Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

por Kraiger, Markus, Klein-Rodewald, Tanja, Rathkolb, Birgit, Calzada-Wack, Julia, Sanz-Moreno, Adrián, Fuchs, Helmut, Wolf, Eckhard, Gailus-Durner, Valérie, de Angelis, Martin Hrabě
Publicado 2022

New C3H Kit(N824K/WT) cancer mouse model develops late-onset malignant mammary tumors with high penetrance

por Klein-Rodewald, Tanja, Micklich, Kateryna, Sanz-Moreno, Adrián, Tost, Monica, Calzada-Wack, Julia, Adler, Thure, Klaften, Matthias, Sabrautzki, Sibylle, Aigner, Bernhard, Kraiger, Markus, Gailus-Durner, Valerie, Fuchs, Helmut, Gründer, Albert, Pahl, Heike, Wolf, Eckhard, Hrabe de Angelis, Martin, Rathkolb, Birgit
Publicado 2022

Knockout mouse models as a resource for the study of rare diseases

por da Silva-Buttkus, Patricia, Spielmann, Nadine, Klein-Rodewald, Tanja, Schütt, Christine, Aguilar-Pimentel, Antonio, Amarie, Oana V., Becker, Lore, Calzada-Wack, Julia, Garrett, Lillian, Gerlini, Raffaele, Kraiger, Markus, Leuchtenberger, Stefanie, Östereicher, Manuela A., Rathkolb, Birgit, Sanz-Moreno, Adrián, Stöger, Claudia, Hölter, Sabine M., Seisenberger, Claudia, Marschall, Susan, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin
Publicado 2023

RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure

por Jain, Mamta, Mann, Tomer D, Stulić, Maja, Rao, Shailaja P, Kirsch, Andrijana, Pullirsch, Dieter, Strobl, Xué, Rath, Claus, Reissig, Lukas, Moreth, Kristin, Klein‐Rodewald, Tanja, Bekeredjian, Raffi, Gailus‐Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Pablik, Eleonore, Cimatti, Laura, Martin, David, Zinnanti, Jelena, Graier, Wolfgang F, Sibilia, Maria, Frank, Saša, Levanon, Erez Y, Jantsch, Michael F
Publicado 2018

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency

por Treise, Irina, Huber, Eva M., Klein-Rodewald, Tanja, Heinemeyer, Wolfgang, Grassmann, Simon A., Basler, Michael, Adler, Thure, Rathkolb, Birgit, Helming, Laura, Andres, Christian, Klaften, Matthias, Landbrecht, Christina, Wieland, Thomas, Strom, Tim M., McCoy, Kathy D., Macpherson, Andrew J., Wolf, Eckhard, Groettrup, Marcus, Ollert, Markus, Neff, Frauke, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Groll, Michael, Busch, Dirk H.
Publicado 2018

A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse

por Biagosch, Caroline A., Vidali, Silvia, Faerberboeck, Michael, Hensler, Svenja-Viola, Becker, Lore, Amarie, Oana V., Aguilar-Pimentel, Antonio, Garrett, Lillian, Klein-Rodewald, Tanja, Rathkolb, Birgit, Zanuttigh, Enrica, Calzada-Wack, Julia, da Silva-Buttkus, Patricia, Rozman, Jan, Treise, Irina, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Janik, Dirk, Wurst, Wolfgang, Mayr, Johannes A., Klopstock, Thomas, Meitinger, Thomas, Prokisch, Holger, Iuso, Arcangela
Publicado 2021

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

por Müller-Eigner, Annika, Sanz-Moreno, Adrián, de-Diego, Irene, Venkatasubramani, Anuroop Venkateswaran, Langhammer, Martina, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Palma-Vera, Sergio, Gille, Benedikt, Forne, Ignasi, Imhof, Axel, Meng, Chen, Ludwig, Christina, Koch, Franziska, Heiker, John T., Kuhla, Angela, Caton, Vanessa, Brenmoehl, Julia, Reyer, Henry, Schoen, Jennifer, Fuchs, Helmut, Gailus-Durner, Valerie, Hoeflich, Andreas, de Angelis, Martin Hrabe, Peleg, Shahaf
Publicado 2022

METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth

por Ignatova, Valentina V., Kaiser, Steffen, Ho, Jessica Sook Yuin, Bing, Xinyang, Stolz, Paul, Tan, Ying Xim, Lee, Chee Leng, Gay, Florence Pik Hoon, Lastres, Palma Rico, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Sanz-Moreno, Adrián, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Ibragimov, Emil, Valenta, Magdalena, Lukauskas, Saulius, Pavesi, Andrea, Marschall, Susan, Leuchtenberger, Stefanie, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Bultmann, Sebastian, Rando, Oliver J., Guccione, Ernesto, Kellner, Stefanie M., Schneider, Robert
Publicado 2020

The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs

por Ignatova, Valentina V., Stolz, Paul, Kaiser, Steffen, Gustafsson, Tobias H., Lastres, Palma Rico, Sanz-Moreno, Adrián, Cho, Yi-Li, Amarie, Oana V., Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Marschall, Susan, Kraiger, Markus, Garrett, Lillian, Seisenberger, Claudia, Hölter, Sabine M., Borland, Kayla, Van De Logt, Erik, Jansen, Pascal W.T.C., Baltissen, Marijke P., Valenta, Magdalena, Vermeulen, Michiel, Wurst, Wolfgang, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Rando, Oliver J., Kellner, Stefanie M., Bultmann, Sebastian, Schneider, Robert
Publicado 2020

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

por Kollmus, Heike, Fuchs, Helmut, Lengger, Christoph, Haselimashhadi, Hamed, Bogue, Molly A., Östereicher, Manuela A., Horsch, Marion, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Beckers, Johannes, Calzada-Wack, Julia, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M., Klein-Rodewald, Tanja, Maier, Holger, Mayer-Kuckuk, Philipp, Miller, Gregor, Moreth, Kristin, Neff, Frauke, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk, Graw, Jochen, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Mason, Jeremy, Torres, Arturo, Balling, Rudi, Mehaan, Terry, Gailus-Durner, Valerie, Schughart, Klaus, Hrabě de Angelis, Martin
Publicado 2020

Characterising a homozygous two‐exon deletion in UQCRH: comparing human and mouse phenotypes

por Vidali, Silvia, Gerlini, Raffaele, Thompson, Kyle, Urquhart, Jill E, Meisterknecht, Jana, Aguilar‐Pimentel, Juan Antonio, Amarie, Oana V, Becker, Lore, Breen, Catherine, Calzada‐Wack, Julia, Chhabra, Nirav F, Cho, Yi‐Li, da Silva‐Buttkus, Patricia, Feichtinger, René G, Gampe, Kristine, Garrett, Lillian, Hoefig, Kai P, Hölter, Sabine M, Jameson, Elisabeth, Klein‐Rodewald, Tanja, Leuchtenberger, Stefanie, Marschall, Susan, Mayer‐Kuckuk, Philipp, Miller, Gregor, Oestereicher, Manuela A, Pfannes, Kristina, Rathkolb, Birgit, Rozman, Jan, Sanders, Charlotte, Spielmann, Nadine, Stoeger, Claudia, Szibor, Marten, Treise, Irina, Walter, John H, Wurst, Wolfgang, Mayr, Johannes A, Fuchs, Helmut, Gärtner, Ulrich, Wittig, Ilka, Taylor, Robert W, Newman, William G, Prokisch, Holger, Gailus‐Durner, Valerie, Hrabě de Angelis, Martin
Publicado 2021

Implication of FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT)

por Riedhammer, Korbinian M., Nguyen, Thanh-Minh T., Koşukcu, Can, Calzada-Wack, Julia, Li, Yong, Saygılı, Seha, Wimmers, Vera, Kim, Gwang-Jin, Chrysanthou, Marialena, Bakey, Zeineb, Kraiger, Markus, Sanz-Moreno, Adrián, Amarie, Oana V, Rathkolb, Birgit, Klein-Rodewald, Tanja, Garrett, Lillian, Hölter, Sabine M., Seisenberger, Claudia, Haug, Stefan, Marschall, Susan, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, Wuttke, Matthias, de Angelis, Martin Hrabe, Ćomić, Jasmina, Doğan, Özlem Akgün, Özlük, Yasemin, Taşdemir, Mehmet, Ağbaş, Ayşe, Canpolat, Nur, Ćalışkan, Salim, Weber, Ruthild, Bergmann, Carsten, Jeanpierre, Cecile, Saunier, Sophie, Lim, Tze Y., Hildebrandt, Friedhelm, Alhaddad, Bader, Wu, Kaman, Antony, Dinu, Matschkal, Julia, Schaaf, Christian, Renders, Lutz, Schmaderer, Christoph, Meitinger, Thomas, Heemann, Uwe, Köttgen, Anna, Arnold, Sebastian, Ozaltin, Fatih, Schmidts, Miriam, Hoefele, Julia
Publicado 2023

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

por Xie, Kan, Fuchs, Helmut, Scifo, Enzo, Liu, Dan, Aziz, Ahmad, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, da Silva-Buttkus, Patricia, Calzada-Wack, Julia, Cho, Yi-Li, Deng, Yushuang, Edwards, A. Cole, Garrett, Lillian, Georgopoulou, Christina, Gerlini, Raffaele, Hölter, Sabine M., Klein-Rodewald, Tanja, Kramer, Michael, Leuchtenberger, Stefanie, Lountzi, Dimitra, Mayer-Kuckuk, Phillip, Nover, Lena L., Oestereicher, Manuela A., Overkott, Clemens, Pearson, Brandon L., Rathkolb, Birgit, Rozman, Jan, Russ, Jenny, Schaaf, Kristina, Spielmann, Nadine, Sanz-Moreno, Adrián, Stoeger, Claudia, Treise, Irina, Bano, Daniele, Busch, Dirk H., Graw, Jochen, Klingenspor, Martin, Klopstock, Thomas, Mock, Beverly A., Salomoni, Paolo, Schmidt-Weber, Carsten, Weiergräber, Marco, Wolf, Eckhard, Wurst, Wolfgang, Gailus-Durner, Valérie, Breteler, Monique M. B., Hrabě de Angelis, Martin, Ehninger, Dan
Publicado 2022

Innovations in phenotyping of mouse models in the German Mouse Clinic

por Fuchs, Helmut, Gailus-Durner, Valérie, Neschen, Susanne, Adler, Thure, Afonso, Luciana Caminha, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Bohla, Alexander, Calzada-Wack, Julia, Cohrs, Christian, Dewert, Anna, Fridrich, Barbara, Garrett, Lillian, Glasl, Lisa, Götz, Alexander, Hans, Wolfgang, Hölter, Sabine M., Horsch, Marion, Hurt, Anja, Janas, Eva, Janik, Dirk, Kahle, Melanie, Kistler, Martin, Klein-Rodewald, Tanja, Lengger, Christoph, Ludwig, Tonia, Maier, Holger, Marschall, Susan, Micklich, Kateryna, Möller, Gabriele, Naton, Beatrix, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Räß, Michael, Rathkolb, Birgit, Rozman, Jan, Scheerer, Markus, Schiller, Evelyn, Schrewe, Anja, Steinkamp, Ralph, Stöger, Claudia, Sun, Minxuan, Szymczak, Wilfried, Treise, Irina, Vargas Panesso, Ingrid Liliana, Vernaleken, Alexandra M., Willershäuser, Monja, Wolff-Muscate, Annemarie, Zeh, Ramona, Adamski, Jerzy, Beckers, Johannes, Bekeredjian, Raffi, Busch, Dirk H., Eickelberg, Oliver, Favor, Jack, Graw, Jochen, Höfler, Heinz, Höschen, Christoph, Katus, Hugo, Klingenspor, Martin, Klopstock, Thomas, Neff, Frauke, Ollert, Markus, Schulz, Holger, Stöger, Tobias, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Zimmer, Andreas, Hrabě de Angelis, Martin
Publicado 2012

Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics

por de Angelis, Martin Hrabě, Nicholson, George, Selloum, Mohammed, White, Jacqui, Morgan, Hugh, Ramirez-Solis, Ramiro, Sorg, Tania, Wells, Sara, Fuchs, Helmut, Fray, Martin, Adams, David J, Adams, Niels C, Adler, Thure, Aguilar-Pimentel, Antonio, Ali-Hadji, Dalila, Amann, Gregory, André, Philippe, Atkins, Sarah, Auburtin, Aurelie, Ayadi, Abdel, Becker, Julien, Becker, Lore, Bedu, Elodie, Bekeredjian, Raffi, Birling, Marie-Christine, Blake, Andrew, Bottomley, Joanna, Bowl, Mike, Brault, Véronique, Busch, Dirk H, Bussell, James N, Calzada-Wack, Julia, Cater, Heather, Champy, Marie-France, Charles, Philippe, Chevalier, Claire, Chiani, Francesco, Codner, Gemma F, Combe, Roy, Cox, Roger, Dalloneau, Emilie, Dierich, André, Di Fenza, Armida, Doe, Brendan, Duchon, Arnaud, Eickelberg, Oliver, Esapa, Chris T, El Fertak, Lahcen, Feigel, Tanja, Emelyanova, Irina, Estabel, Jeanne, Favor, Jack, Flenniken, Ann, Gambadoro, Alessia, Garrett, Lilian, Gates, Hilary, Gerdin, Anna-Karin, Gkoutos, George, Greenaway, Simon, Glasl, Lisa, Goetz, Patrice, Da Cruz, Isabelle Goncalves, Götz, Alexander, Graw, Jochen, Guimond, Alain, Hans, Wolfgang, Hicks, Geoff, Hölter, Sabine M, Höfler, Heinz, Hancock, John M, Hoehndorf, Robert, Hough, Tertius, Houghton, Richard, Hurt, Anja, Ivandic, Boris, Jacobs, Hughes, Jacquot, Sylvie, Jones, Nora, Karp, Natasha A, Katus, Hugo A, Kitchen, Sharon, Klein-Rodewald, Tanja, Klingenspor, Martin, Klopstock, Thomas, Lalanne, Valerie, Leblanc, Sophie, Lengger, Christoph, le Marchand, Elise, Ludwig, Tonia, Lux, Aline, McKerlie, Colin, Maier, Holger, Mandel, Jean-Louis, Marschall, Susan, Mark, Manuel, Melvin, David G, Meziane, Hamid, Micklich, Kateryna, Mittelhauser, Christophe, Monassier, Laurent, Moulaert, David, Muller, Stéphanie, Naton, Beatrix, Neff, Frauke, Nolan, Patrick M, Nutter, Lauryl MJ, Ollert, Markus, Pavlovic, Guillaume, Pellegata, Natalia S, Peter, Emilie, Petit-Demoulière, Benoit, Pickard, Amanda, Podrini, Christine, Potter, Paul, Pouilly, Laurent, Puk, Oliver, Richardson, David, Rousseau, Stephane, Quintanilla-Fend, Leticia, Quwailid, Mohamed M, Racz, Ildiko, Rathkolb, Birgit, Riet, Fabrice, Rossant, Janet, Roux, Michel, Rozman, Jan, Ryder, Ed, Salisbury, Jennifer, Santos, Luis, Schäble, Karl-Heinz, Schiller, Evelyn, Schrewe, Anja, Schulz, Holger, Steinkamp, Ralf, Simon, Michelle, Stewart, Michelle, Stöger, Claudia, Stöger, Tobias, Sun, Minxuan, Sunter, David, Teboul, Lydia, Tilly, Isabelle, Tocchini-Valentini, Glauco P, Tost, Monica, Treise, Irina, Vasseur, Laurent, Velot, Emilie, Vogt-Weisenhorn, Daniela, Wagner, Christelle, Walling, Alison, Weber, Bruno, Wendling, Olivia, Westerberg, Henrik, Willershäuser, Monja, Wolf, Eckhard, Wolter, Anne, Wood, Joe, Wurst, Wolfgang, Yildirim, Ali Önder, Zeh, Ramona, Zimmer, Andreas, Zimprich, Annemarie, Holmes, Chris, Steel, Karen P, Herault, Yann, Gailus-Durner, Valérie, Mallon, Ann-Marie, Brown, Steve DM
Publicado 2015