USP8 Mutations in Pituitary Cushing Adenomas—Targeted Analysis by Next-Generation Sequencing

por Ballmann, Cora, Thiel, Anne, Korah, Hannah E, Reis, Anna-Carinna, Saeger, Wolfgang, Stepanow, Stefanie, Köhrer, Karl, Reifenberger, Guido, Knobbe-Thomsen, Christiane B, Knappe, Ulrich J, Scholl, Ute I
Publicado 2018

A sensitive and simple targeted proteomics approach to quantify transcription factor and membrane proteins of the unfolded protein response pathway in glioblastoma cells

por Nguyen, Chi D. L., Malchow, Sebastian, Reich, Stefan, Steltgens, Sascha, Shuvaev, Konstantin V., Loroch, Stefan, Lorenz, Christin, Sickmann, Albert, Knobbe-Thomsen, Christiane B., Tews, Björn, Medenbach, Jan, Ahrends, Robert
Publicado 2019

A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites

por Reich, Stefan, Nguyen, Chi D. L., Has, Canan, Steltgens, Sascha, Soni, Himanshu, Coman, Cristina, Freyberg, Moritz, Bichler, Anna, Seifert, Nicole, Conrad, Dominik, Knobbe-Thomsen, Christiane B., Tews, Björn, Toedt, Grischa, Ahrends, Robert, Medenbach, Jan
Publicado 2020

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

por Zuckermann, Marc, Hovestadt, Volker, Knobbe-Thomsen, Christiane B., Zapatka, Marc, Northcott, Paul A., Schramm, Kathrin, Belic, Jelena, Jones, David T. W., Tschida, Barbara, Moriarity, Branden, Largaespada, David, Roussel, Martine F., Korshunov, Andrey, Reifenberger, Guido, Pfister, Stefan M., Lichter, Peter, Kawauchi, Daisuke, Gronych, Jan
Publicado 2015

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

por Wirthschaft, Peter, Bode, Julia, Soni, Himanshu, Dietrich, Fabio, Krüwel, Thomas, Fischer, Bernd, Knobbe-Thomsen, Christiane B., Rossetti, Giulia, Hentschel, Andreas, Mack, Norman, Schönig, Kai, Breckwoldt, Michael O., Schmandke, André, Pusch, Stefan, Medenbach, Jan, Bendszus, Martin, Schwab, Martin E., von Deimling, Andreas, Kool, Marcel, Herold-Mende, Christel, Reifenberger, Guido, Ahrends, Robert, Tews, Björn
Publicado 2019

Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma

por Picard, Daniel, Felsberg, Jörg, Langini, Maike, Stachura, Paweł, Qin, Nan, Macas, Jadranka, Reiss, Yvonne, Bartl, Jasmin, Selt, Florian, Sigaud, Romain, Meyer, Frauke-D., Stefanski, Anja, Stühler, Kai, Roque, Lucia, Roque, Rafael, Pandyra, Aleksandra A., Brozou, Triantafyllia, Knobbe-Thomsen, Christiane, Plate, Karl H., Roesch, Alexander, Milde, Till, Reifenberger, Guido, Leprivier, Gabriel, Faria, Claudia C., Remke, Marc
Publicado 2023

The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma

por Ahmadov, Ulvi, Picard, Daniel, Bartl, Jasmin, Silginer, Manuela, Trajkovic-Arsic, Marija, Qin, Nan, Blümel, Lena, Wolter, Marietta, Lim, Jonathan K. M., Pauck, David, Winkelkotte, Alina Marie, Melcher, Marlen, Langini, Maike, Marquardt, Viktoria, Sander, Felix, Stefanski, Anja, Steltgens, Sascha, Hassiepen, Christina, Kaufhold, Anna, Meyer, Frauke-Dorothee, Seibt, Annette, Kleinesudeik, Lara, Hain, Anika, Münk, Carsten, Knobbe-Thomsen, Christiane Brigitte, Schramm, Alexander, Fischer, Ute, Leprivier, Gabriel, Stühler, Kai, Fulda, Simone, Siveke, Jens T., Distelmaier, Felix, Borkhardt, Arndt, Weller, Michael, Roth, Patrick, Reifenberger, Guido, Remke, Marc
Publicado 2021

Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti...

por Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Maue, Mara, Bartl, Jasmin, Ahmadov, Ulvi, Langini, Maike, Meyer, Frauke-Dorothee, Cole, Allison, Cruz-Cruz, Joselyn, Graef, Claus M, Wölfl, Matthias, Milde, Till, Witt, Olaf, Erdreich-Epstein, Anat, Leprivier, Gabriel, Kahlert, Ulf, Stefanski, Anja, Stühler, Kai, Keir, Stephen T, Bigner, Darell D, Hauer, Julia, Beez, Thomas, Knobbe-Thomsen, Christiane B, Fischer, Ute, Felsberg, Jörg, Hansen, Finn K, Vibhakar, Rajeev, Venkatraman, Sujatha, Cheshier, Samuel H, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Remke, Marc, Mitra, Siddhartha
Publicado 2023