Molecular Profiling of Thyroid Nodules: Current Role for the Afirma Gene Expression Classifier on Clinical Decision Making

por Kloos, Richard T.
Publicado 2017

A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology

por Kloos, Richard T., Monroe, Robert J., Traweek, S. Thomas, Lanman, Richard B., Kennedy, Giulia C.
Publicado 2016

Analytical Verification Performance of Afirma Genomic Sequencing Classifier in the Diagnosis of Cytologically Indeterminate Thyroid Nodules

por Hao, Yangyang, Choi, Yoonha, Babiarz, Joshua E., Kloos, Richard T., Kennedy, Giulia C., Huang, Jing, Walsh, P. Sean
Publicado 2019

THU680 Cytologic And Molecular Assessment Of Isthmus Thyroid Nodules

por Jasim, Sina, Chen, Yang, Jiang, Rouchen, Hao, Yangyang, Huang, Jing, Klopper, Joshua P, Kloos, Richard T, Brown, Taylor C
Publicado 2023

Extending expressed RNA genomics from surgical decision making for cytologically indeterminate thyroid nodules to targeting therapies for metastatic thyroid cancer

por Ali, Syed Z., Siperstein, Allan, Sadow, Peter M., Golding, Allan C., Kennedy, Giulia C., Kloos, Richard T., Ladenson, Paul W.
Publicado 2019

Maximizing Small Biopsy Patient Samples: Unified RNA-Seq Platform Assessment of over 120,000 Patient Biopsies

por Walsh, P. Sean, Hao, Yangyang, Ding, Jie, Qu, Jianghan, Wilde, Jonathan, Jiang, Ruochen, Kloos, Richard T., Huang, Jing, Kennedy, Giulia C.
Publicado 2022

Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules

por Goldner, Whitney S., Angell, Trevor E., McAdoo, Sallie Lou, Babiarz, Joshua, Sadow, Peter M., Nabhan, Fadi A., Nasr, Christian, Kloos, Richard T.
Publicado 2019

The Afirma Xpression Atlas for thyroid nodules and thyroid cancer metastases: Insights to inform clinical decision‐making from a fine‐needle aspiration sample

por Krane, Jeffrey F., Cibas, Edmund S., Endo, Mayumi, Marqusee, Ellen, Hu, Mimi I., Nasr, Christian E., Waguespack, Steven G., Wirth, Lori J., Kloos, Richard T.
Publicado 2020

Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer

por Ni, Ying, Seballos, Spencer, Ganapathi, Shireen, Gurin, Danielle, Fletcher, Benjamin, Ngeow, Joanne, Nagy, Rebecca, Kloos, Richard T, Ringel, Matthew D, LaFramboise, Thomas, Eng, Charis
Publicado 2015

SAT630 Analytical Validation Of A Telomerase Reverse Transcriptase (TERT) Promoter Mutation Assay

por Iyer, Priyanka, Dadu, Ramona, Barque, Anna, Cleslei, Zanelli, Jiang, Huimin, Walsh, Sean, Zheng, Xingyu, Hao, Yangyang, Huang, Jing, Klopper, Joshua P, Kloos, Richard T, Cabanillas, Maria
Publicado 2023

OR32-03 mRNA Expression Based Tumor Behavior Prediction Models In Thyroid Nodules

por Golding, Allan, Correa, Gabriel, Sheker, Evana Valenzuela, Jiang, Rouchen, Hao, Yangyang, Liu, Yang, Huang, Jing, Klopper, Joshua P, Kloos, Richard T, Kennedy, Giulia C, Bimston, David
Publicado 2023

MON-LB097 The Genomic Landscape of Preoperative FNAs Positive for the Afirma GSC Medullary Thyroid Cancer Classifier

por Waguespack, Steven, Busaidy, Naifa, Hu, Mimi, Grubbs, Elizabeth, Weitzman, Steven, Wirth, Lori, Zafereo, Mark, Babiarz, Joshua, Hao, Yangyang, Huang, Jing, Kennedy, Giulia, Walsh, P. Sean, Kloos, Richard
Publicado 2019

MON-LB88 Positive Predictive Value of TP53 Variants in Bethesda III/IV Thyroid Fine-Needle Aspirates

por Livhits, Masha J, Hu, Mimi I, Waguespack, Steven G, Wirth, Lori J, Ladenson, Paul W, Stack, Brendan C, Hao, Yangyang, Babiarz, Joshua E, Kennedy, Giulia C, Kloos, Richard T
Publicado 2020

Identification of Hürthle cell cancers: solving a clinical challenge with genomic sequencing and a trio of machine learning algorithms

por Hao, Yangyang, Duh, Quan-Yang, Kloos, Richard T., Babiarz, Joshua, Harrell, R. Mack, Traweek, S. Thomas, Kim, Su Yeon, Fedorowicz, Grazyna, Walsh, P. Sean, Sadow, Peter M., Huang, Jing, Kennedy, Giulia C.
Publicado 2019

OR28-04 Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates

por Wirth, Lori J, Grubbs, Elizabeth G, Livhits, Masha J, Sherman, Steven I, Weitzman, Steven P, Dosiou, Chrysoula, Ladenson, Paul W, Hao, Yangyang, Babiarz, Joshua E, Kennedy, Giulia C, Kloos, Richard T
Publicado 2020

Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations

por Whitmer, Dorota, Phay, John E., Holt, Shelby, O’Donnell, Benjamin, Nguyen, Jay, Joseph, Dennis, Chi, Anthony, Wu, Shuyang, Hao, Yangyang, Huang, Jing, Klopper, Joshua P., Kloos, Richard T., Kennedy, Giulia C., Shin, Joyce
Publicado 2022

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes

por Pagan, Moraima, Kloos, Richard T., Lin, Chu-Fang, Travers, Kevin J., Matsuzaki, Hajime, Tom, Ed Y., Kim, Su Yeon, Wong, Mei G., Stewart, Andrew C., Huang, Jing, Walsh, P. Sean, Monroe, Robert J., Kennedy, Giulia C.
Publicado 2016

Analytical and Clinical Validation of Expressed Variants and Fusions From the Whole Transcriptome of Thyroid FNA Samples

por Angell, Trevor E., Wirth, Lori J., Cabanillas, Maria E., Shindo, Maisie L., Cibas, Edmund S., Babiarz, Joshua E., Hao, Yangyang, Kim, Su Yeon, Walsh, P. Sean, Huang, Jing, Kloos, Richard T., Kennedy, Giulia C., Waguespack, Steven G.
Publicado 2019

LBSAT255 Real World Performance Of The Afirma Genomic Sequencing Classifier (GSC) - A Meta-analysis

por Nasr, Christian E, Andriol, Massimiliano, Endo, Mayumi, Mack Harrell, R, Livhits, Masha J, Osakwe, Ibitoro, Polavarapu, Preethi, Wei, Shuanzeng, Zheng, Xingyu, Jiang, Ruochen, Hao, Yangyang, Huang, JIng, Kloppe, Joshua P, Kloos, Richard T, Kennedy, Giulia, Angell, Trevor E
Publicado 2022

Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)—A Meta-analysis

por Nasr, Christian E, Andrioli, Massimiliano, Endo, Mayumi, Harrell, R Mack, Livhits, Masha J, Osakwe, Ibitoro, Polavarapu, Preethi, Siperstein, Allan, Wei, Shuanzeng, Zheng, Xingyu, Jiang, Ruochen, Hao, Yangyang, Huang, J I ng, Klopper, Joshua P, Kloos, Richard T, Kennedy, Giulia, Angell, Trevor E
Publicado 2022