Opiate Drugs with Abuse Liability Hijack the Endogenous Opioid System to Disrupt Neuronal and Glial Maturation in the Central Nervous System

por Hauser, Kurt F., Knapp, Pamela E.
Publicado 2018

HIV-1 Tat Inhibits Autotaxin Lysophospholipase D Activity and Modulates Oligodendrocyte Differentiation

por Wheeler, Natalie A., Fuss, Babette, Knapp, Pamela E., Zou, ShiPing
Publicado 2016

Morphine Enhances HIV-1(SF162)-Mediated Neuron Death and Delays Recovery of Injured Neurites

por Masvekar, Ruturaj R., El-Hage, Nazira, Hauser, Kurt F., Knapp, Pamela E.
Publicado 2014

Opiate Drug Use and the Pathophysiology of NeuroAIDS

por Hauser, Kurt F, Fitting, Sylvia, Dever, Seth M, Podhaizer, Elizabeth M, Knapp, Pamela E
Publicado 2012

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

por Barbour, Aaron J., Nass, Sara R., Hahn, Yun K., Hauser, Kurt F., Knapp, Pamela E.
Publicado 2021

Neurodegeneration Within the Amygdala Is Differentially Induced by Opioid and HIV-1 Tat Exposure

por Nass, Sara R., Ohene-Nyako, Michael, Hahn, Yun K., Knapp, Pamela E., Hauser, Kurt F.
Publicado 2022

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior

por Hahn, Yun Kyung, Podhaizer, Elizabeth M., Farris, Sean P., Miles, Michael F., Hauser, Kurt F., Knapp, Pamela E.
Publicado 2013

Cross-talk between microglia and neurons regulates HIV latency

por Alvarez-Carbonell, David, Ye, Fengchun, Ramanath, Nirmala, Garcia-Mesa, Yoelvis, Knapp, Pamela E., Hauser, Kurt F., Karn, Jonathan
Publicado 2019

Morphine Exacerbates HIV-1 Tat-Induced Cytokine Production in Astrocytes through Convergent Effects on [Ca(2+)](i), NF-κB Trafficking and Transcription

por El-Hage, Nazira, Bruce-Keller, Annadora J., Yakovleva, Tatiana, Bazov, Igor, Bakalkin, Georgy, Knapp, Pamela E., Hauser, Kurt F.
Publicado 2008

A central role for glial CCR5 in directing the neuropathological interactions of HIV-1 Tat and opiates

por Kim, Sarah, Hahn, Yun Kyung, Podhaizer, Elizabeth M, McLane, Virginia D, Zou, Shiping, Hauser, Kurt F, Knapp, Pamela E
Publicado 2018

Chronic HIV-1 Tat exposure alters anterior cingulate cortico-basal ganglia-thalamocortical synaptic circuitry, associated behavioral control, and immune regulation in male mice

por Nass, Sara R., Hahn, Yun K., McLane, Virginia D., Varshneya, Neil B., Damaj, M. Imad, Knapp, Pamela E., Hauser, Kurt F.
Publicado 2020

Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia

por Ohene-Nyako, Michael, Nass, Sara R., Richard, Hope T., Lukande, Robert, Nicol, Melanie R., McRae, MaryPeace, Knapp, Pamela E., Hauser, Kurt F.
Publicado 2023

Depressive-like Behavior Is Accompanied by Prefrontal Cortical Innate Immune Fatigue and Dendritic Spine Losses after HIV-1 Tat and Morphine Exposure

por Nass, Sara R., Hahn, Yun K., Ohene-Nyako, Michael, McLane, Virginia D., Damaj, M. Imad, Thacker, Leroy R., Knapp, Pamela E., Hauser, Kurt F.
Publicado 2023

Fractalkine/CX(3)CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death

por Suzuki, Masami, El-Hage, Nazira, Zou, Shiping, Hahn, Yun-Kyung, Sorrell, Mary E, Sturgill, Jamie L, Conrad, Daniel H, Knapp, Pamela E, Hauser, Kurt F
Publicado 2011

Reduced intraepidermal nerve fibre density, glial activation, and sensory changes in HIV type-1 Tat-expressing female mice: involvement of Tat during early stages of HIV-associated...

por Wodarski, Rachel, Bagdas, Deniz, Paris, Jason J., Pheby, Tim, Toma, Wisam, Xu, Ruqiang, Damaj, M. Imad, Knapp, Pamela E., Rice, Andrew S.C., Hauser, Kurt F.
Publicado 2018

Opiate Addiction Therapies and HIV-1 Tat: Interactive Effects on Glial [Ca(2+)]i, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity

por Fitting, Sylvia, Zou, Shiping, El-Hage1, Nazira, Suzuki, Masami, Paris, Jason J., Schier, Christina J., Rodríguez, José W., Rodriguez, Myosotys, Knapp, Pamela E., Hauser, Kurt F.
Publicado 2014

Pregnane steroidogenesis is altered by HIV-1 Tat and morphine: Physiological allopregnanolone is protective against neurotoxic and psychomotor effects

por Paris, Jason J., Liere, Philippe, Kim, Sarah, Mahdi, Fakhri, Buchanan, Meagan E., Nass, Sara R., Qrareya, Alaa N., Salahuddin, Mohammed F., Pianos, Antoine, Fernandez, Neïké, Shariat-Madar, Zia, Knapp, Pamela E., Schumacher, Michael, Hauser, Kurt F.
Publicado 2020

HIV-1 Tat and Morphine Differentially Disrupt Pyramidal Cell Structure and Function and Spatial Learning in Hippocampal Area CA1: Continuous versus Interrupted Morphine Exposure

por Marks, William D., Paris, Jason J., Barbour, Aaron J., Moon, Jean, Carpenter, Valerie J., McLane, Virginia D., Lark, Arianna R. S., Nass, Sara R., Zhang, Jingli, Yarotskyy, Viktor, McQuiston, A. Rory, Knapp, Pamela E., Hauser, Kurt F.
Publicado 2021

Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotec...

por Hermes, Douglas J., Jacobs, Ian R., Key, Megan C., League, Alexis F., Yadav-Samudrala, Barkha J., Xu, Changqing, McLane, Virginia D., Nass, Sara R., Jiang, Wei, Meeker, Rick B., Ignatowska-Jankowska, Bogna M., Lichtman, Aron H., Li, Zibo, Wu, Zhanhong, Yuan, Hong, Knapp, Pamela E., Hauser, Kurt F., Fitting, Sylvia
Publicado 2020