Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease

por Emdin, Connor A., Klarin, Derek, Natarajan, Pradeep, Florez, Jose C., Kathiresan, Sekar, Khera, Amit V.
Publicado 2017

Genetic predisposition to smoking in relation to 14 cardiovascular diseases

por Larsson, Susanna C, Mason, Amy M, Bäck, Magnus, Klarin, Derek, Damrauer, Scott M, Michaëlsson, Karl, Burgess, Stephen
Publicado 2020

Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses

por Yuan, Shuai, Titova, Olga E, Zhang, Ke, Chen, Jie, Li, Xue, Klarin, Derek, Åkesson, Agneta, Damrauer, Scott M, Larsson, Susanna C
Publicado 2023

Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

por Siewert, Katherine M, Klarin, Derek, Damrauer, Scott M, Chang, Kyong-Mi, Tsao, Philip S, Assimes, Themistocles L, Davey Smith, George, Voight, Benjamin F
Publicado 2020

Erratum to: Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

por Siewert, Katherine M, Klarin, Derek, Damrauer, Scott M, Chang, Kyong-Mi, Tsao, Philip S, Assimes, Themistocles L, Smith, George Davey, Voight, Benjamin F
Publicado 2020

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study

por Johnson, Kelsey E., Siewert, Katherine M., Klarin, Derek, Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Assimes, Themistocles L., Maxwell, Kara N., Voight, Benjamin F.
Publicado 2020

Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits

por Bone, William P., Siewert, Katherine M., Jha, Anupama, Klarin, Derek, Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Assimes, Themistocles L., Ritchie, Marylyn D., Voight, Benjamin F.
Publicado 2021

Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins

por Khetarpal, Sumeet A., Vitali, Cecilia, Levin, Michael G., Klarin, Derek, Park, Joseph, Pampana, Akhil, Millar, John S., Kuwano, Takashi, Sugasini, Dhavamani, Subbaiah, Papasani V., Billheimer, Jeffrey T., Natarajan, Pradeep, Rader, Daniel J.
Publicado 2021

Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study

por Levin, Michael G., Klarin, Derek, Assimes, Themistocles L., Freiberg, Matthew S., Ingelsson, Erik, Lynch, Julie, Natarajan, Pradeep, O’Donnell, Christopher, Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Damrauer, Scott M.
Publicado 2021

Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35

por Cullina, Sinead, Wojcik, Genevieve L., Shemirani, Ruhollah, Klarin, Derek, Gorman, Bryan R., Sorokin, Elena P., Gignoux, Christopher R., Belbin, Gillian M., Pyarajan, Saiju, Asgari, Samira, Tsao, Philip S., Damrauer, Scott M., Abul-Husn, Noura S., Kenny, Eimear E.
Publicado 2023

Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

por Gill, Dipender, Zuber, Verena, Dawson, Jesse, Pearson-Stuttard, Jonathan, Carter, Alice R., Sanderson, Eleanor, Karhunen, Ville, Levin, Michael G., Wootton, Robyn E., Klarin, Derek, Tsao, Philip S., Tsilidis, Konstantinos K., Damrauer, Scott M., Burgess, Stephen, Elliott, Paul
Publicado 2021

Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease

por Levin, Michael G., Zuber, Verena, Walker, Venexia M., Klarin, Derek, Lynch, Julie, Malik, Rainer, Aday, Aaron W., Bottolo, Leonardo, Pradhan, Aruna D., Dichgans, Martin, Chang, Kyong-Mi, Rader, Daniel J., Tsao, Philip S., Voight, Benjamin F., Gill, Dipender, Burgess, Stephen, Damrauer, Scott M.
Publicado 2021

Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials

por Gill, Dipender, Cameron, Alan C., Burgess, Stephen, Li, Xue, Doherty, Daniel J., Karhunen, Ville, Abdul-Rahim, Azmil H., Taylor-Rowan, Martin, Zuber, Verena, Tsao, Philip S., Klarin, Derek, Evangelou, Evangelos, Elliott, Paul, Damrauer, Scott M., Quinn, Terence J., Dehghan, Abbas, Theodoratou, Evropi, Dawson, Jesse, Tzoulaki, Ioanna
Publicado 2020

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

por Kranzler, Henry R., Zhou, Hang, Kember, Rachel L., Vickers Smith, Rachel, Justice, Amy C., Damrauer, Scott, Tsao, Philip S., Klarin, Derek, Baras, Aris, Reid, Jeffrey, Overton, John, Rader, Daniel J., Cheng, Zhongshan, Tate, Janet P., Becker, William C., Concato, John, Xu, Ke, Polimanti, Renato, Zhao, Hongyu, Gelernter, Joel
Publicado 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

por Kranzler, Henry R., Zhou, Hang, Kember, Rachel L., Smith, Rachel Vickers, Justice, Amy C., Damrauer, Scott, Tsao, Philip S., Klarin, Derek, Baras, Aris, Reid, Jeffrey, Overton, John, Rader, Daniel J., Cheng, Zhongshan, Tate, Janet P., Becker, William C., Concato, John, Xu, Ke, Polimanti, Renato, Zhao, Hongyu, Gelernter, Joel
Publicado 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

por Kranzler, Henry R., Zhou, Hang, Kember, Rachel L., Smith, Rachel Vickers, Justice, Amy C., Damrauer, Scott, Tsao, Philip S., Klarin, Derek, Baras, Aris, Reid, Jeffrey, Overton, John, Rader, Daniel J., Cheng, Zhongshan, Tate, Janet P., Becker, William C., Concato, John, Xu, Ke, Polimanti, Renato, Zhao, Hongyu, Gelernter, Joel
Publicado 2019

Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

por Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Publicado 2017

PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort

por Small, Aeron M., Huffman, Jennifer E., Klarin, Derek, Lynch, Julie A., Assimes, Themistocles, DuVall, Scott, Sun, Yan V., Shere, Labiba, Natarajan, Pradeep, Gaziano, Michael, Rader, Daniel J., Wilson, Peter W. F., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Casas, Juan P., Damrauer, Scott M.
Publicado 2020

Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci

por Bellomo, Tiffany R., Bone, William P., Chen, Brian Y., Gawronski, Katerina A. B., Zhang, David, Park, Joseph, Levin, Michael, Tsao, Noah, Klarin, Derek, Lynch, Julie, Assimes, Themistocles L., Gaziano, J. Michael, Wilson, Peter W., Cho, Kelly, Vujkovic, Marijana, O’Donnell, Christopher J., Chang, Kyong-Mi, Tsao, Philip S., Rader, Daniel J., Ritchie, Marylyn D., Damrauer, Scott M., Voight, Benjamin F.
Publicado 2022

Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

por Hellwege, Jacklyn N., Velez Edwards, Digna R., Giri, Ayush, Qiu, Chengxiang, Park, Jihwan, Torstenson, Eric S., Keaton, Jacob M., Wilson, O. D., Robinson-Cohen, Cassianne, Chung, Cecilia P., Roumie, Christianne L., Klarin, Derek, Damrauer, Scott M., DuVall, Scott L., Siew, Edward, Akwo, Elvis A., Wuttke, Matthias, Gorski, Mathias, Li, Man, Li, Yong, Gaziano, J. Michael, Wilson, Peter W. F., Tsao, Philip S., O’Donnell, Christopher J., Kovesdy, Csaba P., Pattaro, Cristian, Köttgen, Anna, Susztak, Katalin, Edwards, Todd L., Hung, Adriana M.
Publicado 2019