Following Ariadne's thread: a new perspective on RBR ubiquitin ligases

por Wenzel, Dawn M, Klevit, Rachel E
Publicado 2012

Modulation of Ca(V)1.2 Channels by Mg(2+) Acting at an EF-hand Motif in the COOH-terminal Domain

por Brunet, Sylvain, Scheuer, Todd, Klevit, Rachel, Catterall, William A.
Publicado 2005

A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers

por Delbecq, Scott P., Rosenbaum, Joel C., Klevit, Rachel E.
Publicado 2015

UbcH7 reactivity profile reveals Parkin and HHARI to be RING/HECT hybrids

por Wenzel, Dawn M., Lissounov, Alexei, Brzovic, Peter S., Klevit, Rachel E.
Publicado 2011

E2 enzymes: more than just middle men

por Stewart, Mikaela D, Ritterhoff, Tobias, Klevit, Rachel E, Brzovic, Peter S
Publicado 2016

Indirect sexual selection drives rapid sperm protein evolution in abalone

por Wilburn, Damien Beau, Tuttle, Lisa M, Klevit, Rachel E, Swanson, Willie J
Publicado 2019

The Ubiquitin-Conjugating Enzyme, UbcM2, Is Restricted to Monoubiquitylation by a Two-Fold Mechanism That Involves Backside Residues of E2 and Lys48 of Ubiquitin

por Nguyen, Linda, Plafker, Kendra S., Starnes, Andrew, Cook, Matt, Klevit, Rachel E., Plafker, Scott M.
Publicado 2014

Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin

por Woods, Christopher N., Ulmer, Lindsey D., Guttman, Miklos, Bush, Matthew F., Klevit, Rachel E.
Publicado 2023

Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

por Clouser, Amanda F, Baughman, Hannah ER, Basanta, Benjamin, Guttman, Miklos, Nath, Abhinav, Klevit, Rachel E
Publicado 2019

Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4

por Tuttle, Lisa M., Pacheco, Derek, Warfield, Linda, Wilburn, Damien B., Hahn, Steven, Klevit, Rachel E.
Publicado 2021

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

por Tuttle, Lisa M., Pacheco, Derek, Warfield, Linda, Luo, Jie, Ranish, Jeff, Hahn, Steven, Klevit, Rachel E.
Publicado 2018

Cbl interacts with multiple E2s in vitro and in cells

por Liyasova, Mariya S., Ma, Ke, Voeller, Donna, Ryan, Philip E., Chen, Jinqiu, Klevit, Rachel E., Lipkowitz, Stanley
Publicado 2019

Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly‐ubiquitylation

por Lips, Christian, Ritterhoff, Tobias, Weber, Annika, Janowska, Maria K, Mustroph, Mandy, Sommer, Thomas, Klevit, Rachel E
Publicado 2020

Allosteric Activation of the RNF146 Ubiquitin Ligase by a Poly(ADP-ribosyl)ation Signal

por DaRosa, Paul A., Wang, Zhizhi, Jiang, Xiaomo, Pruneda, Jonathan N., Cong, Feng, Klevit, Rachel E., Xu, Wenqing
Publicado 2014

A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis

por Rajagopal, Ponni, Tse, Eric, Borst, Andrew J, Delbecq, Scott P, Shi, Lei, Southworth, Daniel R, Klevit, Rachel E
Publicado 2015

Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans

por Thapa, Ishor, Vahrenkamp, Russell, Witus, Samuel R, Lightle, Caitlin, Falkenberg, Owen, Sellin Jeffries, Marlo K, Klevit, Rachel E, Stewart, Mikaela D
Publicado 2022

Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination

por Puvar, Kedar, Iyer, Shalini, Fu, Jiaqi, Kenny, Sebastian, Negrón Terón, Kristos I., Luo, Zhao-Qing, Brzovic, Peter S., Klevit, Rachel E., Das, Chittaranjan
Publicado 2020

A native chemical chaperone in the human eye lens

por Serebryany, Eugene, Chowdhury, Sourav, Woods, Christopher N, Thorn, David C, Watson, Nicki E, McClelland, Arthur A, Klevit, Rachel E, Shakhnovich, Eugene I
Publicado 2022

The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector

por Akturk, Anil, Wasilko, David J., Wu, Xiaochun, Liu, Yao, Zhang, Yong, Qiu, Jiazhang, Luo, Zhao-Qing, Reiter, Katherine H., Brzovic, Peter S., Klevit, Rachel E., Mao, Yuxin
Publicado 2018

Infantile onset spinocerebellar ataxia caused by compound heterozygosity for Twinkle mutations and modeling of Twinkle mutations causing recessive disease

por Pierce, Sarah B., Gulsuner, Suleyman, Stapleton, Gail A., Walsh, Tom, Lee, Ming K., Mandell, Jessica B., Morales, Augusto, Klevit, Rachel E., King, Mary-Claire, Rogers, R. Curtis
Publicado 2016