Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism

por Soldano, Anabel, Klinke, Sebastián, Otero, Lisandro H., Rivera, Mario, Catalano-Dupuy, Daniela L., Ceccarelli, Eduardo A.
Publicado 2017

Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state

por Rinaldi, Jimena, Fernández, Ignacio, Poth, Lucía M., Shepard, William E., Savko, Martin, Goldbaum, Fernando A., Klinke, Sebastián
Publicado 2018

Engineering a bifunctional copper site in the cupredoxin fold by loop-directed mutagenesis

por Espinoza-Cara, Andrés, Zitare, Ulises, Alvarez-Paggi, Damián, Klinke, Sebastián, Otero, Lisandro H., Murgida, Daniel H., Vila, Alejandro J.
Publicado 2018

A Highly Conserved Iron-Sulfur Cluster Assembly Machinery between Humans and Amoeba Dictyostelium discoideum: The Characterization of Frataxin

por Olmos, Justo, Pignataro, María Florencia, Benítez dos Santos, Ana Belén, Bringas, Mauro, Klinke, Sebastián, Kamenetzky, Laura, Velazquez, Francisco, Santos, Javier
Publicado 2020

An Atypical Riboflavin Pathway Is Essential for Brucella abortus Virulence

por Bonomi, Hernán Ruy, Marchesini, María Inés, Klinke, Sebastián, Ugalde, Juan E., Zylberman, Vanesa, Ugalde, Rodolfo A., Comerci, Diego J., Goldbaum, Fernando Alberto
Publicado 2010

Asymmetric bifunctional protein nanoparticles through redesign of self-assembly

por Sosa, Santiago, Rossi, Andrés H., Szalai, Alan M., Klinke, Sebastián, Rinaldi, Jimena, Farias, Ana, Berguer, Paula M., Nadra, Alejandro D., Stefani, Fernando D., Goldbaum, Fernando A., Bonomi, Hernán R.
Publicado 2019

Draft Genome Sequence of Methylobacterium sp. Strain V23, Isolated from Accretion Ice of the Antarctic Subglacial Lake Vostok

por Sapp, Amanda, Huguet-Tapia, José C., Sánchez-Lamas, Maximiliano, Antelo, Giuliano T., Primo, Emiliano D., Rinaldi, Jimena, Klinke, Sebastián, Goldbaum, Fernando A., Bonomi, Hernán R., Christner, Brent C., Otero, Lisandro H.
Publicado 2018

A disordered region retains the full protease inhibitor activity and the capacity to induce CD8(+) T cells in vivo of the oral vaccine adjuvant U-Omp19

por Laura Darriba, M., Castro, Celeste Pueblas, Coria, Lorena M., Bruno, Laura, Laura Cerutti, M., Otero, Lisandro H., Chemes, Lucía B., Rasia, Rodolfo M., Klinke, Sebastián, Cassataro, Juliana, Pasquevich, Karina A.
Publicado 2022

Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase

por Rinaldi, Jimena, Fernández, Ignacio, Shin, Heewhan, Sycz, Gabriela, Gunawardana, Semini, Kumarapperuma, Indika, Paz, Juan M., Otero, Lisandro H., Cerutti, María L., Zorreguieta, Ángeles, Ren, Zhong, Klinke, Sebastián, Yang, Xiaojing, Goldbaum, Fernando A.
Publicado 2021

Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif

por Lorenzo, Ramiro, Defelipe, Lucas A., Aliperti, Lucio, Niebling, Stephan, Custódio, Tânia F., Löw, Christian, Schwarz, Jennifer J., Remans, Kim, Craig, Patricio O., Otero, Lisandro H., Klinke, Sebastián, García-Alai, María, Sánchez, Ignacio E., Alonso, Leonardo G.
Publicado 2021

Development of high-affinity nanobodies specific for Na(V)1.4 and Na(V)1.5 voltage-gated sodium channel isoforms

por Srinivasan, Lakshmi, Alzogaray, Vanina, Selvakumar, Dakshnamurthy, Nathan, Sara, Yoder, Jesse B., Wright, Katharine M., Klinke, Sebastián, Nwafor, Justin N., Labanda, María S., Goldbaum, Fernando A., Schön, Arne, Freire, Ernesto, Tomaselli, Gordon F., Amzel, L. Mario, Ben-Johny, Manu, Gabelli, Sandra B.
Publicado 2022

Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level

por Otero, Lisandro H., Foscaldi, Sabrina, Antelo, Giuliano T., Rosano, Germán L., Sirigu, Serena, Klinke, Sebastián, Defelipe, Lucas A., Sánchez-Lamas, Maximiliano, Battocchio, Giovanni, Conforte, Valeria, Vojnov, Adrián A., Chavas, Leonard M. G., Goldbaum, Fernando A., Mroginski, Maria-Andrea, Rinaldi, Jimena, Bonomi, Hernán R.
Publicado 2021

A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers

por Llauger, Gabriela, Melero, Roberto, Monti, Demián, Sycz, Gabriela, Huck-Iriart, Cristián, Cerutti, María L., Klinke, Sebastián, Mikkelsen, Evelyn, Tijman, Ariel, Arranz, Rocío, Alfonso, Victoria, Arellano, Sofía M., Goldbaum, Fernando A., Sterckx, Yann G. J., Carazo, José-María, Kaufman, Sergio B., Dans, Pablo D., del Vas, Mariana, Otero, Lisandro H.
Publicado 2023

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein*

por Sacerdoti, Mariana, Gross, Lissy Z.F., Riley, Andrew M., Zehnder, Karin, Ghode, Abhijeet, Klinke, Sebastián, Anand, Ganesh Srinivasan, Paris, Kristina, Winkel, Angelika, Herbrand, Amanda, Godage, H. Yasmin, Cozier, Gyles E., Süß, Evelyn, Schulze, Jörg O., Pastor-Flores, Daniel, Bollini, Mariela, Cappellari, María Victoria, Svergun, Dmitri, Gräwert, Melissa A., Aramendia, Pedro F., Leroux, Alejandro E., Potter, Barry V.L., Camacho, Carlos J., Biondi, Ricardo M.
Publicado 2023