ACTH Receptor (MC2R) Specificity: What Do We Know About Underlying Molecular Mechanisms?

por Fridmanis, Davids, Roga, Ance, Klovins, Janis
Publicado 2017

The Association of Common SNPs and Haplotypes in CETP Gene with HDL Cholesterol Levels in Latvian Population

por Radovica, Ilze, Fridmanis, Davids, Vaivade, Iveta, Nikitina-Zake, Liene, Klovins, Janis
Publicado 2013

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

por Kalnina, Ineta, Kapa, Ivo, Pirags, Valdis, Ignatovica, Vita, Schiöth, Helgi B, Klovins, Janis
Publicado 2009

Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

por Zake, Darta Maija, Kurlovics, Janis, Zaharenko, Linda, Komasilovs, Vitalijs, Klovins, Janis, Stalidzans, Egils
Publicado 2021

Metformin Transport Rates Between Plasma and Red Blood Cells in Humans

por Kurlovics, Janis, Zake, Darta Maija, Zaharenko, Linda, Berzins, Kristaps, Klovins, Janis, Stalidzans, Egils
Publicado 2021

Genome Database of the Latvian Population (LGDB): Design, Goals, and Primary Results

por Rovite, Vita, Wolff-Sagi, Yael, Zaharenko, Linda, Nikitina-Zake, Liene, Grens, Elmars, Klovins, Janis
Publicado 2018

Variations in the Relative Abundance of Gut Bacteria Correlate with Lipid Profiles in Healthy Adults

por Kalnina, Ineta, Gudra, Dita, Silamikelis, Ivars, Viksne, Kristine, Roga, Ance, Skinderskis, Edmunds, Fridmanis, Davids, Klovins, Janis
Publicado 2023

Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes

por Silamiķele, Laila, Silamiķelis, Ivars, Ustinova, Monta, Kalniņa, Zane, Elbere, Ilze, Petrovska, Ramona, Kalniņa, Ineta, Kloviņš, Jānis
Publicado 2021

Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance

por Brīvība, Monta, Silamiķele, Laila, Kalniņa, Ineta, Silamiķelis, Ivars, Birzniece, Līga, Ansone, Laura, Jagare, Lauma, Elbere, Ilze, Kloviņš, Jānis
Publicado 2023

Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

por Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Publicado 2020

Spatial variation of the gut microbiome in response to long-term metformin treatment in high-fat diet-induced type 2 diabetes mouse model of both sexes

por Silamiķele, Laila, Saksis, Rihards, Silamiķelis, Ivars, Kotoviča, Patrīcija Paulīne, Brīvība, Monta, Kalniņa, Ineta, Kalniņa, Zane, Fridmanis, Dāvids, Kloviņš, Jānis
Publicado 2023

Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL–C levels in a latvian population

por Radovica-Spalvina, Ilze, Latkovskis, Gustavs, Silamikelis, Ivars, Fridmanis, Davids, Elbere, Ilze, Ventins, Karlis, Ozola, Guna, Erglis, Andrejs, Klovins, Janis
Publicado 2015

The Correlation Between Abnormal Uterine Artery Flow in the First Trimester and Genetic Thrombophilic Alteration: A Prospective Case-Controlled Pilot Study

por Vedmedovska, Natalija, Bokucava, Diana, Kivite-Urtane, Anda, Rovite, Vita, Zake-Nikitina, Liene, Klovins, Janis, Fodina, Violeta, Donders, Gilbert G. G.
Publicado 2020

Case Report: Micro-RNAs in Plasma From Bilateral Inferior Petrosal Sinus Sampling and Peripheral Blood From Corticotroph Pituitary Neuroendocrine Tumors

por Niedra, Helvijs, Peculis, Raitis, Konrade, Ilze, Balcere, Inga, Romanovs, Mihails, Steina, Liva, Stukens, Janis, Sokolovska, Jelizaveta, Klovins, Janis, Rovite, Vita
Publicado 2022

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

por Haitina, Tatjana, Klovins, Janis, Takahashi, Akiyoshi, Löwgren, Maja, Ringholm, Aneta, Enberg, Johan, Kawauchi, Hiroshi, Larson, Earl T, Fredriksson, Robert, Schiöth, Helgi B
Publicado 2007

Functional Characteristics of Multipotent Mesenchymal Stromal Cells from Pituitary Adenomas

por Megnis, Kaspars, Mandrika, Ilona, Petrovska, Ramona, Stukens, Janis, Rovite, Vita, Balcere, Inga, Jansone, Laima Sabine, Peculis, Raitis, Pirags, Valdis, Klovins, Janis
Publicado 2016

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

por Ciganoka, Darja, Balcere, Inga, Kapa, Ivo, Peculis, Raitis, Valtere, Andra, Nikitina-Zake, Liene, Lase, Ieva, Schiöth, Helgi B, Pirags, Valdis, Klovins, Janis
Publicado 2011

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

por Ustinova, Monta, Peculis, Raitis, Rescenko, Raimonds, Rovite, Vita, Zaharenko, Linda, Elbere, Ilze, Silamikele, Laila, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Publicado 2021

Whole exome sequencing reveals novel risk genes of pituitary neuroendocrine tumors

por Peculis, Raitis, Rovite, Vita, Megnis, Kaspars, Balcere, Inga, Breiksa, Austra, Nazarovs, Jurijs, Stukens, Janis, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Publicado 2022

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

por Elbere, Ilze, Kalnina, Ineta, Silamikelis, Ivars, Konrade, Ilze, Zaharenko, Linda, Sekace, Kristine, Radovica-Spalvina, Ilze, Fridmanis, Davids, Gudra, Dita, Pirags, Valdis, Klovins, Janis
Publicado 2018