Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

por Knoechel, Birgit, Lohr, Jens, Kahn, Estelle, Bluestone, Jeffrey A., Abbas, Abul K.
Publicado 2005

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

por Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.
Publicado 2006

Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma

por Mandelbaum, Joseph, Shestopalov, Ilya A., Henderson, Rachel E., Chau, Nicole G., Knoechel, Birgit, Wick, Michael J., Zon, Leonard I.
Publicado 2018

P324: CELL PLASTICITY PREDETERMINES TREATMENT RESPONSE IN T-ALL

por Dimitrova, Valeriya, Frede, Julia, Montanaro, Anna, Potdar, Sayalee, Stuart, Hannah, Sotoudeh, Noori, Van Scoyk, Alexandria, Bhatt, Shruti, Letai, Anthony, Aster, Jon, Lohr, Jens, Knoechel, Birgit
Publicado 2023

Peptidomimetic blockade of MYB in acute myeloid leukemia

por Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex
Publicado 2018

Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case

por Knoechel, Birgit, Bhatt, Ami, Pan, Li, Pedamallu, Chandra S., Severson, Eric, Gutierrez, Alejandro, Dorfman, David M., Kuo, Frank C., Kluk, Michael, Kung, Andrew L., Zweidler-McKay, Patrick, Meyerson, Matthew, Blacklow, Stephen C., DeAngelo, Daniel J., Aster, Jon C.
Publicado 2015

S188: CAR-T CELLS SHAPE THE IMMUNOLOGICAL POTENTIAL OF THE TUMOR MICROENVIRONMENT

por Frede, Julia, Poller, Julia, Shi, Kayleen, Stuart, Hannah, Sotoudeh, Noori, Lim, Klothilda, Wiggers, Caroline, Waldschmidt, Johannes, Dimitrova, Valeriya, Montanaro, Anna, Cho, Eugene, Vijaykumar, Tushara, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth, Martin, Nathan, Kaiser, Shari, Raab, Marc-Steffen, Knoechel, Birgit, Lohr, Jens
Publicado 2023

Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

por Frede, Julia, Anand, Praveen, Sotudeh, Noori, Pinto, Ricardo A., Nair, Monica S., Stuart, Hannah, Yee, Andrew J., Vijaykumar, Tushara, Waldschmidt, Johannes M., Potdar, Sayalee, Kloeber, Jake A., Kokkalis, Antonis, Dimitrova, Valeriya, Mann, Mason, Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.
Publicado 2021

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

por Drier, Yotam, Cotton, Matthew J., Williamson, Kaylyn E., Gillespie, Shawn M., Ryan, Russell J.H., Kluk, Michael J., Carey, Christopher D., Rodig, Scott J., Sholl, Lynette M, Afrogheh, Amir H., Faquin, William C., Queimado, Lurdes, Qi, Jun, Wick, Michael J., El-Naggar, Adel K., Bradner, James E., Moskaluk, Christopher A., Aster, Jon C., Knoechel, Birgit, Bernstein, Bradley E.
Publicado 2016

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

por Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, Roti, Giovanni
Publicado 2022

Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

por Li, Li, Mohanty, Vakul, Dou, Jinzhuang, Huang, Yuefan, Banerjee, Pinaki P., Miao, Qi, Lohr, Jens G., Vijaykumar, Tushara, Frede, Julia, Knoechel, Birgit, Muniz-Feliciano, Luis, Laskowski, Tamara J., Liang, Shaoheng, Moyes, Judy S., Nandivada, Vandana, Basar, Rafet, Kaplan, Mecit, Daher, May, Liu, Enli, Li, Ye, Acharya, Sunil, Lin, Paul, Shanley, Mayra, Rafei, Hind, Marin, David, Mielke, Stephan, Champlin, Richard E., Shpall, Elizabeth J., Chen, Ken, Rezvani, Katayoun
Publicado 2023

Cell-free DNA for the detection of emerging treatment failure in relapsed/refractory multiple myeloma

por Waldschmidt, Johannes M., Yee, Andrew J., Vijaykumar, Tushara, Pinto Rengifo, Ricardo A., Frede, Julia, Anand, Praveen, Bianchi, Giada, Guo, Guangwu, Potdar, Sayalee, Seifer, Charles, Nair, Monica S., Kokkalis, Antonis, Kloeber, Jake A., Shapiro, Samantha, Budano, Lillian, Mann, Mason, Friedman, Robb, Lipe, Brea, Campagnaro, Erica, O’Donnell, Elizabeth K., Zhang, Cheng-Zhong, Laubach, Jacob P., Munshi, Nikhil C., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.
Publicado 2022

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

por Ariës, Ingrid M., Bodaar, Kimberly, Karim, Salmaan A., Chonghaile, Triona Ni, Hinze, Laura, Burns, Melissa A., Pfirrmann, Maren, Degar, James, Landrigan, Jack T., Balbach, Sebastian, Peirs, Sofie, Menten, Björn, Isenhart, Randi, Stevenson, Kristen E., Neuberg, Donna S., Devidas, Meenakshi, Loh, Mignon L., Hunger, Stephen P., Teachey, David T., Rabin, Karen R., Winter, Stuart S., Dunsmore, Kimberly P., Wood, Brent L., Silverman, Lewis B., Sallan, Stephen E., Van Vlierberghe, Pieter, Orkin, Stuart H., Knoechel, Birgit, Letai, Anthony G., Gutierrez, Alejandro
Publicado 2018

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

por Kluk, Michael J., Ashworth, Todd, Wang, Hongfang, Knoechel, Birgit, Mason, Emily F., Morgan, Elizabeth A., Dorfman, David, Pinkus, Geraldine, Weigert, Oliver, Hornick, Jason L., Chirieac, Lucian R., Hirsch, Michelle, Oh, David J., South, Andrew P., Leigh, Irene M., Pourreyron, Celine, Cassidy, Andrew J., DeAngelo, Daniel J., Weinstock, David M., Krop, Ian E., Dillon, Deborah, Brock, Jane E., Lazar, Alexander J. F., Peto, Myron, Cho, Raymond J., Stoeck, Alexander, Haines, Brian B., Sathayanrayanan, Sriram, Rodig, Scott, Aster, Jon C.
Publicado 2013