Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma

por Havranek, Ondrej, Kleiblova, Petra, Hojny, Jan, Lhota, Filip, Soucek, Pavel, Trneny, Marek, Kleibl, Zdenek
Publicado 2015

CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate

por Stolarova, Lenka, Kleiblova, Petra, Janatova, Marketa, Soukupova, Jana, Zemankova, Petra, Macurek, Libor, Kleibl, Zdenek
Publicado 2020

Importance of Germline and Somatic Alterations in Human MRE11, RAD50, and NBN Genes Coding for MRN Complex

por Otahalova, Barbora, Volkova, Zuzana, Soukupova, Jana, Kleiblova, Petra, Janatova, Marketa, Vocka, Michal, Macurek, Libor, Kleibl, Zdenek
Publicado 2023

Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic

por Janatova, Marketa, Soukupova, Jana, Stribrna, Jana, Kleiblova, Petra, Vocka, Michal, Boudova, Petra, Kleibl, Zdenek, Pohlreich, Petr
Publicado 2015

Genetic and Preventive Services for Hereditary Breast and Ovarian Cancer in the Czech Republic

por Foretova, Lenka, Petrakova, Katarina, Palacova, Marketa, Kalabova, Renata, Navratilova, Marie, Lukesova, Miroslava, Vasickova, Petra, Machackova, Eva, Kleibl, Zdenek, Pohlreich, Petr
Publicado 2006

High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area

por Pohlreich, Petr, Zikan, Michal, Stribrna, Jana, Kleibl, Zdenek, Janatova, Marketa, Kotlas, Jaroslav, Zidovska, Jana, Novotny, Jan, Petruzelka, Lubos, Szabo, Csilla, Matous, Bohuslav
Publicado 2005

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

por Kleiblova, Petra, Shaltiel, Indra A., Benada, Jan, Ševčík, Jan, Pecháčková, Soňa, Pohlreich, Petr, Voest, Emile E., Dundr, Pavel, Bartek, Jiri, Kleibl, Zdenek, Medema, René H., Macurek, Libor
Publicado 2013

A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants

por Ticha, Ivana, Hojny, Jan, Michalkova, Romana, Kodet, Ondrej, Krkavcova, Eva, Hajkova, Nikola, Nemejcova, Kristyna, Bartu, Michaela, Jaksa, Radek, Dura, Miroslav, Kanwal, Madiha, Martinikova, Andra S., Macurek, Libor, Zemankova, Petra, Kleibl, Zdenek, Dundr, Pavel
Publicado 2019

Validation of CZECANCA (CZEch CAncer paNel for Clinical Application) for targeted NGS-based analysis of hereditary cancer syndromes

por Soukupova, Jana, Zemankova, Petra, Lhotova, Klara, Janatova, Marketa, Borecka, Marianna, Stolarova, Lenka, Lhota, Filip, Foretova, Lenka, Machackova, Eva, Stranecky, Viktor, Tavandzis, Spiros, Kleiblova, Petra, Vocka, Michal, Hartmannova, Hana, Hodanova, Katerina, Kmoch, Stanislav, Kleibl, Zdenek
Publicado 2018

Identification of Germline Mutations in Melanoma Patients with Early Onset, Double Primary Tumors, or Family Cancer History by NGS Analysis of 217 Genes

por Stolarova, Lenka, Jelinkova, Sandra, Storchova, Radka, Machackova, Eva, Zemankova, Petra, Vocka, Michal, Kodet, Ondrej, Kral, Jan, Cerna, Marta, Volkova, Zuzana, Janatova, Marketa, Soukupova, Jana, Stranecky, Viktor, Dundr, Pavel, Foretova, Lenka, Macurek, Libor, Kleiblova, Petra, Kleibl, Zdenek
Publicado 2020

Genetic analysis of subsequent second primary malignant neoplasms in long-term pancreatic cancer survivors suggests new potential hereditary genetic alterations

por Lovecek, Martin, Janatova, Marketa, Skalicky, Pavel, Zemanek, Tomas, Havlik, Roman, Ehrmann, Jiri, Strouhal, Ondrej, Zemankova, Petra, Lhotova, Klara, Borecka, Marianna, Soukupova, Jana, Svebisova, Hana, Soucek, Pavel, Hlavac, Viktor, Kleibl, Zdenek, Neoral, Cestmir, Melichar, Bohuslav, Mohelnikova-Duchonova, Beatrice
Publicado 2019

Low Frequency of Cancer-Predisposition Gene Mutations in Liver Transplant Candidates with Hepatocellular Carcinoma

por Horackova, Klara, Frankova, Sona, Zemankova, Petra, Nehasil, Petr, Cerna, Marta, Neroldova, Magdalena, Otahalova, Barbora, Kral, Jan, Hovhannisyan, Milena, Stranecky, Viktor, Zima, Tomas, Safarikova, Marketa, Kalousova, Marta, Consortium, CZECANCA, Novotny, Jan, Sperl, Jan, Borecka, Marianna, Jelinkova, Sandra, Vocka, Michal, Janatova, Marketa, Kleiblova, Petra, Kleibl, Zdenek, Jirsa, Milan, Soukupova, Jana
Publicado 2022

Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon

por Burocziova, Monika, Burdova, Kamila, Martinikova, Andra S., Kasparek, Petr, Kleiblova, Petra, Danielsen, Stine A., Borecka, Marianna, Jenikova, Gabriela, Janečková, Lucie, Pavel, Jozef, Zemankova, Petra, Schneiderova, Michaela, Schwarzova, Lucie, Ticha, Ivana, Sun, Xiao-Feng, Jiraskova, Katerina, Liska, Vaclav, Vodickova, Ludmila, Vodicka, Pavel, Sedlacek, Radislav, Kleibl, Zdenek, Lothe, Ragnhild A., Korinek, Vladimír, Macurek, Libor
Publicado 2019

Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer

por Rump, Andreas, Benet-Pages, Anna, Schubert, Steffen, Kuhlmann, Jan Dominik, Janavičius, Ramūnas, Macháčková, Eva, Foretová, Lenka, Kleibl, Zdenek, Lhota, Filip, Zemankova, Petra, Betcheva-Krajcir, Elitza, Mackenroth, Luisa, Hackmann, Karl, Lehmann, Janin, Nissen, Anke, DiDonato, Nataliya, Opitz, Romy, Thiele, Holger, Kast, Karin, Wimberger, Pauline, Holinski-Feder, Elke, Emmert, Steffen, Schröck, Evelin, Klink, Barbara
Publicado 2016

Estrogen Receptor Status Oppositely Modifies Breast Cancer Prognosis in BRCA1/BRCA2 Mutation Carriers Versus Non-Carriers

por Vocka, Michal, Zimovjanova, Martina, Bielcikova, Zuzana, Tesarova, Petra, Petruzelka, Lubos, Mateju, Martin, Krizova, Ludmila, Kotlas, Jaroslav, Soukupova, Jana, Janatova, Marketa, Zemankova, Petra, Kleiblova, Petra, Novotny, Jan, Konopasek, Bohuslav, Chodacka, Martina, Brychta, Milan, Sochor, Marek, Smejkalova-Musilova, Denisa, Cmejlova, Vlastimila, Kozevnikovova, Renata, Miskarova, Lenka, Argalacsova, Sona, Stolarova, Lenka, Lhotova, Klara, Borecka, Marianna, Kleibl, Zdenek
Publicado 2019

Multigene Panel Germline Testing of 1333 Czech Patients with Ovarian Cancer

por Lhotova, Klara, Stolarova, Lenka, Zemankova, Petra, Vocka, Michal, Janatova, Marketa, Borecka, Marianna, Cerna, Marta, Jelinkova, Sandra, Kral, Jan, Volkova, Zuzana, Urbanova, Marketa, Kleiblova, Petra, Machackova, Eva, Foretova, Lenka, Hazova, Jana, Vasickova, Petra, Lhota, Filip, Koudova, Monika, Cerna, Leona, Tavandzis, Spiros, Indrakova, Jana, Hruskova, Lucie, Kosarova, Marcela, Vrtel, Radek, Stranecky, Viktor, Kmoch, Stanislav, Zikan, Michal, Macurek, Libor, Kleibl, Zdenek, Soukupova, Jana
Publicado 2020

Prevalence of Germline Pathogenic Variants in Cancer Predisposing Genes in Czech and Belgian Pancreatic Cancer Patients

por Wieme, Greet, Kral, Jan, Rosseel, Toon, Zemankova, Petra, Parton, Bram, Vocka, Michal, Van Heetvelde, Mattias, Kleiblova, Petra, Blaumeiser, Bettina, Soukupova, Jana, van den Ende, Jenneke, Nehasil, Petr, Tejpar, Sabine, Borecka, Marianna, Gómez García, Encarna B., Blok, Marinus J., Safarikova, Marketa, Kalousova, Marta, Geboes, Karen, De Putter, Robin, Poppe, Bruce, De Leeneer, Kim, Kleibl, Zdenek, Janatova, Marketa, Claes, Kathleen B. M.
Publicado 2021

Germline multigene panel testing of patients with endometrial cancer

por Kral, Jan, Jelinkova, Sandra, Zemankova, Petra, Vocka, Michal, Borecka, Marianna, Cerna, Leona, Cerna, Marta, Dostalek, Lukas, Duskova, Petra, Foretova, Lenka, Havranek, Ondrej, Horackova, Klara, Hovhannisyan, Milena, Chvojka, Stepan, Kalousova, Marta, Kosarova, Marcela, Koudova, Monika, Krutilkova, Vera, Machackova, Eva, Nehasil, Petr, Novotny, Jan, Otahalova, Barbora, Puchmajerova, Alena, Safarikova, Marketa, Slama, Jiri, Stranecky, Viktor, Subrt, Ivan, Tavandzis, Spiros, Zikan, Michal, Zima, Tomas, Soukupova, Jana, Kleiblova, Petra, Kleibl, Zdenek, Janatova, Marketa
Publicado 2023

The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases

por Figlioli, Gisella, Kvist, Anders, Tham, Emma, Soukupova, Jana, Kleiblova, Petra, Muranen, Taru A, Andrieu, Nadine, Azzollini, Jacopo, Balmaña, Judith, Barroso, Alicia, Benítez, Javier, Bertelsen, Birgitte, Blanco, Ana, Bonanni, Bernardo, Borg, Åke, Brunet, Joan, Calistri, Daniele, Calvello, Mariarosaria, Chvojka, Stepan, Cortesi, Laura, Darder, Esther, Del Valle, Jesús, Diez, Orland, Consortium, ENIGMA, Eon-Marchais, Séverine, Fostira, Florentia, Gensini, Francesca, Houdayer, Claude, Janatova, Marketa, Kiiski, Johanna I, Konstantopoulou, Irene, Kubelka-Sabit, Katerina, Lázaro, Conxi, Lesueur, Fabienne, Manoukian, Siranoush, Marcinkute, Ruta, Mickys, Ugnius, Moncoutier, Virginie, Myszka, Aleksander, Nguyen-Dumont, Tu, Nielsen, Finn Cilius, Norvilas, Rimvydas, Olah, Edith, Osorio, Ana, Papi, Laura, Peissel, Bernard, Peixoto, Ana, Plaseska-Karanfilska, Dijana, Pócza, Timea, Rossing, Maria, Rudaitis, Vilius, Santamariña, Marta, Santos, Catarina, Smichkoska, Snezhana, Southey, Melissa C, Stoppa-Lyonnet, Dominique, Teixeira, Manuel, Törngren, Therese, Toss, Angela, Urioste, Miguel, Vega, Ana, Vlckova, Zdenka, Yannoukakos, Drakoulis, Zampiga, Valentina, Kleibl, Zdenek, Radice, Paolo, Nevanlinna, Heli, Ehrencrona, Hans, Janavicius, Ramunas, Peterlongo, Paolo
Publicado 2020

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

por Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K., Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J., Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S., Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D. Gareth R., Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B., González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N.A., Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L., Nevanlinna, Heli, Olson, Janet E., Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E., Rosseel, Toon, Ruddy, Kathryn J., Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E., Trentham-Dietz, Amy, Vachon, Celine M., Volk, Alexander E., Weber-Lassalle, Nana, Weitzel, Jeffrey N., Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B., Vega, Ana, Rossing, Maria, Del Valle, Jesús, De Nicolo, Arcangela, Hahnen, Eric, Claes, Kathleen B.M., Ngeow, Joanne, Momozawa, Yukihide, James, Paul A., Couch, Fergus J., Macurek, Libor, Kleibl, Zdenek
Publicado 2023