A mode of action-based probabilistic framework of dose-response assessment for nonmutagenic liver carcinogens: a case study of PCB-126

por Zhou, Yun, Chen, Qiran, Klaunig, James E, Shao, Kan
Publicado 2023

The effect of endurance training on non‐alcoholic fatty liver disease in mice

por Melo, Luma, Bilici, Merve, Hagar, Amit, Klaunig, James E.
Publicado 2021

Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans

por Heintz, Melissa M, Haws, Laurie C, Klaunig, James E, Cullen, John M, Thompson, Chad M
Publicado 2023

Antioxidant Vitamin C Prevents Decline in Endothelial Function during Sitting

por Thosar, Saurabh S., Bielko, Sylvanna L., Wiggins, Chad S., Klaunig, James E., Mather, Kieren J., Wallace, Janet P.
Publicado 2015

Dysbiosis in gastrointestinal pathophysiology: Role of the gut microbiome in Gulf War Illness

por Slevin, Elise, Koyama, Sachiko, Harrison, Kelly, Wan, Ying, Klaunig, James E., Wu, Chaodong, Shetty, Ashok K., Meng, Fanyin
Publicado 2023

Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

por Chappell, Grace A., Thompson, Chad M., Wolf, Jeffrey C., Cullen, John M., Klaunig, James E., Haws, Laurie C.
Publicado 2020

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models

por Fu, Xiao, Sluka, James P., Clendenon, Sherry G., Dunn, Kenneth W., Wang, Zemin, Klaunig, James E., Glazier, James A.
Publicado 2018

Induction of endogenous retroelements as a potential mechanism for mouse-specific drug-induced carcinogenicity

por Coskran, Timothy M., Jiang, Zhijie, Klaunig, James E., Mager, Dixie L., Obert, Leslie, Robertson, Andrew, Tsinoremas, Nicholas, Wang, Zemin, Gosink, Mark
Publicado 2017

A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder

por Wink, Logan K., Adams, Ryan, Wang, Zemin, Klaunig, James E., Plawecki, Martin H., Posey, David J., McDougle, Christopher J., Erickson, Craig A.
Publicado 2016

A computational model of liver tissue damage and repair

por Adhyapok, Priyom, Fu, Xiao, Sluka, James P., Clendenon, Sherry G., Sluka, Victoria D., Wang, Zemin, Dunn, Kenneth, Klaunig, James E., Glazier, James A.
Publicado 2020

Endothelial dysfunction in pathological processes of chronic liver disease during aging

por Wan, Ying, Li, Xuedong, Slevin, Elise, Harrison, Kelly, Li, Tian, Zhang, Yudian, Klaunig, James E., Wu, Chaodong, Shetty, Ashok K., Dong, X. Charlie, Meng, Fanyin
Publicado 2021

Linear low-dose extrapolation for noncancer health effects is the exception, not the rule

por Rhomberg, Lorenz R, Goodman, Julie E, Haber, Lynne T, Dourson, Michael, Andersen, Melvin E, Klaunig, James E, Meek, Bette, Price, Paul S, McClellan, Roger O, Cohen, Samuel M
Publicado 2011

PPARα and Effects of TCE

por Klaunig, James E., Babich, Michael A., Cook, Jon C., David, Raymond M., DeLuca, John G., McKee, Richard H., Peters, Jeffrey M., Roberts, Ruth A., Fenner-Crisp, Penelope A.
Publicado 2007

Contribution of Environment and Genetics to Pancreatic Cancer Susceptibility

por Hocevar, Barbara A., Kamendulis, Lisa M., Pu, Xinzhu, Perkins, Susan M., Wang, Zheng-Yu, Johnston, Erica L., DeWitt, John M., Li, Lang, Loehrer, Patrick J., Klaunig, James E., Chiorean, E. Gabriela
Publicado 2014

Evaluating Uncertainty to Strengthen Epidemiologic Data for Use in Human Health Risk Assessments

por Burns, Carol J., Wright, J. Michael, Pierson, Jennifer B., Bateson, Thomas F., Burstyn, Igor, Goldstein, Daniel A., Klaunig, James E., Luben, Thomas J., Mihlan, Gary, Ritter, Leonard, Schnatter, A. Robert, Symons, J. Morel, Don Yi, Kun
Publicado 2014

miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury

por Wan, Ying, Slevin, Elise, Koyama, Sachiko, Huang, Chiung-Kuei, Shetty, Ashok K, Li, Xuedong, Harrison, Kelly, Li, Tian, Zhou, Bingru, Lorenzo, Sugeily Ramos, Zhang, Yudian, Salinas, Jennifer Mata, Xu, Wenjuan, Klaunig, James E., Wu, Chaodong, Tsukamoto, Hidekazu, Meng, Fanyin
Publicado 2023

US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations

por Gori, Gio B., Aschner, Michael, Borgert, Christopher J., Cohen, Samuel M., Dietrich, Daniel R., Galli, Corrado L., Greim, Helmut, Heslop-Harrison, John S., Kacew, Sam, Kaminski, Norbert E., Klaunig, James E., Marquardt, Hans W.J., Pelkonen, Olavi, Roberts, Ruth, Savolainen, Kai M., Tsatsakis, Aristidis, Yamazaki, Hiroshi
Publicado 2023

A toxicogenomic approach for the risk assessment of the food contaminant acetamide

por Nault, Rance, Bals, Bryan, Teymouri, Farzaneh, Black, Michael B., Andersen, Melvin E., McMullen, Patrick D., Krishnan, Seetha, Kuravadi, Nagesh, Paul, Neetha, Kumar, Santhosh, Kannan, Kamala, Jayachandra, K.C., Alagappan, Lakshmanan, Patel, Bhavesh Dhirajlal, Bogen, Kenneth T., Gollapudi, Bhaskar B., Klaunig, James E., Zacharewski, Tim R., Bringi, Venkataraman
Publicado 2020

A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies

por Corton, J Christopher, Mitchell, Constance A, Auerbach, Scott, Bushel, Pierre, Ellinger-Ziegelbauer, Heidrun, Escobar, Patricia A, Froetschl, Roland, Harrill, Alison H, Johnson, Kamin, Klaunig, James E, Pandiri, Arun R, Podtelezhnikov, Alexei A, Rager, Julia E, Tanis, Keith Q, van der Laan, Jan Willem, Vespa, Alisa, Yauk, Carole L, Pettit, Syril D, Sistare, Frank D
Publicado 2022

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

por Goodson, William H., Lowe, Leroy, Carpenter, David O., Gilbertson, Michael, Manaf Ali, Abdul, Lopez de Cerain Salsamendi, Adela, Lasfar, Ahmed, Carnero, Amancio, Azqueta, Amaya, Amedei, Amedeo, Charles, Amelia K., Collins, Andrew R., Ward, Andrew, Salzberg, Anna C., Colacci, Anna Maria, Olsen, Ann-Karin, Berg, Arthur, Barclay, Barry J., Zhou, Binhua P., Blanco-Aparicio, Carmen, Baglole, Carolyn J., Dong, Chenfang, Mondello, Chiara, Hsu, Chia-Wen, Naus, Christian C., Yedjou, Clement, Curran, Colleen S., Laird, Dale W., Koch, Daniel C., Carlin, Danielle J., Felsher, Dean W., Roy, Debasish, Brown, Dustin G., Ratovitski, Edward, Ryan, Elizabeth P., Corsini, Emanuela, Rojas, Emilio, Moon, Eun-Yi, Laconi, Ezio, Marongiu, Fabio, Al-Mulla, Fahd, Chiaradonna, Ferdinando, Darroudi, Firouz, Martin, Francis L., Van Schooten, Frederik J., Goldberg, Gary S., Wagemaker, Gerard, Nangami, Gladys N., Calaf, Gloria M., Williams, Graeme P., Wolf, Gregory T., Koppen, Gudrun, Brunborg, Gunnar, Lyerly, H. Kim, Krishnan, Harini, Ab Hamid, Hasiah, Yasaei, Hemad, Sone, Hideko, Kondoh, Hiroshi, Salem, Hosni K., Hsu, Hsue-Yin, Park, Hyun Ho, Koturbash, Igor, Miousse, Isabelle R., Scovassi, A.Ivana, Klaunig, James E., Vondráček, Jan, Raju, Jayadev, Roman, Jesse, Wise, John Pierce, Whitfield, Jonathan R., Woodrick, Jordan, Christopher, Joseph A., Ochieng, Josiah, Martinez-Leal, Juan Fernando, Weisz, Judith, Kravchenko, Julia, Sun, Jun, Prudhomme, Kalan R., Narayanan, Kannan Badri, Cohen-Solal, Karine A., Moorwood, Kim, Gonzalez, Laetitia, Soucek, Laura, Jian, Le, D’Abronzo, Leandro S., Lin, Liang-Tzung, Li, Lin, Gulliver, Linda, McCawley, Lisa J., Memeo, Lorenzo, Vermeulen, Louis, Leyns, Luc, Zhang, Luoping, Valverde, Mahara, Khatami, Mahin, Romano, Maria Fiammetta, Chapellier, Marion, Williams, Marc A., Wade, Mark, Manjili, Masoud H., Lleonart, Matilde E., Xia, Menghang, Gonzalez Guzman, Michael J., Karamouzis, Michalis V., Kirsch-Volders, Micheline, Vaccari, Monica, Kuemmerle, Nancy B., Singh, Neetu, Cruickshanks, Nichola, Kleinstreuer, Nicole, van Larebeke, Nik, Ahmed, Nuzhat, Ogunkua, Olugbemiga, Krishnakumar, P.K., Vadgama, Pankaj, Marignani, Paola A., Ghosh, Paramita M., Ostrosky-Wegman, Patricia, Thompson, Patricia A., Dent, Paul, Heneberg, Petr, Darbre, Philippa, Leung, Po Sing, Nangia-Makker, Pratima, Cheng, Qiang (Shawn), Robey, R.Brooks, Al-Temaimi, Rabeah, Roy, Rabindra, Andrade-Vieira, Rafaela, Sinha, Ranjeet K., Mehta, Rekha, Vento, Renza, Di Fiore, Riccardo, Ponce-Cusi, Richard, Dornetshuber-Fleiss, Rita, Nahta, Rita, Castellino, Robert C., Palorini, Roberta, Hamid, Roslida A., Langie, Sabine A.S., Eltom, Sakina E., Brooks, Samira A., Ryeom, Sandra, Wise, Sandra S., Bay, Sarah N., Harris, Shelley A., Papagerakis, Silvana, Romano, Simona, Pavanello, Sofia, Eriksson, Staffan, Forte, Stefano, Casey, Stephanie C., Luanpitpong, Sudjit, Lee, Tae-Jin, Otsuki, Takemi, Chen, Tao, Massfelder, Thierry, Sanderson, Thomas, Guarnieri, Tiziana, Hultman, Tove, Dormoy, Valérian, Odero-Marah, Valerie, Sabbisetti, Venkata, Maguer-Satta, Veronique, Rathmell, W.Kimryn, Engström, Wilhelm, Decker, William K., Bisson, William H., Rojanasakul, Yon, Luqmani, Yunus, Chen, Zhenbang, Hu, Zhiwei
Publicado 2015