Hypoxic regulation of osteoclast differentiation and bone resorption activity

por Knowles, Helen J
Publicado 2015

Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone

por Knowles, Helen J.
Publicado 2017

Multiple Roles of Angiopoietin-Like 4 in Osteolytic Disease

por Knowles, Helen J.
Publicado 2017

The Adenosine A(2B) Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments

por Knowles, Helen J.
Publicado 2019

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function

por Knowles, Helen J.
Publicado 2020

Hypoxia and oxidative stress in breast cancer: Hypoxia and tumourigenesis

por Knowles, Helen J, Harris, Adrian L
Publicado 2001

A New Method to Sort Differentiating Osteoclasts into Defined Homogeneous Subgroups

por Hulley, Philippa A., Knowles, Helen J.
Publicado 2022

Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts

por Morten, Karl J, Badder, Luned, Knowles, Helen J
Publicado 2013

Angiopoietin-Like 4 Is Over-Expressed in Rheumatoid Arthritis Patients: Association with Pathological Bone Resorption

por Swales, Catherine, Athanasou, Nicholas A., Knowles, Helen J.
Publicado 2014

Osteoblast–Osteoclast Coculture Amplifies Inhibitory Effects of FG‐4592 on Human Osteoclastogenesis and Reduces Bone Resorption

por Hulley, Philippa A, Papadimitriou‐Olivgeri, Ioanna, Knowles, Helen J
Publicado 2020

Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

por Knowles, Helen J, Schaefer, Karl-Ludwig, Dirksen, Uta, Athanasou, Nicholas A
Publicado 2010

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

por Knowles, Helen J., Cleton-Jansen, Anne-Marie, Korsching, Eberhard, Athanasou, Nicholas A.
Publicado 2010

Factors influencing variation in participation in the National Diabetes Audit and the impact on the Quality and Outcomes Framework indicators of diabetes care management

por Wright, Caroline E, Yeung, Stephen, Knowles, Helen, Woodhouse, Antoinette, Barron, Emma, Evans, Sian
Publicado 2018

Mature primary human osteocytes in mini organotypic cultures secrete FGF23 and PTH1-34-regulated sclerostin

por Knowles, Helen J., Chanalaris, Anastasios, Koutsikouni, Argyro, Cribbs, Adam P., Grover, Liam M., Hulley, Philippa A.
Publicado 2023

Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs

por Larrouture, Quitterie C., Cribbs, Adam P., Rao, Srinivasa R., Philpott, Martin, Snelling, Sarah J., Knowles, Helen J.
Publicado 2021

Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2

por Hulley, Philippa A, Bishop, Tammie, Vernet, Aude, Schneider, Jurgen E, Edwards, James R, Athanasou, Nick A, Knowles, Helen J
Publicado 2017

The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease

por Berghuis, Dagmar, Schilham, Marco W, Santos, Susy J, Savola, Suvi, Knowles, Helen J, Dirksen, Uta, Schaefer, Karl-Ludwig, Vakkila, Jukka, Hogendoorn, Pancras CW, Lankester, Arjan C
Publicado 2012

Does laryngeal reinnervation or type I thyroplasty give better voice results for patients with unilateral vocal fold paralysis (VOCALIST): study protocol for a feasibility randomis...

por Blackshaw, Helen, Carding, Paul, Jepson, Marcus, Mat Baki, Marina, Ambler, Gareth, Schilder, Anne, Morris, Stephen, Degun, Aneeka, Yu, Rosamund, Husbands, Samantha, Knowles, Helen, Walton, Chloe, Karagama, Yakubu, Heathcote, Kate, Birchall, Martin
Publicado 2017

Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone

por Cottone, Lucia, Ligammari, Lorena, Lee, Hang-Mao, Knowles, Helen J., Henderson, Stephen, Bianco, Sara, Davies, Christopher, Strauss, Sandra, Amary, Fernanda, Leite, Ana Paula, Tirabosco, Roberto, Haendler, Kristian, Schultze, Joachim L., Herrero, Javier, O’Donnell, Paul, Grigoriadis, Agamemnon E., Salomoni, Paolo, Flanagan, Adrienne M.
Publicado 2022