peter K., Morton, Nicholas M.
Publicado 2023

Comparative analysis of transferrin and IgG N-glycosylation in two human populations

por Trbojević-Akmačić, Irena, Vučković, Frano, Pribić, Tea, Vilaj, Marija, Černigoj, Urh, Vidič, Jana, Šimunović, Jelena, Kępka, Agnieszka, Kolčić, Ivana, Klarić, Lucija, Novokmet, Mislav, Pučić-Baković, Maja, Rapp, Erdmann, Štrancar, Aleš, Polašek, Ozren, Wilson, James F., Lauc, Gordan
Publicado 2023

An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort

por Kerr, Shona M., Klaric, Lucija, Halachev, Mihail, Hayward, Caroline, Boutin, Thibaud S., Meynert, Alison M., Semple, Colin A., Tuiskula, Annukka M., Swan, Heikki, Santoyo-Lopez, Javier, Vitart, Veronique, Haley, Chris, Dean, John, Miedzybrodzka, Zosia, Aitman, Timothy J., Wilson, James F.
Publicado 2019

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

por Halachev, Mihail, Meynert, Alison, Taylor, Martin S., Vitart, Veronique, Kerr, Shona M., Klaric, Lucija, Aitman, Timothy J., Haley, Chris S., Prendergast, James G., Pugh, Carys, Hume, David A., Harris, Sarah E., Liewald, David C., Deary, Ian J., Semple, Colin A., Wilson, James F.
Publicado 2019

Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing

por Png, Grace, Gerlini, Raffaele, Hatzikotoulas, Konstantinos, Barysenka, Andrei, Rayner, N William, Klarić, Lucija, Rathkolb, Birgit, Aguilar-Pimentel, Juan A, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Pietrzik, Claus, Wilson, James F, de Angelis, Martin Hrabe, Becker-Pauly, Christoph, Gilly, Arthur, Zeggini, Eleftheria
Publicado 2022

The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study

por Wang, Youxin, Klarić, Lucija, Yu, Xinwei, Thaqi, Kujtim, Dong, Jing, Novokmet, Mislav, Wilson, Jim, Polasek, Ozren, Liu, Youqin, Krištić, Jasminka, Ge, Siqi, Pučić-Baković, Maja, Wu, Lijuan, Zhou, Yong, Ugrina, Ivo, Song, Manshu, Zhang, Jie, Guo, Xiuhua, Zeng, Qiang, Rudan, Igor, Campbell, Harry, Aulchenko, Yurii, Lauc, Gordan, Wang, Wei
Publicado 2016

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

por Wahl, Annika, van den Akker, Erik, Klaric, Lucija, Štambuk, Jerko, Benedetti, Elisa, Plomp, Rosina, Razdorov, Genadij, Trbojević-Akmačić, Irena, Deelen, Joris, van Heemst, Diana, Slagboom, P. Eline, Vučković, Frano, Grallert, Harald, Krumsiek, Jan, Strauch, Konstantin, Peters, Annette, Meitinger, Thomas, Hayward, Caroline, Wuhrer, Manfred, Beekman, Marian, Lauc, Gordan, Gieger, Christian
Publicado 2018

Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research

por Huffman, Jennifer E., Pučić-Baković, Maja, Klarić, Lucija, Hennig, René, Selman, Maurice H. J., Vučković, Frano, Novokmet, Mislav, Krištić, Jasminka, Borowiak, Matthias, Muth, Thilo, Polašek, Ozren, Razdorov, Genadij, Gornik, Olga, Plomp, Rosina, Theodoratou, Evropi, Wright, Alan F., Rudan, Igor, Hayward, Caroline, Campbell, Harry, Deelder, André M., Reichl, Udo, Aulchenko, Yurii S., Rapp, Erdmann, Wuhrer, Manfred, Lauc, Gordan
Publicado 2014

Glycans Are a Novel Biomarker of Chronological and Biological Ages

por Krištić, Jasminka, Vučković, Frano, Menni, Cristina, Klarić, Lucija, Keser, Toma, Beceheli, Ivona, Pučić-Baković, Maja, Novokmet, Mislav, Mangino, Massimo, Thaqi, Kujtim, Rudan, Pavao, Novokmet, Natalija, Šarac, Jelena, Missoni, Saša, Kolčić, Ivana, Polašek, Ozren, Rudan, Igor, Campbell, Harry, Hayward, Caroline, Aulchenko, Yurii, Valdes, Ana, Wilson, James F., Gornik, Olga, Primorac, Dragan, Zoldoš, Vlatka, Spector, Tim, Lauc, Gordan
Publicado 2014