Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer

por Kleeman, Sam O., Leedham, Simon J.
Publicado 2020

Migraine as an Entrapment Neuropathy? Epidemiological and Genetic Associations with Carpal Tunnel Syndrome

por Wiberg, Akira, Lucey, Maria, Kleeman, Sam, Ng, Michael, Furniss, Dominic
Publicado 2022

Genome-wide association analysis and replication in 810,625 individuals with varicose veins

por Ahmed, Waheed-Ul-Rahman, Kleeman, Sam, Ng, Michael, Wang, Wei, Auton, Adam, Lee, Regent, Handa, Ashok, Zondervan, Krina T., Wiberg, Akira, Furniss, Dominic
Publicado 2022

Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study

por Patel, Benjamin, Kleeman, Sam O, Neavin, Drew, Powell, Joseph, Baskozos, Georgios, Ng, Michael, Ahmed, Waheed-Ul-Rahman, Bennett, David L, Schmid, Annina B, Furniss, Dominic, Wiberg, Akira
Publicado 2022

Cystatin C is associated with adverse COVID-19 outcomes in diverse populations

por Kleeman, Sam O., Cordioli, Mattia, Timmers, Paul R.H. J., Khan, Atlas, Tober-Lau, Pinkus, Kurth, Florian, Demichev, Vadim, Meyer, Hannah V., Wilson, James F., Ralser, Markus, Kiryluk, Krzysztof, Ganna, Andrea, Baillie, Kenneth, Janowitz, Tobias
Publicado 2022

Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia

por Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E., Kleeman, Sam O., Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R., Connell, Claire M., Lukey, Michael J., White, Eileen P., Coll, Anthony P., Venkitaraman, Ashok R., Janowitz, Tobias
Publicado 2023

Selection and Application of Tissue microRNAs for Nonendoscopic Diagnosis of Barrett’s Esophagus

por Li, Xiaodun, Kleeman, Sam, Coburn, Sally B., Fumagalli, Carlo, Perner, Juliane, Jammula, Sriganesh, Pfeiffer, Ruth M., Orzolek, Linda, Hao, Haiping, Taylor, Philip R., Miremadi, Ahmad, Galeano-Dalmau, Núria, Lao-Sirieix, Pierre, Tennyson, Maria, MacRae, Shona, Cook, Michael B., Fitzgerald, Rebecca C.
Publicado 2018

Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia

por Petruzzelli, Michele, Ferrer, Miriam, Schuijs, Martijn J., Kleeman, Sam O., Mourikis, Nicholas, Hall, Zoe, Perera, David, Raghunathan, Shwethaa, Vacca, Michele, Gaude, Edoardo, Lukey, Michael J., Jodrell, Duncan I., Frezza, Christian, Wagner, Erwin F., Venkitaraman, Ashok R., Halim, Timotheus Y. F., Janowitz, Tobias
Publicado 2022

Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

por Kleeman, Sam O, Koelzer, Viktor H, Jones, Helen JS, Vazquez, Ester Gil, Davis, Hayley, East, James E, Arnold, Roland, Koppens, Martijn AJ, Blake, Andrew, Domingo, Enric, Cunningham, Chris, Beggs, Andrew D, Pestinger, Valerie, Loughrey, Maurice B, Wang, Lai-Mun, Lannagan, Tamsin RM, Woods, Susan L, Worthley, Daniel, Consortium, S:CORT, Tomlinson, Ian, Dunne, Philip D, Maughan, Timothy, Leedham, Simon J
Publicado 2020

Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy

por Kleeman, Sam O., Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef J.R.A., Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz G.N., Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan L.M., Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H., Walker, Brian R., Meyer, Hannah V., Janowitz, Tobias
Publicado 2023

Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial

por Brennan, Christina M, Nadella, Sandeep, Zhao, Xiang, Dima, Richard J, Jordan-Martin, Nicole, Demestichas, Breanna R, Kleeman, Sam O, Ferrer, Miriam, von Gablenz, Eva Carlotta, Mourikis, Nicholas, Rubin, Michael E, Adnani, Harsha, Lee, Hassal, Ha, Taehoon, Prum, Soma, Schleicher, Cheryl B, Fox, Sharon S, Ryan, Michael G, Pili, Christina, Goldberg, Gary, Crawford, James M, Goodwin, Sara, Zhang, Xiaoyue, Preall, Jonathan B, Costa, Ana S H, Conigliaro, Joseph, Masci, Joseph R, Yang, Jie, Tuveson, David A, Tracey, Kevin J, Janowitz, Tobias
Publicado 2022