A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation

por Kleikers, Pamela WM., Hooijmans, Carlijn, Göb, Eva, Langhauser, Friederike, Rewell, Sarah SJ., Radermacher, Kim, Ritskes-Hoitinga, Merel, Howells, David W., Kleinschnitz, Christoph, HHW Schmidt, Harald
Publicado 2015

A systems biology approach to cGMP suggests a prominent role for sGC in stroke: Validation by mechanism-based activation of apo-sGC in non-steal dosing coveys neuroprotection and i...

por Casas, Ana I, Langhauser, Friederike, Dao, Vu Thao-Vi, Guney, Emre, Kleikers, Pamela WM, López, Manuela García, Menche, Jörg, Barabási, Albert-László, Kleinschnitz, Christoph, Schmidt, Harald HHW
Publicado 2015