Knowledge of developmental pharmacology and modeling approaches should be used to avoid useless trials in children

por de Wildt, Saskia N., Knibbe, Catherijne A. J.
Publicado 2009

The Predictive Value of Glomerular Filtration Rate-Based Scaling of Pediatric Clearance and Doses for Drugs Eliminated by Glomerular Filtration with Varying Protein-Binding Propert...

por Cristea, Sinziana, Krekels, Elke H. J., Allegaert, Karel, Knibbe, Catherijne A. J.
Publicado 2020

Impact of Bariatric Surgery in the Short and Long Term: A Need for Time-Dependent Dosing of Drugs

por Lau, Cedric, van Kesteren, Charlotte, Smeenk, Robert, Huitema, Alwin, Knibbe, Catherijne A. J.
Publicado 2023

Comment on: "Preterm Physiologically Based Pharmacokinetic Model, Part I and Part II”

por Völler, Swantje, Flint, Robert B., Simons, Sinno H. P., Knibbe, Catherijne A. J.
Publicado 2021

Vancomycin Clearance in Obese Adults is not Predictive of Clearance in Obese Adolescents

por Zhang, Tan, Smit, Cornelis, Sherwin, Catherine M. T., Knibbe, Catherijne A. J., Krekels, Elke H. J.
Publicado 2023

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties

por Smit, Cornelis, Peeters, Mariska Y. M., van den Anker, John N., Knibbe, Catherijne A. J.
Publicado 2020

Dosing Recommendations for Vancomycin in Children and Adolescents with Varying Levels of Obesity and Renal Dysfunction: a Population Pharmacokinetic Study in 1892 Children Aged 1–1...

por Smit, Cornelis, Goulooze, Sebastiaan C., Brüggemann, Roger J. M., Sherwin, Catherine M., Knibbe, Catherijne A. J.
Publicado 2021

Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models

por Krekels, Elke H. J., van Hasselt, Johan G. C., Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A. J.
Publicado 2010

Predictors of Insulin Resistance in Children versus Adolescents with Obesity

por Lentferink, Yvette E., Elst, Marieke A. J., Knibbe, Catherijne A. J., van der Vorst, Marja M. J.
Publicado 2017

Children Are Not Small Adults, but Can We Treat Them As Such?

por Krekels, Elke H.J., Calvier, Elisa A.M., van der Graaf, Piet H., Knibbe, Catherijne A.J.
Publicado 2019

Towards Evidence-Based Weaning: a Mechanism-Based Pharmacometric Model to Characterize Iatrogenic Withdrawal Syndrome in Critically Ill Children

por Goulooze, Sebastiaan C., Ista, Erwin, van Dijk, Monique, Tibboel, Dick, Krekels, Elke H. J., Knibbe, Catherijne A. J.
Publicado 2021

The role of population PK–PD modelling in paediatric clinical research

por De Cock, Roosmarijn F. W., Piana, Chiara, Krekels, Elke H. J., Danhof, Meindert, Allegaert, Karel, Knibbe, Catherijne A. J.
Publicado 2010

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

por Mooij, Miriam G., Nies, Anne T., Knibbe, Catherijne A. J., Schaeffeler, Elke, Tibboel, Dick, Schwab, Matthias, de Wildt, Saskia N.
Publicado 2015

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method

por Calvier, E. A. M., Krekels, E. H. J., Johnson, T. N., Rostami-Hodjegan, A., Tibboel, D., Knibbe, Catherijne A. J.
Publicado 2019

Development and Stability Study of an Omeprazole Suppository for Infants

por Bestebreurtje, Petra, Roeleveld, Nel, Knibbe, Catherijne A. J., van Sorge, Adriaan A., Plötz, Frans B., de Wildt, Saskia N.
Publicado 2020

Pre- and Postnatal Maturation are Important for Fentanyl Exposure in Preterm and Term Newborns: A Pooled Population Pharmacokinetic Study

por Wu, Yunjiao, Völler, Swantje, Flint, Robert B., Simons, Sinno H. P., Allegaert, Karel, Fellman, Vineta, Knibbe, Catherijne A. J.
Publicado 2021

Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants

por Krekels, Elke H. J., van Ham, Saskia, Allegaert, Karel, de Hoon, Jan, Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A. J.
Publicado 2015

Asthma medication in children who are overweight/obese: justified treatment?

por Lentferink, Yvette E., Boogaart, Nienke E., Balemans, Walter A. F., Knibbe, Catherijne A. J., van der Vorst, Marja M. J.
Publicado 2019

Supervised Multidimensional Item Response Theory Modeling of Pediatric Iatrogenic Withdrawal Symptoms

por Goulooze, Sebastiaan C., Ista, Erwin, van Dijk, Monique, Hankemeier, Thomas, Tibboel, Dick, Knibbe, Catherijne A.J., Krekels, Elke H.J.
Publicado 2019

Pharmacokinetics and Pharmacodynamics of Posaconazole

por Chen, Lu, Krekels, Elke H. J., Verweij, Paul. E., Buil, Jochem B., Knibbe, Catherijne A. J., Brüggemann, Roger J. M.
Publicado 2020