CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA

por Binda, Caroline S., Klaver, Bep, Berkhout, Ben, Das, Atze T.
Publicado 2020

Transient CRISPR-Cas Treatment Can Prevent Reactivation of HIV-1 Replication in a Latently Infected T-Cell Line

por Liu, Ye, Jeeninga, Rienk E., Klaver, Bep, Berkhout, Ben, Das, Atze T.
Publicado 2021

The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape

por Darcis, Gilles, Binda, Caroline S., Klaver, Bep, Herrera-Carrillo, Elena, Berkhout, Ben, Das, Atze T.
Publicado 2019

HIV-1 tolerates changes in A-count in a small segment of the pol gene

por Klaver, Bep, van der Velden, Yme, van Hemert, Formijn, van der Kuyl, Antoinette C., Berkhout, Ben
Publicado 2017

A conditionally replicating SIV variant that can be used to study the mechanism of protection conferred by live attenuated SIV vaccines

por Das, Atze T, Berry, Neil, Klaver, Bep, Page, Mark, Stebbings, Richard, Ferguson, Debbie, Cranage, Martin P, Almond, Neil, Berkhout, Ben
Publicado 2011

Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

por Das, Atze T, Klaver, Bep, Centlivre, Mireille, Harwig, Alex, Ooms, Marcel, Page, Mark, Almond, Neil, Yuan, Fang, Piatak, Mike, Lifson, Jeffrey D, Berkhout, Ben
Publicado 2008

Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine

por Berry, Neil, Manoussaka, Maria, Ham, Claire, Ferguson, Deborah, Tudor, Hannah, Mattiuzzo, Giada, Klaver, Bep, Page, Mark, Stebbings, Richard, Das, Atze T., Berkhout, Ben, Almond, Neil, Cranage, Martin P.
Publicado 2016

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against SIVmac239 wild-type challenge in a rhesus macaque model

por Berry, Neil, Das, Atze, Page, Mark, Tudor, Hannah, Robinson, Mark, Quartey-Papafio, Ruby, Elsley, William, Ferguson, Deborah, Li, Bo, Kleibeuker, Wendy, Klaver, Bep, Manoussaka, Maria, Stebbings, Richard, Cranage, Martin, Berkhout, Ben, Almond, Neil
Publicado 2009

A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses

por Chtarto, Abdelwahed, Humbert-Claude, Marie, Bockstael, Olivier, Das, Atze T, Boutry, Sébastien, Breger, Ludivine S, Klaver, Bep, Melas, Catherine, Barroso-Chinea, Pedro, Gonzalez-Hernandez, Tomas, Muller, Robert N, DeWitte, Olivier, Levivier, Marc, Lundberg, Cecilia, Berkhout, Ben, Tenenbaum, Liliane
Publicado 2016