CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies

por Knochelmann, Hannah M., Smith, Aubrey S., Dwyer, Connor J., Wyatt, Megan M., Mehrotra, Shikhar, Paulos, Chrystal M.
Publicado 2018

Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma

por Xiong, Ying, Neskey, David M., Horton, Joshua D., Paulos, Chrystal M., Knochelmann, Hannah M., Armeson, Kent E., Young, M. Rita I.
Publicado 2020

Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy

por Rangel Rivera, Guillermo O., Knochelmann, Hannah M., Dwyer, Connor J., Smith, Aubrey S., Wyatt, Megan M., Rivera-Reyes, Amalia M., Thaxton, Jessica E., Paulos, Chrystal M.
Publicado 2021

Case Report: Delayed Onset Multi-Organ Toxicities in a Melanoma Patient Achieving Complete Response to BRAF/MEK Inhibition

por Knochelmann, Hannah M., Ware, Michael Brandon, Rali, Aditya, Linderman, Susanne, Shantha, Jessica G., Lawson, David H., Yushak, Melinda, Swerlick, Robert, Paulos, Chrystal M., Yeh, Steven, Kudchadkar, Ragini
Publicado 2022

Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines

por Dwyer, Connor J., Knochelmann, Hannah M., Smith, Aubrey S., Wyatt, Megan M., Rangel Rivera, Guillermo O., Arhontoulis, Dimitrios C., Bartee, Eric, Li, Zihai, Rubinstein, Mark P., Paulos, Chrystal M.
Publicado 2019

The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020

por Yan, Flora, Knochelmann, Hannah M., Morgan, Patrick F., Kaczmar, John M., Neskey, David M., Graboyes, Evan M., Nguyen, Shaun A., Ogretmen, Besim, Sharma, Anand K., Day, Terry A.
Publicado 2020

Programmed death 1 (PD‐1) and ligand (PD‐L1) inhibitors in head and neck squamous cell carcinoma: A meta‐analysis

por Levy, Dylan A., Patel, Jaimin J., Nguyen, Shaun A., Nicholas Jungbauer, W., Neskey, David M., Cohen, Ezra E. W., Paulos, Chrystal M., Kaczmar, John A., Knochelmann, Hannah M., Day, Terry A.
Publicado 2022

Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8(+) T cells

por Dwyer, Connor J., Arhontoulis, Dimitrios C., Rangel Rivera, Guillermo O, Knochelmann, Hannah M., Smith, Aubrey S., Wyatt, Megan M., Rubinstein, Mark P., Atkinson, Carl, Thaxton, Jessica E., Neskey, David M., Paulos, Chrystal M.
Publicado 2020

B cells imprint adoptively transferred CD8(+) T cells with enhanced tumor immunity

por Smith, Aubrey S, Knochelmann, Hannah M, Wyatt, Megan M, Rangel Rivera, Guillermo O, Rivera-Reyes, Amalia M, Dwyer, Connor J, Ware, Michael B, Cole, Anna C, Neskey, David M, Rubinstein, Mark P, Liu, Bei, Thaxton, Jessica E, Bartee, Eric, Paulos, Chrystal M
Publicado 2022

Identification of human CD4(+) T cell populations with distinct antitumor activity

por Nelson, Michelle H., Knochelmann, Hannah M., Bailey, Stefanie R., Huff, Logan W., Bowers, Jacob S., Majchrzak-Kuligowska, Kinga, Wyatt, Megan M., Rubinstein, Mark P., Mehrotra, Shikhar, Nishimura, Michael I., Armeson, Kent E., Giresi, Paul G., Zilliox, Michael J., Broxmeyer, Hal E., Paulos, Chrystal M.
Publicado 2020

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

por Knochelmann, Hannah M, Rivera-Reyes, Amalia M, Wyatt, Megan M, Smith, Aubrey S, Chamness, Reilley, Dwyer, Connor J, Bobian, Michael, Rangel Rivera, Guillermo O, Horton, Joshuva D, Lilly, Michael, Romeo, Martin J, Timmers, Cynthia D, Rubinstein, Mark P, Neskey, David M, Paulos, Chrystal M
Publicado 2021

Response and recurrence correlates in individuals treated with neoadjuvant anti-PD-1 therapy for resectable oral cavity squamous cell carcinoma

por Liu, Sixue, Knochelmann, Hannah M., Lomeli, Shirley H., Hong, Aayoung, Richardson, Mary, Yang, Zhentao, Lim, Raymond J., Wang, Yan, Dumitras, Camelia, Krysan, Kostyantyn, Timmers, Cynthia, Romeo, Martin J., Krieg, Carsten, O’Quinn, Elizabeth C., Horton, Joshua D., Dubinett, Steve M., Paulos, Chrystal M., Neskey, David M., Lo, Roger S.
Publicado 2021

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner

por Ware, Michael Brandon, Phillips, Maggie, McQuinn, Christopher, Zaidi, Mohammad Y., Knochelmann, Hannah M., Greene, Emily, Robinson, Brian, Herting, Cameron J., Mace, Thomas A., Chen, Zhengjia, Zhang, Chao, Farren, Matthew R., Ruggieri, Amanda N., Bowers, Jacob S., Shakya, Reena, Farris, Alton B., Young, Gregory, Carson, William E., El-Rayes, Bassel, Paulos, Chrystal M., Lesinski, Gregory B.
Publicado 2023

Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma

por Knochelmann, Hannah M., Horton, Joshua D., Liu, Sixue, Armeson, Kent, Kaczmar, John M., Wyatt, Megan M., Richardson, Mary S., Lomeli, Shirley H., Xiong, Ying, Graboyes, Evan M., Lentsch, Eric J., Hornig, Joshua D., Skoner, Judith, Stalcup, Seth, Spampinato, Maria V., Garrett-Mayer, Elizabeth, O’Quinn, Elizabeth C., Timmers, Cynthia D., Romeo, Martin J., Wrangle, John M., Young, M. Rita I., Rubinstein, Mark P., Day, Terry A., Lo, Roger S., Paulos, Chrystal M., Neskey, David M.
Publicado 2021