Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Lepr(db)/J mouse model of non-alcoholic fatty liver disease (NAFLD...

por Su, Robin C., Lad, Apurva, Breidenbach, Joshua D., Blomquist, Thomas M., Gunning, William T., Dube, Prabhatchandra, Kleinhenz, Andrew L., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Publicado 2019

CD40 Receptor Knockout Protects against Microcystin-LR (MC-LR) Prolongation and Exacerbation of Dextran Sulfate Sodium (DSS)-Induced Colitis

por Su, Robin C., Warner, Emily A., Breidenbach, Joshua D., Lad, Apurva, Blomquist, Thomas M., Kleinhenz, Andrew L., Modyanov, Nikolai, Malhotra, Deepak, Kennedy, David J., Haller, Steven T.
Publicado 2020

Circulating Lactonase Activity but Not Protein Level of PON-1 Predicts Adverse Outcomes in Subjects with Chronic Kidney Disease

por Mohammed, Chrysan J., Xie, Yanmei, Brewster, Pamela S., Ghosh, Subhanwita, Dube, Prabhatchandra, Sarsour, Tiana, Kleinhenz, Andrew L., Crawford, Erin L., Malhotra, Deepak, James, Richard W., Kalra, Philip A., Haller, Steven T., Kennedy, David J.
Publicado 2019

Exposure to the Harmful Algal Bloom (HAB) Toxin Microcystin-LR (MC-LR) Prolongs and Increases Severity of Dextran Sulfate Sodium (DSS)-Induced Colitis

por Su, Robin C., Blomquist, Thomas M., Kleinhenz, Andrew L., Khalaf, Fatimah K., Dube, Prabhatchandra, Lad, Apurva, Breidenbach, Joshua D., Mohammed, Chrysan J., Zhang, Shungang, Baum, Caitlin E., Malhotra, Deepak, Kennedy, David J., Haller, Steven T.
Publicado 2019

Paraoxonase-1 Regulation of Renal Inflammation and Fibrosis in Chronic Kidney Disease

por Khalaf, Fatimah K., Mohammed, Chrysan J., Dube, Prabhatchandra, Connolly, Jacob A., Lad, Apurva, Ashraf, Usman M., Breidenbach, Joshua D., Su, Robin C., Kleinhenz, Andrew L., Malhotra, Deepak, Gohara, Amira F., Haller, Steven T., Kennedy, David J.
Publicado 2022

Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

por Zhang, Shungang, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra R., Mohammed, Chrysan J., Lad, Apurva, Stepkowski, Stanislaw, Hinds, Terry D., Kumarasamy, Sivarajan, Kleinhenz, Andrew, Tian, Jiang, Malhotra, Deepak, Kennedy, David J., Cooper, Christopher J., Haller, Steven T.
Publicado 2020

As We Drink and Breathe: Adverse Health Effects of Microcystins and Other Harmful Algal Bloom Toxins in the Liver, Gut, Lungs and Beyond

por Lad, Apurva, Breidenbach, Joshua D., Su, Robin C., Murray, Jordan, Kuang, Rebecca, Mascarenhas, Alison, Najjar, John, Patel, Shivani, Hegde, Prajwal, Youssef, Mirella, Breuler, Jason, Kleinhenz, Andrew L., Ault, Andrew P., Westrick, Judy A., Modyanov, Nikolai N., Kennedy, David J., Haller, Steven T.
Publicado 2022

Antioxidant Therapy Significantly Attenuates Hepatotoxicity following Low Dose Exposure to Microcystin-LR in a Murine Model of Diet-Induced Non-Alcoholic Fatty Liver Disease

por Lad, Apurva, Hunyadi, Jonathan, Connolly, Jacob, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra, Zhang, Shungang, Kleinhenz, Andrew L., Baliu-Rodriguez, David, Isailovic, Dragan, Hinds, Terry D., Gatto-Weis, Cara, Stanoszek, Lauren M., Blomquist, Thomas M., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Publicado 2022

Cardioprotective Role for Paraoxonase-1 in Chronic Kidney Disease

por Dube, Prabhatchandra, Khalaf, Fatimah K., DeRiso, Armelle, Mohammed, Chrysan J., Connolly, Jacob A., Battepati, Dhanushya, Lad, Apurva, Breidenbach, Joshua D., Kleinhenz, Andrew L., Khatib-Shahidi, Bella, Patel, Mitra, Tassavvor, Iman, Gohara, Amira F., Malhotra, Deepak, Morgan, Eric E., Haller, Steven T., Kennedy, David J.
Publicado 2022

Novel Model of Oxalate Diet-Induced Chronic Kidney Disease in Dahl-Salt-Sensitive Rats

por Dube, Prabhatchandra, Aradhyula, Vaishnavi, Lad, Apurva, Khalaf, Fatimah K., Breidenbach, Joshua D., Kashaboina, Eshita, Gorthi, Snigdha, Varatharajan, Shangari, Stevens, Travis W., Connolly, Jacob A., Soehnlen, Sophia M., Sood, Ambika, Marellapudi, Amulya, Ranabothu, Meghana, Kleinhenz, Andrew L., Domenig, Oliver, Dworkin, Lance D., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Publicado 2023

Chronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease

por Lad, Apurva, Su, Robin C., Breidenbach, Joshua D., Stemmer, Paul M., Carruthers, Nicholas J., Sanchez, Nayeli K., Khalaf, Fatimah K., Zhang, Shungang, Kleinhenz, Andrew L., Dube, Prabhatchandra, Mohammed, Chrysan J., Westrick, Judy A., Crawford, Erin L., Palagama, Dilrukshika, Baliu-Rodriguez, David, Isailovic, Dragan, Levison, Bruce, Modyanov, Nikolai, Gohara, Amira F., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Publicado 2019