Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex

por Pennington, Luke F., Gasser, Pascal, Kleinboelting, Silke, Zhang, Chensong, Skiniotis, Georgios, Eggel, Alexander, Jardetzky, Theodore S.
Publicado 2021

The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab

por Gasser, Pascal, Tarchevskaya, Svetlana S., Guntern, Pascal, Brigger, Daniel, Ruppli, Rahel, Zbären, Noemi, Kleinboelting, Silke, Heusser, Christoph, Jardetzky, Theodore S., Eggel, Alexander
Publicado 2020

Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase

por Ramos-Espiritu, Lavoisier, Kleinboelting, Silke, Navarrete, Felipe A., Alvau, Antonio, Visconti, Pablo E., Valsecchi, Federica, Starkov, Anatoly, Manfredi, Giovanni, Buck, Hannes, Adura, Carolina, Zippin, Jonathan H., van den Heuvel, Joop, Glickman, J. Fraser, Steegborn, Clemens, Levin, Lonny R., Buck, Jochen
Publicado 2016