Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe

por Gastl, Bastian, Klotz-Noack, Kathleen, Klinger, Bertram, Ispasanie, Sylvia, Salib, Krenoula Hani Fouad, Zuber, Johannes, Mamlouk, Soulafa, Bublitz, Natalie, Blüthgen, Nils, Horst, David, Morkel, Markus, Schäfer, Reinhold, Sers, Christine
Publicado 2020

Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer

por Uhlitz, Florian, Bischoff, Philip, Peidli, Stefan, Sieber, Anja, Trinks, Alexandra, Lüthen, Mareen, Obermayer, Benedikt, Blanc, Eric, Ruchiy, Yana, Sell, Thomas, Mamlouk, Soulafa, Arsie, Roberto, Wei, Tzu‐Ting, Klotz‐Noack, Kathleen, Schwarz, Roland F, Sawitzki, Birgit, Kamphues, Carsten, Beule, Dieter, Landthaler, Markus, Sers, Christine, Horst, David, Blüthgen, Nils, Morkel, Markus
Publicado 2021

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

por Ozkan-Dagliyan, Irem, Diehl, J. Nathaniel, George, Samuel D., Schaefer, Antje, Papke, Bjoern, Klotz-Noack, Kathleen, Waters, Andrew M., Goodwin, Craig M., Gautam, Prson, Pierobon, Mariaelena, Peng, Sen, Gilbert, Thomas S.K., Lin, Kevin H., Dagliyan, Onur, Wennerberg, Krister, Petricoin, Emanuel F., Tran, Nhan L., Bhagwat, Shripad V., Tiu, Ramon V., Peng, Sheng-Bin, Herring, Laura E., Graves, Lee M., Sers, Christine, Wood, Kris C., Cox, Adrienne D., Der, Channing J.
Publicado 2020