Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease

por De, Suman, Klenerman, David
Publicado 2019

N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme

por Ye, Yu, Klenerman, David, Finley, Daniel
Publicado 2020

Single molecule imaging of protein aggregation in Dementia: Methods, insights and prospects

por Danial, John S.H., Klenerman, David
Publicado 2021

Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease

por Meisl, Georg, Knowles, Tuomas P. J., Klenerman, David
Publicado 2022

A Single gD Glycoprotein Can Mediate Infection by Herpes simplex Virus

por Clarke, Richard W., Drews, Anna, Browne, Helena, Klenerman, David
Publicado 2013

A hybrid scanning mode for fast scanning ion conductance microscopy (SICM) imaging

por Zhukov, Alex, Richards, Owen, Ostanin, Victor, Korchev, Yuri, Klenerman, David
Publicado 2012

Tau-Hsp70 interaction on the single molecule level

por Kundel, Franziska, Kjaergaard, Magnus, Shammas, Sarah, Jackson, Sophie, Klenerman, David
Publicado 2013

Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever

por Ponjavic, Aleks, Ye, Yu, Laue, Ernest, Lee, Steven F., Klenerman, David
Publicado 2018

Contact-Free Scanning and Imaging with the Scanning Ion Conductance Microscope

por Del Linz, Samantha, Willman, Eero, Caldwell, Matthew, Klenerman, David, Fernández, Anibal, Moss, Guy
Publicado 2014

Monitoring Ca(2+) elevations in individual astrocytes upon local release of amyloid beta in acute brain slices

por Tyurikova, Olga, Zheng, Kaiyu, Rings, Annika, Drews, Anna, Klenerman, David, Rusakov, Dmitri A.
Publicado 2018

Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme

por Cliffe, Rachel, Sang, Jason C., Kundel, Franziska, Finley, Daniel, Klenerman, David, Ye, Yu
Publicado 2019

Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

por Sang, Jason C., Hidari, Eric, Meisl, Georg, Ranasinghe, Rohan T., Spillantini, Maria Grazia, Klenerman, David
Publicado 2021

Endocytic pathways: combined scanning ion conductance and surface confocal microscopy study

por Shevchuk, Andrew I., Hobson, Phil, Lab, Max J., Klenerman, David, Krauzewicz, Nina, Korchev, Yuri E.
Publicado 2008

A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging()

por Bell, Laurence, Seshia, Ashwin, Lando, David, Laue, Ernest, Palayret, Matthieu, Lee, Steven F., Klenerman, David
Publicado 2014

Lipid peroxidation is essential for α‐synuclein‐induced cell death

por Angelova, Plamena R., Horrocks, Mathew H., Klenerman, David, Gandhi, Sonia, Abramov, Andrey Y., Shchepinov, Mikhail S.
Publicado 2015

Alpha Synuclein only Forms Fibrils In Vitro when Larger than its Critical Size of 70 Monomers

por Sanchez, Santiago Enrique, Whiten, Daniel R., Meisl, Georg, Ruggeri, Francesco Simone, Hidari, Eric, Klenerman, David
Publicado 2021

Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States

por Latty, Sarah L., Felce, James H., Weimann, Laura, Lee, Steven F., Davis, Simon J., Klenerman, David
Publicado 2015

Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution

por Taylor, Christopher G., Meisl, Georg, Horrocks, Mathew H., Zetterberg, Henrik, Knowles, Tuomas P. J., Klenerman, David
Publicado 2018

Single-Molecule Analysis of the Human Telomerase RNA·Dyskerin Interaction and the Effect of Dyskeratosis Congenita Mutations

por Ashbridge, Beth, Orte, Angel, Yeoman, Justin A., Kirwan, Michael, Vulliamy, Tom, Dokal, Inderjeet, Klenerman, David, Balasubramanian, Shankar
Publicado 2009

Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

por Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
Publicado 2013