Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro

por Sarkaria, Shawn M., Christopher, Matthew J., Klco, Jeffery M., Ley, Timothy J.
Publicado 2014

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation

por Malireddi, R.K. Subbarao, Gurung, Prajwal, Mavuluri, Jayadev, Dasari, Tejasvi Krishna, Klco, Jeffery M., Chi, Hongbo, Kanneganti, Thirumala-Devi
Publicado 2018

Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice

por Wartman, Lukas D., Welch, John S., Uy, Geoffrey L., Klco, Jeffery M., Lamprecht, Tamara, Varghese, Nobish, Nagarajan, Rakesh, Ley, Timothy J.
Publicado 2012

Notch Signaling in Acute Promyelocytic Leukemia

por Grieselhuber, Nicole R., Klco, Jeffery M., Verdoni, Angela M., Lamprecht, Tamara, Sarkaria, Shawn M., Wartman, Lukas D., Ley, Timothy J.
Publicado 2013

Clonal dynamics of donor-derived myelodysplastic syndrome after unrelated hematopoietic cell transplantation for high-risk pediatric B-lymphoblastic leukemia

por Schwartz, Jason R., Walsh, Michael P., Ma, Jing, Lamprecht, Tamara, Wang, Shuoguo, Wu, Gang, Raimondi, Susana, Triplett, Brandon M., Klco, Jeffery M.
Publicado 2018

CBFA2T3::GLIS2‐positive acute leukemia with RAM and mixed T/megakaryocytic phenotype

por Khanlari, Mahsa, Wang, Lu, Bolen, Christine Y, Otanez, Felipe Sebastian Bautista, Furtado, Larissa V., Key, Laura, Irwin, Lisa, Wang, Wei, Klco, Jeffery M.
Publicado 2023

Clinical impact of minimal residual disease in blood and bone marrow of children with acute myeloid leukemia

por Karol, Seth E., Coustan-Smith, Elaine, Pounds, Stanley, Wang, Lei, Inaba, Hiroto, Ribeiro, Raul C., Pui, Ching-Hon, Klco, Jeffery M., Rubnitz, Jeffrey E.
Publicado 2023

Rational biomarker development for the early and minimally invasive monitoring of AML

por Abdelhamed, Sherif, Butler, John T., Jung, Seul, Chen, Ding-Wen, Jenkins, Gaye, Gao, Lina, Lim, Jeong Y., Klco, Jeffery M., Horton, Terzah M., Kurre, Peter
Publicado 2021

Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells

por Thomas, Melvin E., Abdelhamed, Sherif, Hiltenbrand, Ryan, Schwartz, Jason R., Sakurada, Sadie Miki, Walsh, Michael, Song, Guangchun, Ma, Jing, Pruett-Miller, Shondra M., Klco, Jeffery M.
Publicado 2021

Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse

por Li, Cheng, Klco, Jeffery M., Helton, Nichole M., George, Daniel R., Mudd, Jacqueline L., Miller, Christopher A., Lu, Charles, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Wilson, Richard K., Ley, Timothy J.
Publicado 2015

CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells

por Hebbar, Nikhil, Epperly, Rebecca, Vaidya, Abishek, Thanekar, Unmesha, Moore, Sarah E., Umeda, Masayuki, Ma, Jing, Patil, Sagar L., Langfitt, Deanna, Huang, Sujuan, Cheng, Cheng, Klco, Jeffery M., Gottschalk, Stephen, Velasquez, M. Paulina
Publicado 2022

The genomic landscape of pediatric myelodysplastic syndromes

por Schwartz, Jason R., Ma, Jing, Lamprecht, Tamara, Walsh, Michael, Wang, Shuoguo, Bryant, Victoria, Song, Guangchun, Wu, Gang, Easton, John, Kesserwan, Chimene, Nichols, Kim E., Mullighan, Charles G., Ribeiro, Raul C., Klco, Jeffery M.
Publicado 2017

Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice

por Abdelhamed, Sherif, Thomas, Melvin E., Westover, Tamara, Umeda, Masayuki, Xiong, Emily, Rolle, Chandra, Walsh, Michael P., Wu, Huiyun, Schwartz, Jason R., Valentine, Virginia, Valentine, Marcus, Pounds, Stanley, Ma, Jing, Janke, Laura J., Klco, Jeffery M.
Publicado 2022

SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia

por Marrero, Richard J., Cao, Xueyuan, Wu, Huiyun, Elsayed, Abdelrahman H., Klco, Jeffery M., Ribeiro, Raul C., Rubnitz, Jeffrey E., Ma, Xiaotu, Meshinchi, Soheil, Aplenc, Richard, Kolb, E. Anders, Ries, Rhonda E., Alonzo, Todd A., Pounds, Stanley B., Lamba, Jatinder K.
Publicado 2023

Germline SAMD9 Mutation in Siblings with Monosomy 7 and Myelodysplastic Syndrome

por Schwartz, Jason R., Wang, Shuoguo, Ma, Jing, Lamprecht, Tamara, Walsh, Michael, Song, Guangchun, Raimondi, Susana C., Wu, Gang, Walsh, Michael F., McGee, Rose B., Kesserwan, Chimene, Nichols, Kim E., Cauff, Brian E., Ribeiro, Raul C., Wlodarski, Marcin, Klco, Jeffery M.
Publicado 2017

SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data

por Davis, Eric M., Sun, Yu, Liu, Yanling, Kolekar, Pandurang, Shao, Ying, Szlachta, Karol, Mulder, Heather L., Ren, Dongren, Rice, Stephen V., Wang, Zhaoming, Nakitandwe, Joy, Gout, Alexander M., Shaner, Bridget, Hall, Salina, Robison, Leslie L., Pounds, Stanley, Klco, Jeffery M., Easton, John, Ma, Xiaotu
Publicado 2021

Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis

por Umeda, Masayuki, Ma, Jing, Westover, Tamara, Ni, Yonghui, Song, Guangchun, Maciaszek, Jamie L., Rusch, Michael, Rahbarinia, Delaram, Foy, Scott, Huang, Benjamin J., Walsh, Michael P., Kumar, Priyadarshini, Liu, Yanling, Fan, Yiping, Wu, Gang, Baker, Sharyn D., Ma, Xiaotu, Wang, Lu, Rubnitz, Jeffrey E., Pounds, Stanley, Klco, Jeffery M.
Publicado 2023

Engineering naturally occurring CD7(−) T cells for the immunotherapy of hematological malignancies

por Freiwan, Abdullah, Zoine, Jaquelyn T., Crawford, Jeremy Chase, Vaidya, Abishek, Schattgen, Stefan A., Myers, Jacquelyn A., Patil, Sagar L., Khanlari, Mahsa, Inaba, Hiroto, Klco, Jeffery M., Mullighan, Charles G., Krenciute, Giedre, Chockley, Peter J., Naik, Swati, Langfitt, Deanna M., Mamonkin, Maksim, Obeng, Esther A., Thomas, Paul G., Gottschalk, Stephen, Velasquez, M. Paulina
Publicado 2022

The Role of TP53 Mutations in the Origin and Evolution of Therapy-Related AML

por Wong, Terrence N., Ramsingh, Giridharan, Young, Andrew L., Miller, Christopher A., Touma, Waseem, Welch, John S., Lamprecht, Tamara L., Shen, Dong, Hundal, Jasreet, Fulton, Robert S., Heath, Sharon, Baty, Jack D., Klco, Jeffery M., Ding, Li, Mardis, Elaine R., Westervelt, Peter, DiPersio, John F., Walter, Matthew J., Graubert, Timothy A., Ley, Timothy J., Druley, Todd, Link, Daniel C., Wilson, Richard K.
Publicado 2014

The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms

por Schwartz, Jason R., Ma, Jing, Kamens, Jennifer, Westover, Tamara, Walsh, Michael P., Brady, Samuel W., Robert Michael, J., Chen, Xiaolong, Montefiori, Lindsey, Song, Guangchun, Wu, Gang, Wu, Huiyun, Branstetter, Cristyn, Hiltenbrand, Ryan, Walsh, Michael F., Nichols, Kim E., Maciaszek, Jamie L., Liu, Yanling, Kumar, Priyadarshini, Easton, John, Newman, Scott, Rubnitz, Jeffrey E., Mullighan, Charles G., Pounds, Stanley, Zhang, Jinghui, Gruber, Tanja, Ma, Xiaotu, Klco, Jeffery M.
Publicado 2021