Naturally-Occurring Canine Invasive Urothelial Carcinoma: A Model for Emerging Therapies

por Sommer, Breann C., Dhawan, Deepika, Ratliff, Timothy L., Knapp, Deborah W.
Publicado 2018

Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer

por Dhawan, Deepika, Hahn, Noah M., Ramos-Vara, José A., Knapp, Deborah W.
Publicado 2018

Naturally Occurring Canine Invasive Urinary Bladder Cancer: A Complementary Animal Model to Improve the Success Rate in Human Clinical Trials of New Cancer Drugs

por Fulkerson, Christopher M., Dhawan, Deepika, Ratliff, Timothy L., Hahn, Noah M., Knapp, Deborah W.
Publicado 2017

Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model

por Chand, Damini, Dhawan, Deepika, Sankin, Alexander, Ren, Xiaoxin, Lin, Juan, Schoenberg, Mark, Knapp, Deborah W., Zang, Xingxing
Publicado 2019

An ultrasound based platform for image-guided radiotherapy in canine bladder cancer patients

por Sick, Justin T., Rancilio, Nicholas J., Fulkerson, Caroline V., Plantenga, Jeannie M., Knapp, Deborah W., Stantz, Keith M.
Publicado 2019

The miRNome of canine invasive urothelial carcinoma

por Varvil, Mara S., Bailey, Taylor, Dhawan, Deepika, Knapp, Deborah W., Ramos-Vara, José A., dos Santos, Andrea P.
Publicado 2022

A Nonselective Cyclooxygenase Inhibitor Enhances the Activity of Vinblastine in a Naturally-Occurring Canine Model of Invasive Urothelial Carcinoma

por Knapp, Deborah W., Ruple-Czerniak, Audrey, Ramos-Vara, José A., Naughton, James F., Fulkerson, Christopher M., Honkisz, Sonia I.
Publicado 2016

Fatty Acid Patterns Detected By Ambient Ionization Mass Spectrometry in Canine Invasive Urothelial Carcinoma From Dogs of Different Breeds

por D’Hue, Cedric A., Dhawan, Deepika, Peat, Tyler, Ramos-Vara, José, Jarmusch, Alan, Knapp, Deborah W., Cooks, R. Graham
Publicado 2018

In vitro effect of chlorambucil on human glioma cell lines (SF767 and U87-MG), and human microvascular endothelial cell (HMVEC) and endothelial progenitor cells (ECFCs), in the con...

por Reese, Michael J., Knapp, Deborah W., Anderson, Kimberly M., Mund, Julie A., Case, Jamie, Jones, David R., Packer, Rebecca A.
Publicado 2018

RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

por Parker, Heidi G., Dhawan, Deepika, Harris, Alex C., Ramos-Vara, Jose A., Davis, Brian W., Knapp, Deborah W., Ostrander, Elaine A.
Publicado 2020

cTULIP: application of a human-based RNA-seq primary tumor classification tool for cross-species primary tumor classification in canine

por Long, Jiaxin, Ganakammal, Satishkumar Ranganathan, Jones, Sara E., Kothandaraman, Harish, Dhawan, Deepika, Ogas, Joe, Knapp, Deborah W., Beyers, Matthew, Lanman, Nadia A.
Publicado 2023

Multicomponent, peptide-targeted glycol chitosan nanoparticles containing ferrimagnetic iron oxide nanocubes for bladder cancer multimodal imaging

por Key, Jaehong, Dhawan, Deepika, Cooper, Christy L, Knapp, Deborah W, Kim, Kwangmeyung, Kwon, Ick Chan, Choi, Kuiwon, Park, Kinam, Decuzzi, Paolo, Leary, James F
Publicado 2016

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer

por Dhawan, Deepika, Paoloni, Melissa, Shukradas, Shweta, Choudhury, Dipanwita Roy, Craig, Bruce A., Ramos-Vara, José A., Hahn, Noah, Bonney, Patty L., Khanna, Chand, Knapp, Deborah W.
Publicado 2015

Naturally-Occurring Invasive Urothelial Carcinoma in Dogs, a Unique Model to Drive Advances in Managing Muscle Invasive Bladder Cancer in Humans

por Knapp, Deborah W., Dhawan, Deepika, Ramos-Vara, José A., Ratliff, Timothy L., Cresswell, Gregory M., Utturkar, Sagar, Sommer, Breann C., Fulkerson, Christopher M., Hahn, Noah M.
Publicado 2020

Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody

por Nagaya, Tadanobu, Okuyama, Shuhei, Ogata, Fusa, Maruoka, Yasuhiro, Knapp, Deborah W., Karagiannis, Sophia N., Fazekas-Singer, Judit, Choyke, Peter L., LeBlanc, Amy K., Jensen-Jarolim, Erika, Kobayashi, Hisataka
Publicado 2018

Development of an Anti-canine PD-L1 Antibody and Caninized PD-L1 Mouse Model as Translational Research Tools for the Study of Immunotherapy in Humans

por Oh, Wonkyung, Kim, Alyssa Min Jung, Dhawan, Deepika, Kirkham, Perry M., Ostafe, Raluca, Franco, Jackeline, Aryal, Uma K., Carnahan, Robert H., Patsekin, Valery, Robinson, J. Paul, Knapp, Deborah W., Lim, Seung-Oe
Publicado 2023

Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma

por Szigetvari, Nicholas M., Dhawan, Deepika, Ramos-Vara, José A., Leamon, Christopher P., Klein, Patrick J., Ruple, A. Audrey, Heng, Hock Gan, Pugh, Michael R., Rao, Satish, Vlahov, Iontcho R., Deshuillers, Pierre L., Low, Philip S., Fourez, Lindsey M., Cournoyer, Ashleigh M., Knapp, Deborah W.
Publicado 2018

Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma

por Dhawan, Deepika, Ramos-Vara, José A., Utturkar, Sagar M., Ruple, Audrey, Tersey, Sarah A., Nelson, Jennifer B., Cooper, Bruce R., Heng, Hock Gan, Ostrander, Elaine A., Parker, Heidi G., Hahn, Noah M., Adams, Larry G., Fulkerson, Christopher M., Childress, Michael O., Bonney, Patty L., Royce, Christine, Fourez, Lindsey M., Enstrom, Alexander W., Ambrosius, Lisbeth A., Knapp, Deborah W.
Publicado 2022