A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges

por di Martino, Erica, Tomlinson, Darren C., Knowles, Margaret A.
Publicado 2012

Oncogenic FGFR3 gene fusions in bladder cancer

por Williams, Sarah V., Hurst, Carolyn D., Knowles, Margaret A.
Publicado 2013

ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer

por di Martino, Erica, Alder, Olivia, Hurst, Carolyn D., Knowles, Margaret A.
Publicado 2019

Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer

por Knowles, Margaret A., Platt, Fiona M., Ross, Rebecca L., Hurst, Carolyn D.
Publicado 2009

Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms

por Pymar, Louis S., Platt, Fiona M., Askham, Jon M., Morrison, Ewan E., Knowles, Margaret A.
Publicado 2008

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene

por Hurst, Carolyn D, Zuiverloon, Tahlita CM, Hafner, Christian, Zwarthoff, Ellen C, Knowles, Margaret A
Publicado 2009

FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms

por Tomlinson, Darren C., Baxter, Euan W., Loadman, Paul M., Hull, Mark A., Knowles, Margaret A.
Publicado 2012

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

por Taylor, Claire F., Platt, Fiona M., Hurst, Carolyn D., Thygesen, Helene H., Knowles, Margaret A.
Publicado 2014

The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets

por Burns, Julie E., Hurst, Carolyn D., Knowles, Margaret A., Phillips, Roger M., Allison, Simon J.
Publicado 2021

Identification of Mutations in Distinct Regions of p85 Alpha in Urothelial Cancer

por Ross, Rebecca L., Burns, Julie E., Taylor, Claire F., Mellor, Paul, Anderson, Deborah H., Knowles, Margaret A.
Publicado 2013

Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms

por Burghel, George J., Hurst, Carolyn D., Watson, Christopher M., Chambers, Phillip A., Dickinson, Helen, Roberts, Paul, Knowles, Margaret A.
Publicado 2015

Modeling the mechanical stiffness of pancreatic ductal adenocarcinoma

por Kpeglo, Delanyo, Hughes, Matthew D.G., Dougan, Lorna, Haddrick, Malcolm, Knowles, Margaret A., Evans, Stephen D., Peyman, Sally A.
Publicado 2022

Two Multiplex Assays That Simultaneously Identify 22 Possible Mutation Sites in the KRAS, BRAF, NRAS and PIK3CA Genes

por Lurkin, Irene, Stoehr, Robert, Hurst, Carolyn D., van Tilborg, Angela A. G., Knowles, Margaret A., Hartmann, Arndt, Zwarthoff, Ellen C.
Publicado 2010

Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms()

por De Faveri, Lia E., Hurst, Carolyn D., Roulson, Jo-An, Wood, Henry, Sanchez-Carbayo, Marta, Knowles, Margaret A., Chapman, Emma J.
Publicado 2015

Functional assays to determine the significance of two common XPC 3'UTR variants found in bladder cancer patients

por Qiao, Boling, Scott, Gina B, Elliott, Faye, Vaslin, Laurence, Bentley, Johanne, Hall, Janet, Bishop, D Timothy, Knowles, Margaret A, Kiltie, Anne E
Publicado 2011

Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation

por Mellor, Paul, Marshall, Jeremy D. S., Ruan, Xuan, Whitecross, Dielle E., Ross, Rebecca L., Knowles, Margaret A., Moore, Stanley A., Anderson, Deborah H.
Publicado 2018

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup

por Baldia, Philipp H., Maurer, Angela, Heide, Timon, Rose, Michael, Stoehr, Robert, Hartmann, Arndt, Williams, Sarah V., Knowles, Margaret A., Knuechel, Ruth, Gaisa, Nadine T.
Publicado 2016

Use of Aleuria alantia Lectin Affinity Chromatography to Enrich Candidate Biomarkers from the Urine of Patients with Bladder Cancer

por Ambrose, Sarah R., Gordon, Naheema S., Goldsmith, James C., Wei, Wenbin, Zeegers, Maurice P., James, Nicholas D., Knowles, Margaret A., Bryan, Richard T., Ward, Douglas G.
Publicado 2015

Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis

por Lombardi, Benedetta, Ashford, Paul, Moya-Garcia, Aurelio A., Rust, Aleksander, Crawford, Mark, Williams, Sarah V., Knowles, Margaret A., Katan, Matilda, Orengo, Christine, Godovac-Zimmermann, Jasminka
Publicado 2017

Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling

por Hurst, Carolyn D, Cheng, Guo, Platt, Fiona M, Alder, Olivia, Black, Emma VI, Burns, Julie E, Brown, Joanne, Jain, Sunjay, Roulson, Jo‐An, Knowles, Margaret A
Publicado 2022