T cell receptor‐based cancer immunotherapy: Emerging efficacy and pathways of resistance

por Chandran, Smita S., Klebanoff, Christopher A.
Publicado 2019

Shared cancer neoantigens: Making private matters public

por Klebanoff, Christopher A., Wolchok, Jedd D.
Publicado 2018

Fas expression in memory CD8+ T cell subsets augments cellular differentiation and effector function

por Yamamoto, Tori, Leonardi, Anthony, Liu, Hui, Wang, Ena, Gattinoni, Luca, Cruz, Anthony, Ouyang, Claudia, Siegel, Richard, Restifo, Nicholas, Klebanoff, Christopher A
Publicado 2015

Elevated potassium levels suppress T cell activation within tumors

por Eil, Robert L, Roychoudhuri, Rahul, Clever, David, Patel, Shashank, Sukumar, Madhu, Pan, Jenny H, Palmer, Douglas, Klebanoff, Christopher A, Restifo, Nicholas P
Publicado 2015

Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells

por Klebanoff, Christopher A, Spencer, Sean, Roychoudhuri, Rahu, Ji, Yun, Sukumar, Madhu, Muranski, Pawel, Napoli, Joseph L, Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P
Publicado 2013

Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells

por Williams, Chad M., Schonnesen, Alexandra A., Zhang, Shu-Qi, Ma, Ke-Yue, He, Chenfeng, Yamamoto, Tori, Eckhardt, S. Gail, Klebanoff, Christopher A., Jiang, Ning
Publicado 2017

Cish actively silences tcr signaling in CD8+ T cells to maintain tumor tolerance

por Palmer, Douglas, Guittard, Geoff, Franco, Zulmarie, Patel, Shashank, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Eil, Robert L, Clever, David, Balagopalan, Lakshmi, Roychoudhuri, Rahul, Samelson, Larry, Restifo, Nicholas
Publicado 2015

Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer

por Sukumar, Madhusudhanan, Liu, Jie, Patel, Shashank J, Klebanoff, Christopher A, Mehta, Gautam, Roychoudhuri, Rahul, Crompton, Joseph, Clever, David, Gattinoni, Luca, Muranski, Pawel, Finkel, Toren, Restifo, Nicholas
Publicado 2015

Immunotherapy generates selective pressure for acquisition of immunogenic neoantigens in escape tumors

por Pan, Jenny H, Vodnala, Suman, Eil, Robert L, Yu, Zhiya, Gartner, Jared J, Clever, David, Roychoudhuri, Rahul, Patel, Shashank J, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Yamamoto, Tori, Restifo, Nicholas P
Publicado 2015

Risk stratification of cardiac metastases using late gadolinium enhancement cardiovascular magnetic resonance: prognostic impact of hypo-enhancement evidenced tumor avascularity

por Chan, Angel T., Dinsfriend, William, Kim, Jiwon, Yum, Brian, Sultana, Razia, Klebanoff, Christopher A., Plodkowski, Andrew, Perez Johnston, Rocio, Ginsberg, Michelle S., Liu, Jennifer, Kim, Raymond J., Steingart, Richard, Weinsaft, Jonathan W.
Publicado 2021

A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers

por Lu, Yong-Chen, Parker, Linda, Lu, Tangying, Zheng, Zhili, Yao, Xin, Robbins, Paul F, van der Bruggen, Pierre, Klebanoff, Christopher A, Hinrichs, Christian S, Goff, Stephanie, Sherry, Richard, Kammula, Udai, Yang, James C, Rosenberg, Steven A
Publicado 2015

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8(+) T cells

por Gattinoni, Luca, Finkelstein, Steven E., Klebanoff, Christopher A., Antony, Paul A., Palmer, Douglas C., Spiess, Paul J., Hwang, Leroy N., Yu, Zhiya, Wrzesinski, Claudia, Heimann, David M., Surh, Charles D., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado 2005

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits CD8(+) T cell memory formation

por Ji, Yun, Pos, Zoltan, Rao, Mahadev, Klebanoff, Christopher A., Yu, Zhiya, Sukumar, Madhusudhanan, Reger, Robert N., Palmer, Douglas C., Borman, Zachary A., Muranski, Pawel, Wang, Ena, Schrump, David S., Marincola, Francesco M., Restifo, Nicholas P., Gattinoni, Luca
Publicado 2011

Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

por Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2016

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

por Cruz, Anthony C., Ramaswamy, Madhu, Ouyang, Claudia, Klebanoff, Christopher A., Sengupta, Prabuddha, Yamamoto, Tori N., Meylan, Françoise, Thomas, Stacy K., Richoz, Nathan, Eil, Robert, Price, Susan, Casellas, Rafael, Rao, V. Koneti, Lippincott-Schwartz, Jennifer, Restifo, Nicholas P., Siegel, Richard M.
Publicado 2016

Ionic immune suppression within the tumour microenvironment limits T cell effector function

por Eil, Robert, Vodnala, Suman K, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Pan, Jenny H, Palmer, Douglas C, Gros, Alena, Yamamoto, Tori N, Patel, Shashank J, Guittard, Geoffrey C, Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S, Linehan, W Marston, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado 2016

Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy)

por Ascierto, Paolo A., Brugarolas, James, Buonaguro, Luigi, Butterfield, Lisa H., Carbone, David, Daniele, Bruno, Ferris, Robert, Fox, Bernard A., Galon, Jérôme, Gridelli, Cesare, Kaufman, Howard L., Klebanoff, Christopher A., Melero, Ignacio, Nathan, Paul, Paulos, Chrystal M., Ruella, Marco, Sullivan, Ryan, Zarour, Hassane, Puzanov, Igor
Publicado 2018

Cish actively silences TCR signaling in CD8(+) T cells to maintain tumor tolerance

por Palmer, Douglas C., Guittard, Geoffrey C., Franco, Zulmarie, Crompton, Joseph G., Eil, Robert L., Patel, Shashank J., Ji, Yun, Van Panhuys, Nicholas, Klebanoff, Christopher A., Sukumar, Madhusudhanan, Clever, David, Chichura, Anna, Roychoudhuri, Rahul, Varma, Rajat, Wang, Ena, Gattinoni, Luca, Marincola, Francesco M., Balagopalan, Lakshmi, Samelson, Lawrence E., Restifo, Nicholas P.
Publicado 2015

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8(+) T Cells

por Overwijk, Willem W., Theoret, Marc R., Finkelstein, Steven E., Surman, Deborah R., de Jong, Laurina A., Vyth-Dreese, Florry A., Dellemijn, Trees A., Antony, Paul A., Spiess, Paul J., Palmer, Douglas C., Heimann, David M., Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Feigenbaum, Lionel, Kruisbeek, Ada M., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado 2003

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA

por Chandran, Smita S., Ma, Jiaqi, Klatt, Martin G., Dündar, Friederike, Bandlamudi, Chaitanya, Razavi, Pedram, Wen, Hannah Y., Weigelt, Britta, Zumbo, Paul, Fu, Si Ning, Banks, Lauren B., Yi, Fei, Vercher, Enric, Etxeberria, Inaki, Bestman, Watchain D., Da Cruz Paula, Arnaud, Aricescu, Ilinca S., Drilon, Alexander, Betel, Doron, Scheinberg, David A., Baker, Brian M., Klebanoff, Christopher A.
Publicado 2022