Identification of Compounds for Butyrylcholinesterase Inhibition

por Li, Shuaizhang, Li, Andrew J., Travers, Jameson, Xu, Tuan, Sakamuru, Srilatha, Klumpp-Thomas, Carleen, Huang, Ruili, Xia, Menghang
Publicado 2021

Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4

por Cheff, Dorian M., Cheng, Qing, Guo, Hui, Travers, Jameson, Klumpp-Thomas, Carleen, Shen, Min, Arnér, Elias S.J., Hall, Matthew D.
Publicado 2023

Effect of D614G Spike Variant on Immunoglobulin G, M, or A Spike Seroassay Performance

por Klumpp-Thomas, Carleen, Kalish, Heather, Hicks, Jennifer, Mehalko, Jennifer, Drew, Matthew, Memoli, Matthew J, Hall, Matthew D, Esposito, Dominic, Sadtler, Kaitlyn
Publicado 2020

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

por Zhu, Wei, Xu, Miao, Chen, Catherine Z., Guo, Hui, Shen, Min, Hu, Xin, Shinn, Paul, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei
Publicado 2020

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

por Zhu, Wei, Xu, Miao, Chen, Catherine Z., Guo, Hui, Shen, Min, Hu, Xin, Shinn, Paul, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei
Publicado 2020

Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

por Ooka, Masato, Zhao, Jinghua, Shah, Pranav, Travers, Jameson, Klumpp-Thomas, Carleen, Xu, Xin, Huang, Ruili, Ferguson, Stephen, Witt, Kristine L., Smith-Roe, Stephanie L., Simeonov, Anton, Xia, Menghang
Publicado 2022

Quantitative Chemotherapeutic Profiling of Gynecologic Cancer Cell Lines Using Approved Drugs and Bioactive Compounds()

por Gorshkov, Kirill, Sima, Ni, Sun, Wei, Lu, Billy, Huang, Wei, Travers, Jameson, Klumpp-Thomas, Carleen, Michael, Samuel G., Xu, Tuan, Huang, Ruili, Lee, Emily M., Cheng, Xiaodong, Zheng, Wei
Publicado 2018

TRLS-04. PRECLINICAL VALIDATION OF A NOVEL THERAPEUTIC STRATEGY FOR CHOROID PLEXUS CARCINOMA

por Martin, Brice, Garman, Tyler, Laramee, Madeline, Wang, Amy, Zhang, Xiaohu, Beck, Erin, Wilson, Kelli, Klumpp-thomas, Carleen, Mcknight, Crystal, Xu, Xin, Hagen, Natalie, Holland, David, Thomas, Craig, Thomas, Nadia, Souweidane, Mark
Publicado 2023

Serologic cross-reactivity of SARS-CoV-2 with endemic and seasonal Betacoronaviruses

por Hicks, Jennifer, Klumpp-Thomas, Carleen, Kalish, Heather, Shunmugavel, Anandakumar, Mehalko, Jennifer, Denson, John-Paul, Snead, Kelly, Drew, Matthew, Corbett, Kizzmekia, Graham, Barney, Hall, Matthew D, Memoli, Matthew J, Esposito, Dominic, Sadtler, Kaitlyn
Publicado 2020

Serologic Cross-Reactivity of SARS-CoV-2 with Endemic and Seasonal Betacoronaviruses

por Hicks, Jennifer, Klumpp-Thomas, Carleen, Kalish, Heather, Shunmugavel, Anandakumar, Mehalko, Jennifer, Denson, John-Paul, Snead, Kelly R., Drew, Matthew, Corbett, Kizzmekia S., Graham, Barney S., Hall, Matthew D., Memoli, Matthew J., Esposito, Dominic, Sadtler, Kaitlyn
Publicado 2021

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

por Breglio, Kimberly F., Amato, Roberto, Eastman, Richard, Lim, Pharath, Sa, Juliana M., Guha, Rajarshi, Ganesan, Sundar, Dorward, David W., Klumpp-Thomas, Carleen, McKnight, Crystal, Fairhurst, Rick M., Roberts, David, Thomas, Craig, Simon, Anna Katharina
Publicado 2018

mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening

por Chen, Lu, Wilson, Kelli, Goldlust, Ian, Mott, Bryan T., Eastman, Richard, Davis, Mindy I., Zhang, Xiaohu, McKnight, Crystal, Klumpp-Thomas, Carleen, Shinn, Paul, Simmons, John, Gormally, Mike, Michael, Sam, Thomas, Craig J., Ferrer, Marc, Guha, Rajarshi
Publicado 2016

Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles

por Chen, Catherine Z., Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Straus, Marco R., Zhu, Wei, Shinn, Paul, Guo, Hui, Shen, Min, Klumpp-Thomas, Carleen, Michael, Samuel G., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R.
Publicado 2020

mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer

por Kumari, Anju, Gesumaria, Lisa, Liu, Yan-Jin, Hughitt, V. Keith, Zhang, Xiaohu, Ceribelli, Michele, Wilson, Kelli M., Klumpp-Thomas, Carleen, Chen, Lu, McKnight, Crystal, Itkin, Zina, Thomas, Craig J., Mock, Beverly A., Schrump, David S., Chen, Haobin
Publicado 2023

ATRT-11. DEVELOPMENT OF NOVEL PRECLINICAL MODELS AND THERAPEUTIC STRATEGIES FOR ETMR

por Cocito, Carolina, Arias-Stella, Esteban Uceda, Zhang, Xiaohu, McKnight, Crystal, Itkin, Zina, Klumpp-Thomas, Carleen, Cruzeiro, Gustavo Alencastro Veiga, Chi, Susan N, Pisapia, David J, Filbin, Mariella G, Dahmane, Nadia, Thomas, Craig J, Greenfield, Jeffrey P
Publicado 2023

Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition

por Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Travers, Jameson, Klumpp-Thomas, Carleen, Yu, Wenbo, MacKerell, Alexander D., Sakamuru, Srilatha, Ooka, Masato, Xue, Fengtian, Sipes, Nisha S., Hsieh, Jui-Hua, Ryan, Kristen, Simeonov, Anton, Santillo, Michael F., Xia, Menghang
Publicado 2021

A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

por Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Shen, Min, Guo, Hui, Zhu, Wei, Klumpp-Thomas, Carleen, Michael, Sam, Itkin, Misha, Itkin, Zina, Straus, Marco R., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R., Chen, Catherine Z.
Publicado 2021

A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

por Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Shen, Min, Guo, Hui, Zhu, Wei, Klumpp-Thomas, Carleen, Michael, Sam, Itkin, Misha, Itkin, Zina, Straus, Marco R., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R., Chen, Catherine Z.
Publicado 2022

A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase

por Martinez, Natalia J., Asawa, Rosita R., Cyr, Matthew G., Zakharov, Alexey, Urban, Daniel J., Roth, Jacob S., Wallgren, Eric, Klumpp-Thomas, Carleen, Coussens, Nathan P., Rai, Ganesha, Yang, Shyh-Ming, Hall, Matthew D., Marugan, Juan J., Simeonov, Anton, Henderson, Mark J.
Publicado 2018

A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

por Shrimp, Jonathan H., Janiszewski, John, Chen, Catherine Z., Xu, Miao, Wilson, Kelli M., Kales, Stephen C., Sanderson, Philip E., Shinn, Paul, Itkin, Zina, Guo, Hui, Shen, Min, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei, Simeonov, Anton, Hall, Matthew D.
Publicado 2022