The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer

por Gouttefangeas, Cécile, Klein, Reinhild, Maia, Ana
Publicado 2023

Effect of buckminsterfullerenes on cells of the innate and adaptive immune system: an in vitro study with human peripheral blood mononuclear cells

por Bunz, Hanno, Plankenhorn, Sandra, Klein, Reinhild
Publicado 2012

Analysis of the clinical relevance of antimitochondrial antibodies to the β- and γ-subunits of the F(1)F(0)-ATPase in patients with primary biliary cirrhosis

por Nann, Dominik, Berg, Christoph P, Preuß, Beate E, Klein, Reinhild
Publicado 2012

Antibodies to the Muscarinic Acetylcholine Receptor M3 in Primary Biliary Cholangitis Inhibit Receptor Function on Cholangiocytes

por Mayer, Christian, Preuss, Beate, Grottenthaler, Julia, Berg, Christoph, Klein, Reinhild
Publicado 2020

Functionally Active Antibodies to the Angiotensin II Type 1-Receptor Measured by a Luminometric Bioassay Do Not Correlate With Clinical Manifestations in Systemic Sclerosis: A Comp...

por Bankamp, Lukas, Preuß, Beate, Pecher, Ann-Christin, Beucke, Nicola, Henes, Jörg, Klein, Reinhild
Publicado 2021

Sulphite oxidase (SO) – a mitochondrial autoantigen as target for humoral and cellular immune reactions in primary sclerosing cholangitis

por Preuß, Beate E., Berg, Christoph P., Werner, Christoph, Plankenhorn, Sandra, Malek, Nisar P., Klein, Reinhild
Publicado 2018

HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation

por Roerden, Malte, Nelde, Annika, Heitmann, Jonas S., Klein, Reinhild, Rammensee, Hans-Georg, Bethge, Wolfgang A., Walz, Juliane S.
Publicado 2020

COVID-19 in Autoinflammatory Diseases with Immunosuppressive Treatment

por Welzel, Tatjana, Samba, Samuel Dembi, Klein, Reinhild, van den Anker, Johannes N., Kuemmerle-Deschner, Jasmin B.
Publicado 2021

Cholestatic Liver Disease after Rituximab and Adalimumab and the Possible Role of Cross-Reacting Antibodies to Fab 2 Fragments

por Latus, Joerg, Klein, Reinhild, Koetter, Ina, Schwab, Matthias, Fritz, Peter, Kimmel, Martin, Alscher, M. Dominik, Braun, Niko
Publicado 2013

Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy

por Eichholz, Thomas, Arendt, Anne-Marie, Holzer, Ursula, Seitz, Christian, Rabsteyn, Armin, Ganzenmueller, Tina, Klein, Reinhild, Walz, Juliane, Lang, Peter
Publicado 2022

Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlatio...

por Hervier, Baptiste, Ribon, Matthieu, Tarantino, Nadine, Mussard, Julie, Breckler, Magali, Vieillard, Vincent, Amoura, Zahir, Steinle, Alexander, Klein, Reinhild, Kötter, Ina, Decker, Patrice
Publicado 2021

Inhibition of effector B cells by ibrutinib in systemic sclerosis

por Einhaus, Jakob, Pecher, Ann-Christin, Asteriti, Elisa, Schmid, Hannes, Secker, Kathy-Ann, Duerr-Stoerzer, Silke, Keppeler, Hildegard, Klein, Reinhild, Schneidawind, Corina, Henes, Joerg, Schneidawind, Dominik
Publicado 2020

Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis

por Pecher, Ann-Christin, Kettemann, Felix, Asteriti, Elisa, Schmid, Hannes, Duerr-Stoerzer, Silke, Keppeler, Hildegard, Henes, Joerg Christoph, Klein, Reinhild, Hinterleitner, Clemens, Secker, Kathy-Ann, Schneidawind, Corina, Kanz, Lothar, Schneidawind, Dominik
Publicado 2019

Evaluation of Inhibitory Antibodies against the Muscarinic Acetylcholine Receptor Type 3 in Patients with Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

por Wilde, Anne-Christin Beatrice, Greverath, Lena Maria, Steinhagen, Lara Marleen, de Chamorro, Nina Wald, Leicht, Elise, Fischer, Janett, Herta, Toni, Berg, Thomas, Preuss, Beate, Klein, Reinhild, Tacke, Frank, Müller, Tobias
Publicado 2022

Defibrotide for the Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 2 Pediatric Pat...

por Lang, Peter, Eichholz, Thomas, Bakchoul, Tamam, Streiter, Monika, Petrasch, Maurice, Bösmüller, Hans, Klein, Reinhild, Rabsteyn, Armin, Lang, Anne-Marie, Adams, Constantin, Klingel, Karin, Gessner, Michaela, Rosenberger, Peter, Ruef, Peter, Handgretinger, Rupert
Publicado 2020

Increased soluble HLA in COVID-19 present a disease-related, diverse immunopeptidome associated with T cell immunity

por Nelde, Annika, Rieth, Jonas, Roerden, Malte, Dubbelaar, Marissa L., Hoenisch Gravel, Naomi, Bauer, Jens, Klein, Reinhild, Hoheisel, Tobias, Mahrhofer, Hartmut, Göpel, Siri, Bitzer, Michael, Hörber, Sebastian, Peter, Andreas, Heitmann, Jonas S., Walz, Juliane S.
Publicado 2022

Designing a SARS-CoV-2 T-Cell-Inducing Vaccine for High-Risk Patient Groups

por Rammensee, Hans-Georg, Gouttefangeas, Cécile, Heidu, Sonja, Klein, Reinhild, Preuß, Beate, Walz, Juliane Sarah, Nelde, Annika, Haen, Sebastian P., Reth, Michael, Yang, Jianying, Tabatabai, Ghazaleh, Bösmüller, Hans, Hoffmann, Helen, Schindler, Michael, Planz, Oliver, Wiesmüller, Karl-Heinz, Löffler, Markus W.
Publicado 2021

Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

por Gaißler, Andrea, Meldgaard, Trine Sundebo, Heeke, Christina, Babaei, Sepideh, Tvingsholm, Siri Amanda, Bochem, Jonas, Spreuer, Janine, Amaral, Teresa, Wagner, Nikolaus Benjamin, Klein, Reinhild, Meier, Friedegund, Garbe, Claus, Eigentler, Thomas K., Pawelec, Graham, Claassen, Manfred, Weide, Benjamin, Hadrup, Sine Reker, Wistuba-Hamprecht, Kilian
Publicado 2022

TOF(IMS) mass spectrometry-based immunopeptidomics refines tumor antigen identification

por Hoenisch Gravel, Naomi, Nelde, Annika, Bauer, Jens, Mühlenbruch, Lena, Schroeder, Sarah M., Neidert, Marian C., Scheid, Jonas, Lemke, Steffen, Dubbelaar, Marissa L., Wacker, Marcel, Dengler, Anna, Klein, Reinhild, Mauz, Paul-Stefan, Löwenheim, Hubert, Hauri-Hohl, Mathias, Martin, Roland, Hennenlotter, Jörg, Stenzl, Arnulf, Heitmann, Jonas S., Salih, Helmut R., Rammensee, Hans-Georg, Walz, Juliane S.
Publicado 2023

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial

por Fischer, M. Dominik, Michalakis, Stylianos, Wilhelm, Barbara, Zobor, Ditta, Muehlfriedel, Regine, Kohl, Susanne, Weisschuh, Nicole, Ochakovski, G. Alex, Klein, Reinhild, Schoen, Christian, Sothilingam, Vithiyanjali, Garcia-Garrido, Marina, Kuehlewein, Laura, Kahle, Nadine, Werner, Annette, Dauletbekov, Daniyar, Paquet-Durand, François, Tsang, Stephen, Martus, Peter, Peters, Tobias, Seeliger, Mathias, Bartz-Schmidt, Karl Ulrich, Ueffing, Marius, Zrenner, Eberhart, Biel, Martin, Wissinger, Bernd
Publicado 2020