DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells

por Zhao, Fei, Kim, Wootae, Kloeber, Jake A., Lou, Zhenkun
Publicado 2020

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization

por Yan, Yuanliang, Xu, Zhijie, Huang, Jinzhou, Guo, Guijie, Gao, Ming, Kim, Wootae, Zeng, Xiangyu, Kloeber, Jake A, Zhu, Qian, Zhao, Fei, Luo, Kuntian, Lou, Zhenkun
Publicado 2020

m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis

por Gao, Ming, Qi, Zijuan, Feng, Wenya, Huang, Hongyang, Xu, Zhijie, Dong, Zheng, Xu, Ming, Han, Jinxiang, Kloeber, Jake A., Huang, Jinzhou, Lou, Zhenkun, Liu, Sijin
Publicado 2022

USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP

por Gao, Ming, Guo, Guijie, Huang, Jinzhou, Kloeber, Jake A., Zhao, Fei, Deng, Min, Tu, Xinyi, Kim, Wootae, Zhou, Qin, Zhang, Chao, Yin, Ping, Luo, Kuntian, Lou, Zhenkun
Publicado 2020

LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination‐mediated DNA double strand break repair

por Chen, Lifeng, Hou, Jing, Zeng, Xiangyu, Guo, Qiang, Deng, Min, Kloeber, Jake A, Tu, Xinyi, Zhao, Fei, Wu, Zheming, Huang, Jinzhou, Luo, Kuntian, Kim, Wootae, Lou, Zhenkun
Publicado 2021

RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination

por Zhu, Qian, Huang, Jinzhou, Huang, Hongyang, Li, Huan, Yi, Peiqiang, Kloeber, Jake A., Yuan, Jian, Chen, Yuping, Deng, Min, Luo, Kuntian, Gao, Ming, Guo, Guijie, Tu, Xinyi, Yin, Ping, Zhang, Yong, Su, Jun, Chen, Jiayi, Lou, Zhenkun
Publicado 2021

Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

por Frede, Julia, Anand, Praveen, Sotudeh, Noori, Pinto, Ricardo A., Nair, Monica S., Stuart, Hannah, Yee, Andrew J., Vijaykumar, Tushara, Waldschmidt, Johannes M., Potdar, Sayalee, Kloeber, Jake A., Kokkalis, Antonis, Dimitrova, Valeriya, Mann, Mason, Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.
Publicado 2021

Cell-free DNA for the detection of emerging treatment failure in relapsed/refractory multiple myeloma

por Waldschmidt, Johannes M., Yee, Andrew J., Vijaykumar, Tushara, Pinto Rengifo, Ricardo A., Frede, Julia, Anand, Praveen, Bianchi, Giada, Guo, Guangwu, Potdar, Sayalee, Seifer, Charles, Nair, Monica S., Kokkalis, Antonis, Kloeber, Jake A., Shapiro, Samantha, Budano, Lillian, Mann, Mason, Friedman, Robb, Lipe, Brea, Campagnaro, Erica, O’Donnell, Elizabeth K., Zhang, Cheng-Zhong, Laubach, Jacob P., Munshi, Nikhil C., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.
Publicado 2022