Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE

por Cauwels, Anje, Van Lint, Sandra, Rogge, Elke, Verhee, Annick, Van Den Eeckhout, Bram, Pang, Shengru, Prinz, Marco, Kley, Niko, Uzé, Gilles, Tavernier, Jan
Publicado 2021

Specific targeting of IL-1β activity to CD8(+) T cells allows for safe use as a vaccine adjuvant

por Van Den Eeckhout, Bram, Van Hoecke, Lien, Burg, Elianne, Van Lint, Sandra, Peelman, Frank, Kley, Niko, Uzé, Gilles, Saelens, Xavier, Tavernier, Jan, Gerlo, Sarah
Publicado 2020

Selective IL-1 activity on CD8(+) T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication

por Van Den Eeckhout, Bram, Huyghe, Leander, Van Lint, Sandra, Burg, Elianne, Plaisance, Stéphane, Peelman, Frank, Cauwels, Anje, Uzé, Gilles, Kley, Niko, Gerlo, Sarah, Tavernier, Jan
Publicado 2021

Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies

por Huyghe, Leander, Van Parys, Alexander, Cauwels, Anje, Van Lint, Sandra, De Munter, Stijn, Bultinck, Jennyfer, Zabeau, Lennart, Hostens, Jeroen, Goethals, An, Vanderroost, Nele, Verhee, Annick, Uzé, Gilles, Kley, Niko, Peelman, Frank, Vandekerckhove, Bart, Brouckaert, Peter, Tavernier, Jan
Publicado 2020

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

por Van Lint, Sandra, Van Parys, Alexander, Van Den Eeckhout, Bram, Vandamme, Niels, Plaisance, Stephane, Verhee, Annick, Catteeuw, Dominiek, Rogge, Elke, De Geest, Jennifer, Vanderroost, Nele, Roels, Jana, Saeys, Yvan, Uzé, Gilles, Kley, Niko, Cauwels, Anje, Tavernier, Jan
Publicado 2023